DNAH11 ELISA Kit for Human(Homo sapiens) | EIAab.comDNAH11 ELISA Kit for Human(Homo sapiens)

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Index > Protein center > DNAH11(Gene name) > Human

DNAH11 (Gene name),

Dynein heavy chain 11, axonemal (Protein name ), DYH11_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

DNAH11;

Protein name:

Dynein heavy chain 11, axonemal;

Alternative:

Ciliary dynein heavy chain 11;Axonemal beta dynein heavy chain 11;

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Consists of at least two heavy chains and a number of intermediate and light chains.

Function:

Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP.

Subcellular Location:

Cytoplasm cytoskeleton cilium axoneme

Protein Attributes:

Sequence length:

4523

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FRLKSEEKTA | KWVLAGVALL | LEA

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

STRING:

9606.ENSP00000387188

String:

Q96DT5

UniGene:

Hs.520245

MIM:

244400

Pfam:

PF07728

KEGG:

hsa:8701

Uniprot:

Q96DT5

FOR

ELISA Kit for Human Dynein heavy chain 11, axonemal

CLIA Kit for Human Dynein heavy chain 11, axonemal

Polyclonal Antibody for Human Dynein heavy chain 11, axonemal

Monoclonal Antibody for Human Dynein heavy chain 11, axonemal

Protein for Human Dynein heavy chain 11, axonemal

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Mutations in the DNAH11 (axonemal heavy chain dynein type 11) gene cause one form of situs inversus totalis and most likely primary ciliary dyskinesia."
Bartoloni L. , Blouin J.-L. , Pan Y. , Gehrig C. , Maiti A.K. , Scamuffa N. , Rossier C. , Jorissen M. , Armengot M. , Meeks M. , Mitchison H.M. , Chung E.M.K. , Delozier-Blanchet C.D. , Craigen W.J. , Antonarakis S.E.
Proc. Natl. Acad. Sci. U.S.A.99:10282-10286(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];INVOLVEMENT IN KTGS;VARIANT CILD7 GLN-3004;VARIANTS LEU-34; ARG-639; CYS-654; ALA-1023; ALA-1038; GLY-1640; ASN-2641; THR-3474; VAL-3715; PRO-3765; VAL-4172 AND ILE-4177
tissue: Nasal epithelium.
tissue: Testis.
2.

"The DNA sequence of human chromosome 7."
Hillier L.W. , Fulton R.S. , Fulton L.A. , Graves T.A. , Pepin K.H. , Wagner-McPherson C. , Layman D. , Maas J. , Jaeger S. , Walker R. , Wylie K. , Sekhon M. , Becker M.C. , O'Laughlin M.D. , Schaller M.E. , Fewell G.A. , Delehaunty K.D. , Miner T.L. , more...
Nature424:157-164(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
3.

"Chromosomal localization of human dynein heavy chain genes."
Maiti A.K. , Mattei M.-G. , Jorissen M. , Volz A. , Ziegler A. , Bouvagnet P.
Submitted (1999-01) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 1904-2004
tissue: Nasal polyp.
4.

"Primary ciliary dyskinesia associated with normal axoneme ultrastructure is caused by DNAH11 mutations."
Schwabe G.C. , Hoffmann K. , Loges N.T. , Birker D. , Rossier C. , de Santi M.M. , Olbrich H. , Fliegauf M. , Failly M. , Liebers U. , Collura M. , Gaedicke G. , Mundlos S. , Wahn U. , Blouin J.-L. , Niggemann B. , Omran H. , Antonarakis S.E. , more...
Hum. Mutat.29:289-298(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INVOLVEMENT IN CILD7;INVOLVEMENT IN KTGS;VARIANTS ALA-1023; ALA-1038; ASN-2641; VAL-3715; VAL-4172 AND ILE-4177

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