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Index > Protein center > Duox1(Gene name) > Rat
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  • Duox1 (Gene name),
  • Dual oxidase 1 (Protein name ),  DUOX1_RAT from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    Duox1;
    Protein name:
    Dual oxidase 1;
    Alternative:

    Organism:
    Rat (Rattus norvegicus). 
    General Annotation
    Sub Unit:
    Interacts with TXNDC11, TPO and CYBA.
    Function:
    Generates hydrogen peroxide which is required for the activity of thyroid peroxidase/TPO and lactoperoxidase/LPO. Plays a role in thyroid hormones synthesis and lactoperoxidase-mediated antimicrobial defense at the surface of mucosa. May have its own peroxidase activity through its N-terminal peroxidase-like domain.
    Subcellular Location:
    Apical cell membrane Multi-pass membrane protein Localizes to the apical membrane of epithelial cells.
    Protein Attributes:
    Sequence length:
    1551
    Sequence:
    50:
    MAVYSAVAWI | LLFGVLASLG | AQNPVSWEVQ | RFDGWYNNLM | EHRWGSKGSR | 
    100:
    LQRLVPASYA | DGVYQPLREP | YLPNPRHLSN | RVMRGPAGQP | SLRNRTVLGV | 
    150:
    FFGYHVLSDL | VSVETPGCPA | EFLNIYIPRG | DPVFDPDKRG | NVVLPFQRSR | 
    200:
    WDRSTGQSPS | NPRDLTNQVT | GWLDGSAIYG | SSHSWSDTLR | SFSGGQLASG | 
    250:
    PDPAFPRNSQ | NSLLMWMAPD | PATGQGGPQG | LYAFGAQRGN | REPFLQALGL | 
    300:
    LWFRYHNLCA | KRLAQEHPHW | GDEELFQHAR | KRVIATYQNI | AMYEWLPSFL | 
    350:
    KQTPPEYPGY | HPFLDPSISP | EFVVASEQFL | STMVPPGVYM | RNASCHFQGI | 
    400:
    ANRNSSVSGA | LRVCNSYWSR | ENPKLQRAED | VDALLLGMAS | QIAEREDHLV | 
    450:
    VEDVQDFWPG | PLKFSRTDYL | ASCLQRGRDL | GLPSYTKARE | ALGLPPVSHW | 
    500:
    QDINPALSRS | NGTVLEATAA | LYNQDLSRLE | LLAGGLLESH | GDPGPLFSAI | 
    550:
    VLDQFVRLRD | GDRYWFENNR | NGLFSKEEIA | EIRNTSLRDI | LVAVTNVDPS | 
    600:
    ALQPSVFFWL | AGDPCPQPSQ | LSTQGLPACA | PLFVRDYFKG | SGFGFGLTIG | 
    650:
    TLCCFPLVSL | LSAWIVARLR | MRNFKRLQRQ | DRQSIMCEKL | VGGVEALEWQ | 
    700:
    GRKEPCRPVL | VHLQPGQIRV | VDGRLTVLRT | IQLRPPQQVN | LILSSNRGRR | 
    750:
    TLLLKIPKEY | DLVLLFNMEE | ERQALVENIR | AALKENGLSF | QEWELREQEL | 
    800:
    MRAAVTRQQR | GHLLETFFRH | LFSQVLDINQ | ADAGTLPLDS | STKVREALTC | 
    850:
    ELSRAEFADS | LGLKPQDMFV | ESMFSLADKD | GNGYLSFREF | LDILVVFMKG | 
    900:
    SPEEKSRLMF | RMYDFDGNGL | ISKDEFIRML | RSFIEISNNC | LSKDQLAEVV | 
    950:
    ESMFRESGFQ | DKEELTWEDF | HFMLRDHDSD | LRFTQLCVKG | VEVPEVIKNL | 
    1000:
    CRRASYISQE | KICPSPRMSA | HCARNNTKTA | SSPQRLQCPV | DTDPPQEIRR | 
    1050:
    RFGKKVTSFQ | PLLFTEAHRE | KFQRSRRHQT | VQQFKRFIEN | YRRHIGCVAV | 
    1100:
    FYTITGALFL | ERAYYYAFAA | HHSGITDTTR | VGIILSRGTA | ASISFMFSYI | 
    1150:
    LLTMCRNLIT | FLRETFLNRY | IPFDAAVDFH | RFIASTAIIL | TVLHSAGHVV | 
    1200:
    NVYLFSISPL | SVLSCLFPDL | FHDDGSEFPQ | KYYWWFFQTV | PGLTGVLLLL | 
    1250:
    ALAIMYVFAS | HHFRRRSFRG | FWLTHHLYIF | LYILLIIHGS | FALIQMPRFH | 
    1300:
    IFFLVPAIIY | VGDKLVSLSR | KKVEISVVKA | ELLPSGVTHL | RFQRPQGFEY | 
    1350:
    KSGQWVRIAC | LALGTTEYHP | FTLTSAPHED | TLSLHIRAAG | PWTTRLREIY | 
    1400:
    SPPTGDTCAR | YPKLYLDGPF | GEGHQEWHKF | EVSVLVGAGI | GVTPFASILK | 
    1450:
    DLVFKSSVSC | QVFCKKIYFI | WVTRTQRQFE | WLADIIREVE | ENDSRDLVSV | 
    1500:
    HIYITQLAEK | FDLRTTMLYI | CERHFQKVLN | RSLFTGLRSV | THFGRPPFEP | 
    1550:
    FFNSLQEVHP | QVRKIGVFSC | GPPGMTKNVE | KACQLINKQD | RTHFSHHYEN | 
    1551:
    F
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
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    Related Databases
    UniGene:
    String:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Rat Dual oxidase 1
    Cat.:
    E15381h
    Price:
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    MSDS:
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    Packing:
    96T
    Range:
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    ELISA Kit for Rat Dual oxidase 1
    Cat.:
    E15381r
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    ELISA Kit for Rat Dual oxidase 1
    Cat.:
    E15381d
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    MSDS:
    Please sign in first.
    Packing:
    96T
    ELISA Kit for Rat Dual oxidase 1
    Cat.:
    E15381p
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat Dual oxidase 1
    Cat.:
    U15381h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat Dual oxidase 1
    Cat.:
    U15381p
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat Dual oxidase 1
    Cat.:
    U15381d
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat Dual oxidase 1
    Cat.:
    U15381r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Rat Dual oxidase 1
    Polyclonal Antibody for Rat Dual oxidase 1
    Polyclonal Antibody for Rat Dual oxidase 1
    Cat.:
    P15381Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Rat Dual oxidase 1
    Cat.:
    P15381Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Rat Dual oxidase 1
    Monoclonal Antibody for Rat Dual oxidase 1
    Monoclonal Antibody for Rat Dual oxidase 1
    Monoclonal Antibody for Rat Dual oxidase 1
    Protein for Rat Dual oxidase 1
    Protein for Rat Dual oxidase 1
    Protein for Rat Dual oxidase 1
    Protein for Rat Dual oxidase 1

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    References
    1. 1.
      "Identification of a truncated dual oxidase 2 (DUOX2) messenger ribonucleic acid (mRNA) in two rat thyroid cell lines. Insulin and forskolin regulation of DUOX2 mRNA levels in FRTL-5 cells and porcine thyrocytes."
      Morand S. , Dos Santos O.F. , Ohayon R. , Kaniewski J. , Noel-Hudson M.-S. , Virion A. , Dupuy C.
      Endocrinology144:567-574(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      strain: Fischer 344.
    2. 2.
      "Cloning of two human thyroid cDNAs encoding new members of the NADPH oxidase family."
      De Deken X. , Wang D. , Many M.-C. , Costagliola S. , Libert F. , Vassart G. , Dumont J.E. , Miot F.
      J. Biol. Chem.275:23227-23233(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY
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