DND1 ELISA Kit for Human(Homo sapiens) | EIAab.comDND1 ELISA Kit for Human(Homo sapiens)

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Index > Protein center > DND1(Gene name) > Human

DND1 (Gene name),

Dead end protein homolog 1 (Protein name ), DND1_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

DND1(RBMS4);

Protein name:

Dead end protein homolog 1;

Alternative:

RNA-binding motif, single-stranded-interacting protein 4;

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Interacts with APOBEC3.

Function:

RNA-binding factor that positively regulates gene expression by prohibiting miRNA-mediated gene suppression. Relieves miRNA repression in germline cells (By similarity). Prohibits the function of several miRNAs by blocking the accessibility of target mRNAs. Sequence-specific RNA-binding factor that binds specifically to U-rich regions (URRs) in the 3' untranslated region (3'-UTR) of several mRNAs. Does not bind to miRNAs. May play a role during primordial germ cell (PGC) survival (By similarity). However, does not seem to be essential for PGC migration.

Subcellular Location:

Nucleus Cytoplasm Perinuclear germ granules, also called germ plasm or chromatoid body. Colocalizes in perinuclear sites with APOBEC3.

Protein Attributes:

Sequence length:

353

Sequence:

50:

100:

150:

200:

250:

300:

350:

353:

VKQ

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

STRING:

9606.ENSP00000329246

String:

Q8IYX4

MIM:

609385

UniGene:

Hs.591262

KEGG:

hsa:373863

Pfam:

PF00076

SMR:

Q8IYX4

Uniprot:

Q8IYX4

FOR

ELISA Kit for Human Dead end protein homolog 1

CLIA Kit for Human Dead end protein homolog 1

Polyclonal Antibody for Human Dead end protein homolog 1

Monoclonal Antibody for Human Dead end protein homolog 1

Protein for Human Dead end protein homolog 1

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Dead end, a novel vertebrate germ plasm component, is required for zebrafish primordial germ cell migration and survival."
Weidinger G. , Stebler J. , Slanchev K. , Dumstrei K. , Wise C. , Lovell-Badge R. , Thisse C. , Thisse B. , Raz E.
Curr. Biol.13:1429-1434(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
2.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue: Brain.
3.

"RNA-binding protein Dnd1 inhibits microRNA access to target mRNA."
Kedde M. , Strasser M.J. , Boldajipour B. , Oude Vrielink J.A. , Slanchev K. , le Sage C. , Nagel R. , Voorhoeve P.M. , van Duijse J. , Oerom U.A. , Lund A.H. , Perrakis A. , Raz E. , Agami R.
Cell131:1273-1286(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;RNA-BINDING;SUBCELLULAR LOCATION

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