Protein name:
DIS3-like exonuclease 1 ;
Alternative:
Organism:
Rat (Rattus norvegicus).
General Annotation
Sub Unit:
Component of the RNA exosome complex. The catalytically inactive RNA exosome core (Exo-9) complex is believed to associate with catalytic subunits EXOSC10, and DIS3 or DIS3L in cytoplasmic-and nuclear-specific RNA exosome complex forms.
Function:
Putative cytoplasm-specific catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events. In the cytoplasm, the RNA exosome complex is involved in general mRNA turnover and specifically degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3' untranslated regions, and in RNA surveillance pathways, preventing translation of aberrant mRNAs. It seems to be involved in degradation of histone mRNA.
Subcellular Location:
Cytoplasm
Protein Attributes:
50:
MLQKREKVLL | LRTFQGRTLR | IVREHYLRPS | VPCNSPLCPQ | PATCRNDGKL |
100:
LSAEVTHYVI | PDWKVVQDYL | EVLEFPELKG | IIFMQTACQA | VQHQRGRRQY |
150:
NKLRNLLKDA | RHDCVLFANE | FQQHCYLPRE | KGEAMEKWQT | RSIYNSAVWY |
200:
YHHCEDRMPI | VMVTEDEEAI | QQYGSETEGV | FVISFKNYLD | NFWPDLKAAH |
250:
ELCDSIIQSR | RERESESQET | HGKEYPEHLP | LEVLEAGIKS | GRYIQGILNV |
300:
NKHRAQIEAF | VRLQGASSKD | SGLVSDILIH | GSKARNRSIH | GDVVVVELLP |
350:
KSEWKGRTAA | LCENDSEDKA | SGESPSEPMP | TGRVVGILQK | NWRDYVVTFP |
400:
SKEEVQSQGK | NAQKILVTPW | DYRIPKIRIS | TQQAEALQDF | RVVVRIDSWE |
450:
TTSVYPNGHF | VRVLGRIGDL | EGEIATILVE | NSINVVPFSE | AQMCEMPVNT |
500:
AENPWKVSPK | EEQERRDLRS | THLVFSIDPK | GCEDVDDALS | VRTLNNGNLE |
550:
LGVHIADVTH | FVAPNSYIDV | EARTRATTYY | LADRRYDMLP | SILSADLCSL |
600:
LGGVDRYAVS | VMWELDKTSY | EIKKVWYGRT | IIRSAYKLFY | EAAQELLDGN |
650:
FSIVDDIPEF | KTLEEQNRQA | KLEELVWAIG | KLTDIARHIR | AKRDRCGALE |
700:
LEGVEVRVQL | DDKKNIHDLI | PKQPLEVHET | VAECMILANH | WVAKKIWESF |
750:
PHQALLRQHP | PPHQEFFSEL | RECAKAKGFF | IDTRSNKTLA | DSLDSANDPS |
800:
DPLVNKLLRS | MATQAMSNAL | YFSTGSCAEE | EFHHYGLALD | KYTHFTSPIR |
850:
RYSDIVVHRL | LMAAISKDKK | VEIKENLFSN | KNLEELCRHI | NNRNRAAQRS |
900:
QKQSTELFQC | MYFKDRDPET | EERCVVDGII | YSIRTNGVLV | FIPRFGIKGA |
950:
AYLKNKDGLV | ISCGPEGSSE | WKPGSLQRSQ | NKIISTTAGG | QSVTFHLFDH |
1000:
VTVRISVQPS | RCHSDMIRLE | IVSNKPYMMP | NTELCHQSSL | LLKSELVKEV |
1050:
TRSVEEAQLA | QEVKGKVIEE | EHQEYRQTKG | RSLYTLLEEI | RDLALLDVSD |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Bovine
Mouse
Rat
Human
ELISA Kit for Rat DIS3-like exonuclease 1
ELISA Kit for Rat DIS3-like exonuclease 1
ELISA Kit for Rat DIS3-like exonuclease 1
ELISA Kit for Rat DIS3-like exonuclease 1
CLIA Kit for Rat DIS3-like exonuclease 1
CLIA Kit for Rat DIS3-like exonuclease 1
CLIA Kit for Rat DIS3-like exonuclease 1
CLIA Kit for Rat DIS3-like exonuclease 1
Polyclonal Antibody for Rat DIS3-like exonuclease 1
Polyclonal Antibody for Rat DIS3-like exonuclease 1
Polyclonal Antibody for Rat DIS3-like exonuclease 1
Polyclonal Antibody for Rat DIS3-like exonuclease 1
Monoclonal Antibody for Rat DIS3-like exonuclease 1
Monoclonal Antibody for Rat DIS3-like exonuclease 1
Monoclonal Antibody for Rat DIS3-like exonuclease 1
Monoclonal Antibody for Rat DIS3-like exonuclease 1
Protein for Rat DIS3-like exonuclease 1
Protein for Rat DIS3-like exonuclease 1
Protein for Rat DIS3-like exonuclease 1
Protein for Rat DIS3-like exonuclease 1
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
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Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue :
Testis .