Akr1c9 ELISA Kit for Rat(Rattus norvegicus) | EIAab.comAkr1c9 ELISA Kit for Rat(Rattus norvegicus)

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Index > Protein center > Akr1c9(Gene name) > Rat

Akr1c9 (Gene name),

3-alpha-hydroxysteroid dehydrogenase (Protein name ), DIDH_RAT from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Akr1c9;

Protein name:

3-alpha-hydroxysteroid dehydrogenase(3-alpha-HSD);

Alternative:

Hydroxyprostaglandin dehydrogenase;

Organism:

Rat (Rattus norvegicus).

General Annotation

Sub Unit:

Monomer.

Function:

Besides being a 3-alpha-hydroxysteroid dehydrogenase, the enzyme can accomplish diverse functions: as quinone reductase, as an aromatic alcohol dehydrogenase, as dihydrodiol dehydrogenase, and as 9-, 11-, and 15-hydroxyprostaglandin dehydrogenase.

Subcellular Location:

Cytoplasm

Protein Attributes:

Sequence length:

322

Sequence:

50:

100:

150:

200:

250:

300:

322:

RNFRYNNAKY | FDDHPNHPFT | DE

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

KEGG:

rno:191574

UniGene:

Rn.10021

Pfam:

PF00248

String:

P23457

SMR:

P23457

Uniprot:

P23457

FOR

ELISA Kit for Rat 3-alpha-HSD

CLIA Kit for Rat 3-alpha-HSD

Polyclonal Antibody for Rat 3-alpha-HSD

Monoclonal Antibody for Rat 3-alpha-HSD

Protein for Rat 3-alpha-HSD

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Cloning and sequencing of the cDNA for rat liver 3 alpha-hydroxysteroid/dihydrodiol dehydrogenase."
Pawlowski J.E. , Huizinga M. , Penning T.M.
J. Biol. Chem.266:8820-8825(1991) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];PARTIAL PROTEIN SEQUENCE
tissue: Liver.
2.

"Molecular structure of rat hepatic 3 alpha-hydroxysteroid dehydrogenase. A member of the oxidoreductase gene family."
Stolz A. , Rahimi-Kiani M. , Ameis D. , Chan E. , Ronk M. , Shively J.E.
J. Biol. Chem.266:15253-15257(1991) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];PARTIAL PROTEIN SEQUENCE
tissue: Liver.
3.

"Molecular cloning and expression of rat liver 3 alpha-hydroxysteroid dehydrogenase."
Cheng K.-C. , White P.C. , Qin K.-N.
Mol. Endocrinol.5:823-828(1991) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
tissue: Liver.
4.

"Rat hepatic 3 alpha-hydroxysteroid dehydrogenase: expression of cDNA and physiological function in bile acid biosynthetic pathway."
Usui E. , Okuda K. , Kato Y. , Noshiro M.
J. Biochem.115:230-237(1994) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
5.

"Genomic structure of rat 3alpha-hydroxysteroid/dihydrodiol dehydrogenase (3alpha-HSD/DD, AKR1C9)."
Lin H.K. , Hung C.F. , Moore M. , Penning T.M.
J. Steroid Biochem. Mol. Biol.71:29-39(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
strain: Sprague-Dawley.
6.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue: Liver.
7.

"Purification of NADPH-dependent dehydroascorbate reductase from rat liver and its identification with 3 alpha-hydroxysteroid dehydrogenase."
Del Bello B. , Maellaro E. , Sugherini L. , Santucci A. , Comporti M. , Casini A.F.
Biochem. J.304:385-390(1994) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 2-16; 121-135; 152-166 AND 203-217
tissue: Liver.
8.

"Isolation and partial characterization of a full-length cDNA clone for 3 alpha-hydroxysteroid dehydrogenase: a potential target enzyme for nonsteroidal anti-inflammatory drugs."
Pawlowski J. , Huizinga M. , Penning T.M.
Agents Actions34:289-293(1991) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 112-169 AND 238-322
9.

"Affinity labeling of 3 alpha-hydroxysteroid dehydrogenase with 3 alpha-bromoacetoxyandrosterone and 11 alpha-bromoacetoxyprogesterone. Isolation and sequence of active site peptides containing reactive cysteines; sequence confirmation using nucleotide sequence from a cDNA clone."
Penning T.M. , Abrams W.R. , Pawlowski J.E.
J. Biol. Chem.266:8826-8834(1991) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 162-171; 208-223 AND 232-246
10.

"Distribution of 3 alpha-hydroxysteroid dehydrogenase in rat brain and molecular cloning of multiple cDNAs encoding structurally related proteins in humans."
Khanna M. , Qin K.-N. , Cheng K.-C.
J. Steroid Biochem. Mol. Biol.53:41-46(1995) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY
tissue: Brain.
11.

"Three-dimensional structure of rat liver 3 alpha-hydroxysteroid/dihydrodiol dehydrogenase: a member of the aldo-keto reductase superfamily."
Hoog S.S. , Pawlowski J.E. , Alzari P.M. , Penning T.M. , Lewis M.
Proc. Natl. Acad. Sci. U.S.A.91:2517-2521(1994) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (3.0 ANGSTROMS)
tissue: Liver.
12.

"Structure of 3 alpha-hydroxysteroid/dihydrodiol dehydrogenase complexed with NADP+."
Bennett M.J. , Schlegel B.P. , Jez J.M. , Penning T.M. , Lewis M.
Biochemistry35:10702-10711(1996) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.7 ANGSTROMS)
13.

"Steroid recognition and regulation of hormone action: crystal structure of testosterone and NADP+ bound to 3 alpha-hydroxysteroid/dihydrodiol dehydrogenase."
Bennett M.J. , Albert R.H. , Jez J.M. , Ma H. , Penning T.M. , Lewis M.
Structure5:799-812(1997) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.50 ANGSTROMS) IN COMPLEX WITH NADP AND TESTOSTERONE

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