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Index > Protein center > Polb(Gene name) > Mouse
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  • Polb (Gene name),
  • DNA polymerase beta (Protein name ),  DPOLB_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Polb;
    Protein name:
    DNA polymerase beta;
    Alternative:

    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Monomer. Interacts with APEX1, HUWE1/ARF-BP1, STUB1/CHIP and USP47.
    Function:
    Repair polymerase that plays a key role in base-excision repair. Has 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity that removes the 5' sugar phosphate and also acts as a DNA polymerase that adds one nucleotide to the 3' end of the arising single-nucleotide gap. Conducts 'gap-filling' DNA synthesis in a stepwise distributive fashion rather than in a processive fashion as for other DNA polymerases.
    Subcellular Location:
    Nucleus Cytoplasm Cytoplasmic in normal conditions. Translocates to the nucleus following DNA damage.
    Protein Attributes:
    Sequence length:
    335
    Sequence:
    50:
    MSKRKAPQET | LNGGITDMLV | ELANFEKNVS | QAIHKYNAYR | KAASVIAKYP | 
    100:
    HKIKSGAEAK | KLPGVGTKIA | EKIDEFLATG | KLRKLEKIRQ | DDTSSSINFL | 
    150:
    TRVTGIGPSA | ARKFVDEGIK | TLEDLRKNED | KLNHHQRIGL | KYFEDFEKRI | 
    200:
    PREEMLQMQD | IVLNEIKKVD | SEYIATVCGS | FRRGAESSGD | MDVLLTHPNF | 
    250:
    TSESSKQPKL | LHRVVEQLQK | VHFITDTLSK | GETKFMGVCQ | LPSEKDGKEY | 
    300:
    PHRRIDIRLI | PKDQYYCGVL | YFTGSDIFNK | NMRAHALEKG | FTINEYTIRP | 
    335:
    LGVTGVAGEP | LPVDSEQDIF | DYIQWRYREP | KDRSE
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    SMR:
    String:
    KEGG:
    Pfam:
    Pfam:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse DNA polymerase beta
    ELISA Kit for Mouse DNA polymerase beta
    ELISA Kit for Mouse DNA polymerase beta
    ELISA Kit for Mouse DNA polymerase beta
    CLIA Kit for Mouse DNA polymerase beta
    CLIA Kit for Mouse DNA polymerase beta
    CLIA Kit for Mouse DNA polymerase beta
    CLIA Kit for Mouse DNA polymerase beta
    Polyclonal Antibody for Mouse DNA polymerase beta
    Polyclonal Antibody for Mouse DNA polymerase beta
    Polyclonal Antibody for Mouse DNA polymerase beta
    Polyclonal Antibody for Mouse DNA polymerase beta
    Monoclonal Antibody for Mouse DNA polymerase beta
    Monoclonal Antibody for Mouse DNA polymerase beta
    Monoclonal Antibody for Mouse DNA polymerase beta
    Monoclonal Antibody for Mouse DNA polymerase beta
    Protein for Mouse DNA polymerase beta
    Protein for Mouse DNA polymerase beta
    Protein for Mouse DNA polymerase beta
    Protein for Mouse DNA polymerase beta

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Sequence of mouse DNA polymerase beta."
      Poltoratsky V.P. , Wilson S.H.
      Submitted (2002-05) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      strain: 129/Ola.
    2. 2.
      "The transcriptional landscape of the mammalian genome."
      Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
      Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: C57BL/6J.
      tissue: Amnion.
      tissue: Bone marrow.
      tissue: Testis.
    3. 3.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Mammary gland.
      tissue: Testis.
    4. 4.
      "SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways."
      Park J. , Chen Y. , Tishkoff D.X. , Peng C. , Tan M. , Dai L. , Xie Z. , Zhang Y. , Zwaans B.M. , Skinner M.E. , Lombard D.B. , Zhao Y.
      Mol. Cell50:919-930(2013) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-72;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Embryonic fibroblast.
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