Gene name:
DSCAML1 (DSCAM2;KIAA1132) ;
Protein name:
Down syndrome cell adhesion molecule-like protein 1 ;
Alternative:
Down syndrome cell adhesion molecule 2 ;
Organism:
Human (Homo sapiens).
General Annotation
Function:
Cell adhesion molecule that plays a role in neuronal self-avoidance. Promotes repulsion between specific neuronal processes of either the same cell or the same subtype of cells. Promotes both isoneuronal self-avoidance for creating an orderly neurite arborization in retinal rod bipolar cells and heteroneuronal self-avoidance to maintain mosaic spacing between AII amacrine cells.
Subcellular Location:
Cell membrane
Single-pass type I membrane protein
Protein Attributes:
50:
MWLVTFLLLL | DSLHKARPED | VGTSLYFVND | SLQQVTFSSS | VGVVVPCPAA |
100:
GSPSAALRWY | LATGDDIYDV | PHIRHVHANG | TLQLYPFSPS | AFNSFIHDND |
150:
YFCTAENAAG | KIRSPNIRVK | AVFREPYTVR | VEDQRSMRGN | VAVFKCLIPS |
200:
SVQEYVSVVS | WEKDTVSIIP | EHRFFITYHG | GLYISDVQKE | DALSTYRCIT |
250:
KHKYSGETRQ | SNGARLSVTD | PAESIPTILD | GFHSQEVWAG | HTVELPCTAS |
300:
GYPIPAIRWL | KDGRPLPADS | RWTKRITGLT | ISDLRTEDSG | TYICEVTNTF |
350:
GSAEATGILM | VIDPLHVTLT | PKKLKTGIGS | TVILSCALTG | SPEFTIRWYR |
400:
NTELVLPDEA | ISIRGLSNET | LLITSAQKSH | SGAYQCFATR | KAQTAQDFAI |
450:
IALEDGTPRI | VSSFSEKVVN | PGEQFSLMCA | AKGAPPPTVT | WALDDEPIVR |
500:
DGSHRTNQYT | MSDGTTISHM | NVTGPQIRDG | GVYRCTARNL | VGSAEYQARI |
550:
NVRGPPSIRA | MRNITAVAGR | DTLINCRVIG | YPYYSIKWYK | DALLLPDNHR |
600:
QVVFENGTLK | LTDVQKGMDE | GEYLCSVLIQ | PQLSISQSVH | VAVKVPPLIQ |
650:
PFEFPPASIG | QLLYIPCVVS | SGDMPIRITW | RKDGQVIISG | SGVTIESKEF |
700:
MSSLQISSVS | LKHNGNYTCI | ASNAAATVSR | ERQLIVRVPP | RFVVQPNNQD |
750:
GIYGKAGVLN | CSVDGYPPPK | VMWKHAKGSG | NPQQYHPVPL | TGRIQILPNS |
800:
SLLIRHVLEE | DIGYYLCQAS | NGVGTDISKS | MFLTVKIPAM | ITSHPNTTIA |
850:
IKGHAKELNC | TARGERPIII | RWEKGDTVID | PDRVMRYAIA | TKDNGDEVVS |
900:
TLKLKPADRG | DSVFFSCHAI | NSYGEDRGLI | QLTVQEPPDP | PELEIREVKA |
950:
RSMNLRWTQR | FDGNSIITGF | DIEYKNKSDS | WDFKQSTRNI | SPTINQANIV |
1000:
DLHPASVYSI | RMYSFNKIGR | SEPSKELTIS | TEEAAPDGPP | MDVTLQPVTS |
1050:
QSIQVTWKAP | KKELQNGVIR | GYQIGYRENS | PGSNGQYSIV | EMKATGDSEV |
1100:
YTLDNLKKFA | QYGVVVQAFN | RAGTGPSSSE | INATTLEDVP | SQPPENVRAL |
1150:
SITSDVAVIS | WSEPPRSTLN | GVLKGYRVIF | WSLYVDGEWG | EMQNITTTRE |
1200:
RVELRGMEKF | TNYSVQVLAY | TQAGDGVRSS | VLYIQTKEDV | PGPPAGIKAV |
1250:
PSSASSVVVS | WLPPTKPNGV | IRKYTIFCSS | PGSGQPAPSE | YETSPEQLFY |
1300:
RIAHLNRGQQ | YLLWVAAVTS | AGRGNSSEKV | TIEPAGKAPA | KIISFGGTVT |
1350:
TPWMKDVRLP | CNSVGDPAPA | VKWTKDSEDS | AIPVSMDGHR | LIHTNGTLLL |
1400:
RAVKAEDSGY | YTCTATNTGG | FDTIIVNLLV | QVPPDQPRLT | VSKTSASSIT |
1450:
LTWIPGDNGG | SSIRGFVLQY | SVDNSEEWKD | VFISSSERSF | KLDSLKCGTW |
1500:
YKVKLAAKNS | VGSGRISEII | EAKTHGREPS | FSKDQHLFTH | INSTHARLNL |
1550:
QGWNNGGCPI | TAIVLEYRPK | GTWAWQGLRA | NSSGEVFLTE | LREATWYELR |
1600:
MRACNSAGCG | NETAQFATLD | YDGSTIPPIK | SAQGEGDDVK | KLFTIGCPVI |
1650:
LATLGVALLF | IVRKKRKEKR | LKRLRDAKSL | AEMLISKNNR | SFDTPVKGPP |
1700:
QGPRLHIDIP | RVQLLIEDKE | GIKQLGDDKA | TIPVTDAEFS | QAVNPQSFCT |
1750:
GVSLHHPTLI | QSTGPLIDMS | DIRPGTNPVS | RKNVKSAHST | RNRYSSQWTL |
1800:
TKCQASTPAR | TLTSDWRTVG | SQHGVTVTES | DSYSASLSQD | TDKGRNSMVS |
1850:
TESASSTYEE | LARAYEHAKL | EEQLQHAKFE | ITECFISDSS | SDQMTTGTNE |
1900:
NADSMTSMST | PSEPGICRFT | ASPPKPQDAD | RGKNVAVPIP | HRANKSDYCN |
1950:
LPLYAKSEAF | FRKADGREPC | PVVPPREASI | RNLARTYHTQ | ARHLTLDPAS |
2000:
KSLGLPHPGA | PAAASTATLP | QRTLAMPAPP | AGTAPPAPGP | TPAEPPTAPS |
2050:
AAPPAPSTEP | PRAGGPHTKM | GGSRDSLLEM | STSGVGRSQK | QGAGAYSKSY |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Mouse
Human
ELISA Kit for Human Down syndrome cell adhesion molecule-like protein 1
ELISA Kit for Human Down syndrome cell adhesion molecule-like protein 1
CLIA Kit for Human Down syndrome cell adhesion molecule-like protein 1
CLIA Kit for Human Down syndrome cell adhesion molecule-like protein 1
Polyclonal Antibody for Human Down syndrome cell adhesion molecule-like protein 1
Polyclonal Antibody for Human Down syndrome cell adhesion molecule-like protein 1
Monoclonal Antibody for Human Down syndrome cell adhesion molecule-like protein 1
Monoclonal Antibody for Human Down syndrome cell adhesion molecule-like protein 1
Protein for Human Down syndrome cell adhesion molecule-like protein 1
Protein for Human Down syndrome cell adhesion molecule-like protein 1
R&D Technical Data
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Precision
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Recovery
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Linearity
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