DIS3L2 ELISA Kit for Human(Homo sapiens) | EIAab.comDIS3L2 ELISA Kit for Human(Homo sapiens)

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Index > Protein center > DIS3L2(Gene name) > Human

DIS3L2 (Gene name),

DIS3-like exonuclease 2 (Protein name ), DI3L2_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

DIS3L2(FAM6A);

Protein name:

DIS3-like exonuclease 2(hDIS3L2);

Alternative:

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

N/A

Function:

Probable exonuclease.

Subcellular Location:

N/A

Protein Attributes:

Sequence length:

885

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

500:

550:

600:

650:

700:

750:

800:

850:

885:

LKYSAILKRP | GTQGHLGPEK | EEEESDGEPE | DSSTS

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

SMR:

Q8IYB7

MIM:

267000

UniGene:

Hs.471637

STRING:

9606.ENSP00000315569

Pfam:

PF00773

String:

Q8IYB7

KEGG:

hsa:129563

UniGene:

Hs.732236

Uniprot:

Q8IYB7

FOR

ELISA Kit for Human hDIS3L2

CLIA Kit for Human hDIS3L2

Polyclonal Antibody for Human hDIS3L2

Monoclonal Antibody for Human hDIS3L2

Protein for Human hDIS3L2

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 3)
tissue: Cerebellum.
2.

"The full-ORF clone resource of the German cDNA consortium."
Bechtel S. , Rosenfelder H. , Duda A. , Schmidt C.P. , Ernst U. , Wellenreuther R. , Mehrle A. , Schuster C. , Bahr A. , Bloecker H. , Heubner D. , Hoerlein A. , Michel G. , Wedler H. , Koehrer K. , Ottenwaelder B. , Poustka A. , Wiemann S. , more...
BMC Genomics8:399-399(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 4);NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 71-885 (ISOFORM 5)
tissue: Testis.
tissue: Uterus.
3.

Zan Q. , Guo J.H. , Li D. , Yu L.
Submitted (2001-11) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 4)
4.

"Generation and annotation of the DNA sequences of human chromosomes 2 and 4."
Hillier L.W. , Graves T.A. , Fulton R.S. , Fulton L.A. , Pepin K.H. , Minx P. , Wagner-McPherson C. , Layman D. , Wylie K. , Sekhon M. , Becker M.C. , Fewell G.A. , Delehaunty K.D. , Miner T.L. , Nash W.E. , Kremitzki C. , Oddy L. , Du H. , more...
Nature434:724-731(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
5.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2);VARIANT SER-12
tissue: Testis.
6.

"Complex arrangement of genes within a 220-kb region of double-duplicated DNA on human 2q37.1."
Rump A. , Kasper G. , Hayes C. , Wen G. , Starke H. , Liehr T. , Lehmann R. , Lagemann D. , Rosenthal A.
Genomics73:50-55(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION
7.

"Overexpression of the C-type natriuretic peptide (CNP) is associated with overgrowth and bone anomalies in an individual with balanced t(2;7) translocation."
Bocciardi R. , Giorda R. , Buttgereit J. , Gimelli S. , Divizia M.T. , Beri S. , Garofalo S. , Tavella S. , Lerone M. , Zuffardi O. , Bader M. , Ravazzolo R. , Gimelli G.
Hum. Mutat.28:724-731(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: CHROMOSOMAL TRANSLOCATION
8.

"Lysine acetylation targets protein complexes and co-regulates major cellular functions."
Choudhary C. , Kumar C. , Gnad F. , Nielsen M.L. , Rehman M. , Walther T.C. , Olsen J.V. , Mann M.
Science325:834-840(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-252;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
9.

"Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
Olsen J.V. , Vermeulen M. , Santamaria A. , Kumar C. , Miller M.L. , Jensen L.J. , Gnad F. , Cox J. , Jensen T.S. , Nigg E.A. , Brunak S. , Mann M.
Sci. Signal.3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-31;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue: Cervix carcinoma.
10.

"Initial characterization of the human central proteome."
Burkard T.R. , Planyavsky M. , Kaupe I. , Breitwieser F.P. , Buerckstuemmer T. , Bennett K.L. , Superti-Furga G. , Colinge J.
BMC Syst. Biol.5:17-17(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
11.

"Germline mutations in DIS3L2 cause the Perlman syndrome of overgrowth and Wilms tumor susceptibility."
Astuti D. , Morris M.R. , Cooper W.N. , Staals R.H. , Wake N.C. , Fews G.A. , Gill H. , Gentle D. , Shuib S. , Ricketts C.J. , Cole T. , van Essen A.J. , van Lingen R.A. , Neri G. , Opitz J.M. , Rump P. , Stolte-Dijkstra I. , Muller F. , more...
Nat. Genet.44:277-284(2012) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION;VARIANT PRLMNS TYR-489;VARIANTS GLY-483 AND HIS-576;CHARACTERIZATION OF VARIANTS GLY-483 AND HIS-576
12.

"Perlman Syndrome: Overgrowth, Wilms Tumor Predisposition and DIS3L2."
Morris M.R. , Astuti D. , Maher E.R.
Am. J. Med. Genet. C. Semin. Med. Genet.0:0-0(2013) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INVOLVEMENT IN PRLMNS
13.

"Exonuclease hDIS3L2 specifies an exosome-independent 3'-5' degradation pathway of human cytoplasmic mRNA."
Lubas M. , Damgaard C.K. , Tomecki R. , Cysewski D. , Jensen T.H. , Dziembowski A.
EMBO J.32:1855-1868(2013) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;COFACTOR;SUBCELLULAR LOCATION;MUTAGENESIS OF ASP-391;INTERACTION WITH XRN1
14.

"Homozygous deletion of DIS3L2 exon 9 due to non-allelic homologous recombination between LINE-1s in a Japanese patient with Perlman syndrome."
Higashimoto K. , Maeda T. , Okada J. , Ohtsuka Y. , Sasaki K. , Hirose A. , Nomiyama M. , Takayanagi T. , Fukuzawa R. , Yatsuki H. , Koide K. , Nishioka K. , Joh K. , Watanabe Y. , Yoshiura K. , Soejima H.
Eur. J. Hum. Genet.21:1316-1319(2013) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INVOLVEMENT IN PRLMNS
15.

"Mammalian DIS3L2 exoribonuclease targets the uridylated precursors of let-7 miRNAs."
Ustianenko D. , Hrossova D. , Potesil D. , Chalupnikova K. , Hrazdilova K. , Pachernik J. , Cetkovska K. , Uldrijan S. , Zdrahal Z. , Vanacova S.
RNA19:1632-1638(2013) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;SUBCELLULAR LOCATION;COFACTOR;RNA-BINDING;MUTAGENESIS OF ASP-391

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