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Index > Protein center > Dnajc10(Gene name) > Mouse
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  • Dnajc10 (Gene name),
  • DnaJ homolog subfamily C member 10 (Protein name ),  DJC10_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Dnajc10(Erdj5;Jpdi);
    Protein name:
    DnaJ homolog subfamily C member 10;
    Alternative:
    Endoplasmic reticulum DnaJ-PDI fusion protein 1;ER-resident protein ERdj5(ER-resident protein ERdj5);J domain-containing protein disulfide isomerase-like protein(J domain-containing PDI-like protein;JPDI);
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Interacts with HSPA5 via its J domain.
    Function:
    This endoplasmic reticulum co-chaperone may play a role in protein folding and translocation across the endoplasmic reticulum membrane. May be involved in disulfide formation. May act as a co-chaperone for Hspa5.
    Subcellular Location:
    Secreted Endoplasmic reticulum lumen
    Protein Attributes:
    Sequence length:
    793
    Sequence:
    50:
    MGVWLNKDDF | IRDLKRISLC | LLILYVVVVV | GTDQNFYSLL | GVSKTASSRE | 
    100:
    IRQAFKKLAL | KLHPDKNPNN | PNAHGDFLKI | NRAYEVLKDE | DLRKKYDKYG | 
    150:
    EKGLEDNQGG | QYESWSYYRY | DFGIYDDDPE | IITLERREFD | AAVNSGELWF | 
    200:
    VNFYSPGCSH | CHDLAPTWRE | FAKEVDGLLR | IGAVNCGDDR | MLCRMKGVNS | 
    250:
    YPSLFIFRSG | MAAVKYNGDR | SKESLVAFAM | QHVRSTVTEL | STGNFVNAIE | 
    300:
    TAFAAGVGWL | ITFCSKGEDC | LTSQTRLRLS | GMLDGLVNVG | WVDCDAQDSL | 
    350:
    CKSLDTTAST | TAYFPPGATL | NDREKSSVLF | LNSLDAKEIY | MEIIHNLPDF | 
    400:
    ELLSANQLED | RLAHHRWLVF | FHFGKNENAN | DPELKKLKTL | LKNEHIQVGR | 
    450:
    FDCSSAPGIC | SDLYVFQPCL | AVFKGQGTKE | YEIHHGKKIL | YDILAFAKES | 
    500:
    VNSHVTTLGP | QNFPASDKEP | WLVDFFAPWC | PPCRALLPEL | RKASTLLYGQ | 
    550:
    LKVGTLDCTI | HEGLCNMYNI | QAYPTTVVFN | QSSIHEYEGH | HSAEQILEFI | 
    600:
    EDLRNPSVVS | LTPSTFNELV | KQRKHDEVWM | VDFYSPWCHP | CQVLMPEWKR | 
    650:
    MARTLTGLIN | VGSVDCQQYH | SFCTQENVQR | YPEIRFYPQK | SSKAYQYHSY | 
    700:
    NGWNRDAYSL | RSWGLGFLPQ | ASIDLTPQTF | NEKVLQGKTH | WVVDFYAPWC | 
    750:
    GPCQNFAPEF | ELLARMIKGK | VRAGKVDCQA | YPQTCQKAGI | KAYPSVKLYQ | 
    793:
    YERAKKSIWE | EQINSRDAKT | IAALIYGKLE | TLQSQVKRNK | DEL
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    Pfam:
    KEGG:
    String:
    UniGene:
    SMR:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse DnaJ homolog subfamily C member 10
    ELISA Kit for Mouse DnaJ homolog subfamily C member 10
    ELISA Kit for Mouse DnaJ homolog subfamily C member 10
    CLIA Kit for Mouse DnaJ homolog subfamily C member 10
    CLIA Kit for Mouse DnaJ homolog subfamily C member 10
    CLIA Kit for Mouse DnaJ homolog subfamily C member 10
    Polyclonal Antibody for Mouse DnaJ homolog subfamily C member 10
    Polyclonal Antibody for Mouse DnaJ homolog subfamily C member 10
    Polyclonal Antibody for Mouse DnaJ homolog subfamily C member 10
    Monoclonal Antibody for Mouse DnaJ homolog subfamily C member 10
    Monoclonal Antibody for Mouse DnaJ homolog subfamily C member 10
    Monoclonal Antibody for Mouse DnaJ homolog subfamily C member 10
    Protein for Mouse DnaJ homolog subfamily C member 10
    Protein for Mouse DnaJ homolog subfamily C member 10
    Protein for Mouse DnaJ homolog subfamily C member 10

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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "ERdj5, an endoplasmic reticulum (ER)-resident protein containing DnaJ and thioredoxin domains, is expressed in secretory cells or following ER stress."
      Cunnea P.M. , Miranda-Vizuete A. , Bertoli G. , Simmen T. , Damdimopoulos A.E. , Hermann S. , Leinonen S. , Huikko M.P. , Gustafsson J.-A. , Sitia R. , Spyrou G.
      J. Biol. Chem.278:1059-1066(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];FUNCTION;TISSUE SPECIFICITY
    2. 2.
      "ERDJPs, a novel family of ER chaperones."
      Simmen T. , Mezghrani A. , Bertoli G. , Sitia R.
      Submitted (2000-10) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    3. 3.
      "The transcriptional landscape of the mammalian genome."
      Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
      Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: C57BL/6J.
      tissue: Lung.
    4. 4.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
      strain: C57BL/6J.
    5. 5.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: Czech II.
      strain: FVB/N x C57BL/6J.
      tissue: Mammary tumor.
    6. 6.
      "JPDI, a novel endoplasmic reticulum-resident protein containing both a BiP-interacting J-domain and thioredoxin-like motifs."
      Hosoda A. , Kimata Y. , Tsuru A. , Kohno K.
      J. Biol. Chem.278:2669-2676(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;SUBCELLULAR LOCATION;TISSUE SPECIFICITY;GLYCOSYLATION;INTERACTION WITH HSPA5
    7. 7.
      "ERdj5 is required as a disulfide reductase for degradation of misfolded proteins in the ER."
      Ushioda R. , Hoseki J. , Araki K. , Jansen G. , Thomas D.Y. , Nagata K.
      Science321:569-572(2008) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INTERACTION WITH EDEM1;MUTAGENESIS OF CYS-158; CYS-161; CYS-480; CYS-483; CYS-588; CYS-591; CYS-700 AND CYS-703
    8. 8.
      "Positive contribution of ERdj5/JPDI to endoplasmic reticulum protein quality control in the salivary gland."
      Hosoda A. , Tokuda M. , Akai R. , Kohno K. , Iwawaki T.
      Biochem. J.425:117-125(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: DISRUPTION PHENOTYPE
    9. 9.
      "Structural basis of an ERAD pathway mediated by the ER-resident protein disulfide reductase ERdj5."
      Hagiwara M. , Maegawa K. , Suzuki M. , Ushioda R. , Araki K. , Matsumoto Y. , Hoseki J. , Nagata K. , Inaba K.
      Mol. Cell41:432-444(2011) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.84 ANGSTROMS) OF 33-793;FUNCTION;INTERACTION WITH EDEM1;MUTAGENESIS OF CYS-158; CYS-161; CYS-480; CYS-483; CYS-588; CYS-591; CYS-700 AND CYS-703
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