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Index > Protein center > Dner(Gene name) > Mouse
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  • Dner (Gene name),
  • Delta and Notch-like epidermal growth factor-related receptor (Protein name ),  DNER_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Dner(Bet;Bret);
    Protein name:
    Delta and Notch-like epidermal growth factor-related receptor;
    Alternative:
    Brain EGF repeat-containing transmembrane protein;
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Interacts with AP1G1. Interacts with NOTCH1.
    Function:
    Mediates neuron-glia interaction during astrocytogenesis. May promote differentiation of Bergmann glia during cerebellar development by activating DELTEX-dependent NOTCH1 signaling.
    Subcellular Location:
    Cell membrane Single-pass type I membrane protein Present on the membrane of dendrites and cell bodies but excluded from axonal membrane. Also found in early endosomes in the somatodendritic region.
    Protein Attributes:
    Sequence length:
    737
    Sequence:
    50:
    MPPRRAQAPG | APLLPVLALL | PLLLGAGPQS | GCLASPVSAA | PLPAPGPCAS | 
    100:
    QPCRNGGVCT | PRSVTDQEHP | AADAEPRYSC | TCPAGVSGTY | CQFVADPCAS | 
    150:
    NPCHHGNCSS | SSSSSSDSYL | CICNDGYEGL | NCEQPLPSIP | TSGWTESTAP | 
    200:
    RQLQPVPATQ | EPDIILPRSQ | ATVTLPTWQP | KTGQKVVEMK | WDQVEVVPDV | 
    250:
    ACGNASSNNS | AGGRLVSFEV | PQNTSVKIRQ | DANSLLILLW | KVTATGFQQC | 
    300:
    SLIDGRSVTP | LQAPGGLVLL | EEMLALGPNH | FIGFVNDSVA | KSIVALRLTL | 
    350:
    VVKASNCVPG | DSHSNDLECS | GKGKCATKPS | EATFSCTCQD | QYIGTFCEEF | 
    400:
    DACQRKPCQN | EASCIDANEK | QDGSNFTCLC | LPGYTGELCQ | SKIDYCVLDP | 
    450:
    CRNGATCVSS | LSGFTCQCLE | GYFGSACEEK | VDPCMSSPCQ | NNGTCYVDGV | 
    500:
    HFTCSCSPGF | TGPTCAQLVD | FCALSPCAHG | MCRSVGTSYK | CLCDPGYHGL | 
    550:
    YCEEEYNECL | SAPCLNAATC | RDLINGYECV | CLAEYKGTHC | ELYKDPCANI | 
    600:
    SCLNGGTCDS | EGLNGTCICA | PGFTGEECDI | DINECDSNPC | HHAGTCLDQP | 
    650:
    NGYTCHCPHG | WVGANCEIHL | QWKSGHMAES | LTNMPRHSLY | IIIGALCVAF | 
    700:
    ILMLIILIVG | ICRISRIEYQ | GSSRPAYEEF | YNCRSIDSEF | SNAIASIRHA | 
    737:
    RFGKKSRPAM | YDVTPIAYED | YSPDDKPLVT | LIKTKDL
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    Pfam:
    SMR:
    UniGene:
    String:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse Delta and Notch-like epidermal growth factor-related receptor
    ELISA Kit for Mouse Delta and Notch-like epidermal growth factor-related receptor
    CLIA Kit for Mouse Delta and Notch-like epidermal growth factor-related receptor
    CLIA Kit for Mouse Delta and Notch-like epidermal growth factor-related receptor
    Polyclonal Antibody for Mouse Delta and Notch-like epidermal growth factor-related receptor
    Polyclonal Antibody for Mouse Delta and Notch-like epidermal growth factor-related receptor
    Monoclonal Antibody for Mouse Delta and Notch-like epidermal growth factor-related receptor
    Monoclonal Antibody for Mouse Delta and Notch-like epidermal growth factor-related receptor
    Protein for Mouse Delta and Notch-like epidermal growth factor-related receptor
    Protein for Mouse Delta and Notch-like epidermal growth factor-related receptor

    R&D Technical Data
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    Precision
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    Recovery
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Linearity
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    References
    1. 1.
      "Delta/notch-like epidermal growth factor (EGF)-related receptor, a novel EGF-like repeat-containing protein targeted to dendrites of developing and adult central nervous system neurons."
      Eiraku M. , Hirata Y. , Takeshima H. , Hirano T. , Kengaku M.
      J. Biol. Chem.277:25400-25407(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];TISSUE SPECIFICITY;DEVELOPMENTAL STAGE;SUBCELLULAR LOCATION;MUTAGENESIS OF TYR-677;INTERACTION WITH AP1G1
      strain: ICR.
      tissue: Brain.
    2. 2.
      "BET, a novel neuronal transmembrane protein with multiple EGF-like motifs."
      Nishizumi H. , Komiyama T. , Miyabayashi T. , Sakano S. , Sakano H.
      NeuroReport13:909-915(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];SUBCELLULAR LOCATION;TISSUE SPECIFICITY;DEVELOPMENTAL STAGE;GLYCOSYLATION
      strain: C57BL/6J.
      tissue: Brain.
    3. 3.
      "The transcriptional landscape of the mammalian genome."
      Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
      Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: C57BL/6J.
      tissue: Bone marrow.
      tissue: Retina.
    4. 4.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: FVB/N.
      tissue: Colon.
      tissue: Eye.
    5. 5.
      "DNER acts as a neuron-specific Notch ligand during Bergmann glial development."
      Eiraku M. , Tohgo A. , Ono K. , Kaneko M. , Fujishima K. , Hirano T. , Kengaku M.
      Nat. Neurosci.8:873-880(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH NOTCH1;FUNCTION
    6. 6.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;DISRUPTION PHENOTYPE
    7. 7.
      "Large-scale identification and evolution indexing of tyrosine phosphorylation sites from murine brain."
      Ballif B.A. , Carey G.R. , Sunyaev S.R. , Gygi S.P.
      J. Proteome Res.7:311-318(2008) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT TYR-711 AND TYR-721;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Brain.
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