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Index > Protein center > Dxo(Gene name) > Rat
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  • Dxo (Gene name),
  • Decapping and exoribonuclease protein (Protein name ),  DXO_RAT from NCBI database.
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  • Gene name:
    Dxo(Dom3z);
    Protein name:
    Decapping and exoribonuclease protein(DXO);
    Alternative:
    Dom-3 homolog Z;
    Organism:
    Rat (Rattus norvegicus). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Ribonuclease that specifically degrades pre-mRNAs with a defective 5' end cap and is part of a pre-mRNA capping quality control. Has decapping, pyrophosphohydrolase and 5'-3' exonuclease activities. Has decapping activity toward incomplete 5' end cap mRNAs such as unmethylated 5' end-capped RNA to release GpppN and 5' end monophosphate RNA. The 5' end monophosphate RNA is then degraded by the 5'-3' exoribonuclease activity, enabling this enzyme to decap and degrade incompletely capped mRNAs. Also possesses RNA 5'-pyrophosphohydrolase activity by hydrolyzing the 5' end triphosphate to release pyrophosphates.
    Subcellular Location:
    Nucleus
    Protein Attributes:
    Sequence length:
    397
    Sequence:
    50:
    MEPRGTKRKA | EKTEVAKTWN | KLPRSLPSLR | TQPSLYSGPF | PFYRRPSELG | 
    100:
    CFSLDAQRQY | HGDARALRYY | SPPPINGPGP | DFDLRDGYPD | RYQPRDEEVR | 
    150:
    ERLDHLLRWV | LEHRNQLEGG | PGWLAGATVT | WRGHLTKLLT | TPYERQEGWQ | 
    200:
    LAASRFQGTL | YLSEVETPAA | RAQRLARPPL | LRELMYMGYK | FEQYMCADKP | 
    250:
    GGSPDPSGEV | NTNVAFCSVL | RSRLGNHPLL | FSGEVDCLNP | QAPCTQPPSC | 
    300:
    YVELKTSKEM | HSPGQWRSFY | RHKLLKWWAQ | SFLPGVPYVV | AGFRNPEGFV | 
    350:
    CSLKTFPTME | MFENVRNDQE | GWNPSVCMNF | CAAFLSFAQS | TVVQDDPRLV | 
    397:
    HLFSWEPGGP | VTVSVHRDAP | YAFLPSWYVE | AMTQDLPSLS | KTPSPKD
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    UniGene:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Rat DXO
    ELISA Kit for Rat DXO
    ELISA Kit for Rat DXO
    ELISA Kit for Rat DXO
    CLIA Kit for Rat DXO
    CLIA Kit for Rat DXO
    CLIA Kit for Rat DXO
    CLIA Kit for Rat DXO
    Polyclonal Antibody for Rat DXO
    Polyclonal Antibody for Rat DXO
    Polyclonal Antibody for Rat DXO
    Polyclonal Antibody for Rat DXO
    Monoclonal Antibody for Rat DXO
    Monoclonal Antibody for Rat DXO
    Monoclonal Antibody for Rat DXO
    Monoclonal Antibody for Rat DXO
    Protein for Rat DXO
    Protein for Rat DXO
    Protein for Rat DXO
    Protein for Rat DXO

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    References
    1. 1.
      "The genomic sequence and comparative analysis of the rat major histocompatibility complex."
      Hurt P. , Walter L. , Sudbrak R. , Klages S. , Mueller I. , Shiina T. , Inoko H. , Lehrach H. , Guenther E. , Reinhardt R. , Himmelbauer H.
      Genome Res.14:631-639(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
      strain: Brown Norway.
    2. 2.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Testis.
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