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Index > Protein center > DNAH12(Gene name) > Human
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  • DNAH12 (Gene name),
  • Dynein heavy chain 12, axonemal (Protein name ),  DYH12_HUMAN from NCBI database.
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  • Antigen Annotation
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  • Gene name:
    DNAH12(DHC3;DLP12;DNAH12L;DNAH7L;DNAHC3;DNHD2;HDHC3;HL19);
    Protein name:
    Dynein heavy chain 12, axonemal;
    Alternative:
    Axonemal dynein heavy chain 12-like protein;Axonemal beta dynein heavy chain 12;Ciliary dynein heavy chain 12;Axonemal dynein heavy chain 7-like protein;Dynein heavy chain domain-containing protein 2;Dynein heavy chain 7-like, axonemal;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Consists of at least two heavy chains and a number of intermediate and light chains.
    Function:
    Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP. Involved in sperm motility; implicated in sperm flagellar assembly.
    Subcellular Location:
    Cytoplasm cytoskeleton cilium axoneme
    Protein Attributes:
    Sequence length:
    3092
    Sequence:
    50:
    MSDANKAAIA | AEKEALNLKL | PPIVHLPENI | GVDTPTQSKL | LKYRRSKEQQ | 
    100:
    QKINQLVIDG | AKRNLDRTLG | KRTPLLPPPD | YPQTMTSEMK | KKGFNYIYMK | 
    150:
    QCVESSPLVP | IQQEWLDHML | RLIPESLKEG | KEREELLESL | INEVSSDFEN | 
    200:
    SMKRYLVQSV | LVKPPVKSLE | DEGGPLPESP | VGLDYSNPWH | SSYVQARNQI | 
    250:
    FSNLHIIHPT | MKMLLDLGYT | TFADTVLLDF | TGIRAKGPID | CESLKTDLSI | 
    300:
    QTRNAEEKIM | NTWYPKVINL | FTKKEALEGV | KPEKLDAFYS | CVSTLMSNQL | 
    350:
    KDLLRRTVEG | FVKLFDPKDQ | QRLPIFKIEL | TFDDDKMEFY | PTFQDLEDNV | 
    400:
    LSLVERIAEA | LQNVQTIPSW | LSGTSTPVNL | DTELPEHVLH | WAVDTLKAAV | 
    450:
    HRNLEGARKH | YETYVEKYNW | LLDGTAVENI | ETFQTEDHTF | DEYTEFIEKF | 
    500:
    LSLASEIMLL | PQWIHYTMVR | LDCEDLKTGL | TNKAKAFANI | LLNDIASKYR | 
    550:
    KENECICSEF | EAIKEHALKV | PETTEEMMDL | ISYVEKARTV | GIEELILRIQ | 
    600:
    ESKRQMSYFL | DVFLFPQEDL | ALNATVLMWP | RKINPIFDEN | DELIENAKHK | 
    650:
    KENELMAKRE | KLILEIEKES | RRMEEFTEFA | ELERMQQYVT | DVRQLQKRIQ | 
    700:
    ESEEAVQFIN | KEEELFKWEL | TKYPELDKLK | VNIEPYQKFF | NFVLKWQRSE | 
    750:
    KRWMDGGFLD | LNGESMEADV | EEFSREIFKT | LKFFQTKLKK | ELQEKRKAAR | 
    800:
    KRSLEEEKIE | EEPKDNATIT | MCRMRARHWK | QISEIVGYDL | TPDSGTTLRK | 
    850:
    VLKLNLTPYL | EQFEVISAGA | SKEFSLEKAM | NTMIGTWEDI | AFHISLYRDT | 
    900:
    GVCILSSVDE | IQAILDDQII | KTQTMRGSPF | IKPFEHEIKA | WEDRLIRIQE | 
    950:
    TIDEWLKVQA | QWLYLEPIFC | SEDIMQQMPE | EGRQFQTVDR | HWRDIMKFCA | 
    1000:
    KDPKVLAATS | LTGLLEKLQN | CNELLEKIMK | GLNAYLEKKR | LFFPRFFFLS | 
    1050:
    NDEMLEILSE | TKDPLRVQPH | LKKCFEGIAK | LEFLPNLDIK | AMYSSEGERV | 
    1100:
    ELIALISTSA | ARGAVEKWLI | QVEDLMLRSV | HDVIAAARLA | YPESARRDWV | 
    1150:
    REWPGQVVLC | ISQMFWTSET | QEVISGGTEG | LKKYYKELQN | QLNEIVELVR | 
    1200:
    GKLSKQTRTT | LGALVTIDVH | ARDVVMDMIK | MGVSHDTDFL | WLAQLRYYWE | 
    1250:
    NENARVRIIN | CNVKYAYEYL | GNSPRLVITP | LTDRCYRTLI | GAFYLNLGGA | 
    1300:
    PEGPAGTGKT | ETTKDLAKAL | AVQCVVFNCS | DGLDYLAMGK | FFKGLASSGA | 
    1350:
    WACFDEFNRI | ELEVLSVVAQ | QILCIQRAIQ | QKLVVFVFEG | TELKLNPNCF | 
    1400:
    VAITMNPGYA | GRSELPDNLK | VLFRTVAMMV | PNYALIAEIS | LYSYGFLNAR | 
    1450:
    PLSVKIVMTY | RLCSEQLSSQ | FHYDYGMRAV | KAVLVAAGNL | KLKYPNENED | 
    1500:
    ILLLRSIKDV | NEPKFLSHDI | PLFNGITSDL | FPGIKLPEAD | YHEFLECAHE | 
    1550:
    ACNVHNLQPV | KFFLEKIIQT | YEMMIVRHGF | MLVGEPFAAK | TKVLHVLADT | 
    1600:
    LTLMNEHGYG | EEEKVIYRTV | NPKSITMGQL | FGQFDPVSHE | WTDGIVANTF | 
    1650:
    REFALSETPD | RKWVVFDGPI | DTLWIESMNT | VLDDNKKLCL | MSGEIIQMSP | 
    1700:
    QMSLIFETMD | LSQASPATVS | RCGMIYLEPS | QLGWEPLVSS | WLNSLKGPLC | 
    1750:
    EPEYQALLRG | LFAWLIPPSL | NQRVELFQLN | YLYTTIVSKI | LKILITFRIS | 
    1800:
    NYFKYVPLKT | QCTFIKFFLH | QQACFIFSLI | WSIGGSCDTD | GRRVFDTFIR | 
    1850:
    LIILGKDDEN | PVPDSVGKWE | CPFDEKGLVY | DYMYELKNKG | RWVHWNELIK | 
    1900:
    NTNLGDKQIK | IQDIIVPTMD | TIRYTFLMDL | SITYAKPLLF | VGPTGTGKSV | 
    1950:
    YVKDKLMNHL | EKDQYFPFYI | NLSARTSANQ | VQNIIMARLD | KRRKGVFGPP | 
    2000:
    MGKKCIIFID | DMNMPALEKY | GAQPPIELLR | QFFDCGHWYD | LKDTSKITLV | 
    2050:
    DIELIAAMGP | PGGGRNPVTP | RCIRHFNICS | INSFSDETMV | RIFSSIVAFY | 
    2100:
    LRTHEFPPEY | FVIGNQIVNG | TMEIYKQSVE | NLLPTPTKSH | YTFNLRDFSR | 
    2150:
    VIRGCLLIER | DAVANKHTMI | RLFVHEVLRV | FYDRLINDDD | RRWLFQLTKT | 
    2200:
    VIKDHFKESF | HSIFSHLRKQ | NAPVTEEDLR | NLMFGDYMNP | DLEGDDRVYI | 
    2250:
    EIPNIHHFSD | VVDQCLDEYN | QTHKTRMNLV | IFRYVLEHLS | RICRVLKQSG | 
    2300:
    GNALLVGLGG | SGRQSLTRLA | TSMAKMHIFQ | PEISKSYGMN | EWREDMKSFI | 
    2350:
    AVPVTNRIVD | NKSKILEKRL | RYLNDHFTYN | LYCNICRSLF | EKDKLLFSFL | 
    2400:
    LCANLLLARK | EIEYQELMFL | LTGGVSLKSA | EKNPDPTWLQ | DKSWEEICRA | 
    2450:
    SEFPAFRGLR | QHFCEHIYEW | REIYDSKEPH | NAKFPAPMDK | NLNELQKIII | 
    2500:
    LRCLRPDKIT | PAITNYVTDK | LGKKFVEPPP | FDLTKSYLDS | NCTIPLIFVL | 
    2550:
    SPGADPMASL | LKFANDKSMS | GNKFQAISLG | QGQGPIAAKM | IKAAIEEGTW | 
    2600:
    VCLQNCHLAV | SWMPMLEKIC | EDFTSETCNS | SFRLWLTSYP | SSKFPVTILQ | 
    2650:
    NGVKMTNEPP | TGLRLNLLQS | YLTDPVSDPE | FFKGCRGKEL | AWEKLLFGVC | 
    2700:
    FFHALVQERK | KFGPLGWNIP | YGFNESDLRI | SIRQLQLFIN | EYDTIPFEAI | 
    2750:
    SYLTGECNYG | GRVTDDWDRR | LLLTMLADFY | NLYIVENPHY | KFSPSGNYFA | 
    2800:
    PPKGTYEDYI | EFIKKLPFTQ | HPEIFGLHEN | VDISKDLQQT | KTLFESLLLT | 
    2850:
    QGGSKQTGAS | GSTDQILLEI | TKDILNKLPS | DFDIEMALRK | YPVRYEESMN | 
    2900:
    TVLVQEMERF | NNLIITIRNT | LRDLEKAIKG | VVVMDSALEA | LSGSLLVGKV | 
    2950:
    PEIWAKRSYP | SLKPLGSYIT | DFLARLNFLQ | DWYNSGKPCV | FWLSGFFFTQ | 
    3000:
    AFLTGAMQNY | ARKYTTPIDL | LGYEFEVIPS | DTSDTSPEDG | VYIHGLYLDG | 
    3050:
    ARWDRESGLL | AEQYPKLLFD | LMPIIWIKPT | QKSRIIKSDA | YVCPLYKTSE | 
    3092:
    RKGTLSTTGH | STNFVIAMLL | KTDQPTRHWI | KRGVALLCQL | DD
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
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    Related Databases
    SMR:
    MIM:
    String:
    Pfam:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Human Dynein heavy chain 12, axonemal
    ELISA Kit for Human Dynein heavy chain 12, axonemal
    ELISA Kit for Human Dynein heavy chain 12, axonemal
    ELISA Kit for Human Dynein heavy chain 12, axonemal
    CLIA Kit for Human Dynein heavy chain 12, axonemal
    CLIA Kit for Human Dynein heavy chain 12, axonemal
    CLIA Kit for Human Dynein heavy chain 12, axonemal
    CLIA Kit for Human Dynein heavy chain 12, axonemal
    Polyclonal Antibody for Human Dynein heavy chain 12, axonemal
    Polyclonal Antibody for Human Dynein heavy chain 12, axonemal
    Polyclonal Antibody for Human Dynein heavy chain 12, axonemal
    Polyclonal Antibody for Human Dynein heavy chain 12, axonemal
    Monoclonal Antibody for Human Dynein heavy chain 12, axonemal
    Monoclonal Antibody for Human Dynein heavy chain 12, axonemal
    Monoclonal Antibody for Human Dynein heavy chain 12, axonemal
    Monoclonal Antibody for Human Dynein heavy chain 12, axonemal
    Protein for Human Dynein heavy chain 12, axonemal
    Protein for Human Dynein heavy chain 12, axonemal
    Protein for Human Dynein heavy chain 12, axonemal
    Protein for Human Dynein heavy chain 12, axonemal

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    Precision
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    Linearity
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    References
    1. 1.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 2; 3 AND 4);VARIANTS ALA-32 AND SER-2893
      tissue: Testis.
      tissue: Trachea.
    2. 2.
      "The DNA sequence, annotation and analysis of human chromosome 3."
      Muzny D.M. , Scherer S.E. , Kaul R. , Wang J. , Yu J. , Sudbrak R. , Buhay C.J. , Chen R. , Cree A. , Ding Y. , Dugan-Rocha S. , Gill R. , Gunaratne P. , Harris R.A. , Hawes A.C. , Hernandez J. , Hodgson A.V. , Hume J. , more...
      Nature440:1194-1198(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    3. 3.
      "Mammalian cells express three distinct dynein heavy chains that are localized to different cytoplasmic organelles."
      Vaisberg E.A. , Grissom P.M. , McIntosh J.R.
      J. Cell Biol.133:831-842(1996) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 1116-1311 (ISOFORM 1)
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