Protein name:
DNA polymerase beta ;
Alternative:
Organism:
Mouse (Mus musculus).
General Annotation
Sub Unit:
Monomer. Interacts with APEX1, HUWE1/ARF-BP1, STUB1/CHIP and USP47.
Function:
Repair polymerase that plays a key role in base-excision repair. Has 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity that removes the 5' sugar phosphate and also acts as a DNA polymerase that adds one nucleotide to the 3' end of the arising single-nucleotide gap. Conducts 'gap-filling' DNA synthesis in a stepwise distributive fashion rather than in a processive fashion as for other DNA polymerases.
Subcellular Location:
Nucleus
Cytoplasm
Cytoplasmic in normal conditions. Translocates to the nucleus following DNA damage.
Protein Attributes:
50:
MSKRKAPQET | LNGGITDMLV | ELANFEKNVS | QAIHKYNAYR | KAASVIAKYP |
100:
HKIKSGAEAK | KLPGVGTKIA | EKIDEFLATG | KLRKLEKIRQ | DDTSSSINFL |
150:
TRVTGIGPSA | ARKFVDEGIK | TLEDLRKNED | KLNHHQRIGL | KYFEDFEKRI |
200:
PREEMLQMQD | IVLNEIKKVD | SEYIATVCGS | FRRGAESSGD | MDVLLTHPNF |
250:
TSESSKQPKL | LHRVVEQLQK | VHFITDTLSK | GETKFMGVCQ | LPSEKDGKEY |
300:
PHRRIDIRLI | PKDQYYCGVL | YFTGSDIFNK | NMRAHALEKG | FTINEYTIRP |
335:
LGVTGVAGEP | LPVDSEQDIF | DYIQWRYREP | KDRSE
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Mouse
Human
Rat
Bovine
ELISA Kit for Mouse DNA polymerase beta
ELISA Kit for Mouse DNA polymerase beta
ELISA Kit for Mouse DNA polymerase beta
ELISA Kit for Mouse DNA polymerase beta
CLIA Kit for Mouse DNA polymerase beta
CLIA Kit for Mouse DNA polymerase beta
CLIA Kit for Mouse DNA polymerase beta
CLIA Kit for Mouse DNA polymerase beta
Polyclonal Antibody for Mouse DNA polymerase beta
Polyclonal Antibody for Mouse DNA polymerase beta
Polyclonal Antibody for Mouse DNA polymerase beta
Polyclonal Antibody for Mouse DNA polymerase beta
Monoclonal Antibody for Mouse DNA polymerase beta
Monoclonal Antibody for Mouse DNA polymerase beta
Monoclonal Antibody for Mouse DNA polymerase beta
Monoclonal Antibody for Mouse DNA polymerase beta
Protein for Mouse DNA polymerase beta
Protein for Mouse DNA polymerase beta
Protein for Mouse DNA polymerase beta
Protein for Mouse DNA polymerase beta
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
strain :
129/Ola .
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[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
strain :
C57BL/6J .
tissue :
Amnion .
tissue :
Bone marrow .
tissue :
Testis .
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue :
Mammary gland .
tissue :
Testis .
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Mol. Cell50:919-930(2013)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-72;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue :
Embryonic fibroblast .