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Index > Protein center > Dnah12(Gene name) > Rat
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  • Dnah12 (Gene name),
  • Dynein heavy chain 12, axonemal (Protein name ),  DYH12_RAT from NCBI database.
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  • Gene name:
    Dnah12;
    Protein name:
    Dynein heavy chain 12, axonemal;
    Alternative:
    Bm259;
    Organism:
    Rat (Rattus norvegicus). 
    General Annotation
    Sub Unit:
    Consists of at least two heavy chains and a number of intermediate and light chains.
    Function:
    Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP. Involved in sperm motility; implicated in sperm flagellar assembly.
    Subcellular Location:
    Cytoplasm cytoskeleton cilium axoneme
    Protein Attributes:
    Sequence length:
    3092
    Sequence:
    50:
    MSDPNKTAIT | AEKEALNLKL | PPIVHPPKNI | GVDTPKQSEL | LNYRRSKEQQ | 
    100:
    KKINQLVISA | AKKSLDKTLD | KRIPPLPEPD | FPPTMTSEIK | KKGLNYIFMK | 
    150:
    QCVESSPIVP | IQPQWLDHML | MLIPEHLKEG | KKREELLGSL | INEVSMDFEK | 
    200:
    SMKRYLVQSV | LVKPPVKWLE | DEWGPLPESP | EGLDYSNPWH | SNFVQARSQI | 
    250:
    LANLHIVHPT | MKLLLELGYT | TFSDIILLDL | TGIRDRGPID | CEALRNDLSI | 
    300:
    QARKAEERIM | NTWYPKVINL | FTKKEALEGI | KPEKVDSFYN | CVSILMSNQL | 
    350:
    KDLLWRTVEE | FVRLFDSRYI | LRLPIFKMEL | TFDDDKMEFY | PTFQDLEDVV | 
    400:
    LGLIERISET | LQTVQTVPSW | LSGTTAPVNL | DTELPEHVMY | WALSTLRIAV | 
    450:
    HQNLEGVRAH | YKTYVTNYNW | LLDGTATKMI | ERFQSENHTF | DEYTEFIERF | 
    500:
    FSLASEIMLL | PQWAHYPMVR | LDCEDLKTGL | TNKAKAFANI | LLNDIASKHR | 
    550:
    KENESICSEF | ETIKEHALRV | PETTEEMMEL | IAFIEKARTT | GIQNLAQRIQ | 
    600:
    ESKRQMGYFL | DTFLLSQEDL | NLNASVLLWP | SKINPVFDEN | DELIENSKRT | 
    650:
    KENELIAKRE | KLILEIEKES | RRMEEFTEFA | ELDRMQQYVA | DVRHLQKRIQ | 
    700:
    DSEEAVQFIN | KEEELFKWEL | TKYPELEKLK | VTIEPYQKFF | NFVLKWQRTE | 
    750:
    KRWMDGGFLD | LNGESMEADI | DEFSREVFKT | LKFFQTKQKK | ELQEKRKAAR | 
    800:
    KRSLMEEKPE | EEPKESPTIT | MMRARHWKQM | SEIVGYDLTP | DSGTTLRKVL | 
    850:
    KLNLTPYLES | FEVISAGASK | EFSLERAMNA | MIATWDDISF | HISLYRDTGV | 
    900:
    YILSSVDEIQ | AILDDQIIKT | QTMRGSPFIK | PFENEIKAWE | DRLIRIQETI | 
    950:
    DEWLKVQAQW | LYLEPIFCSE | DIMQQMPEEG | RQFQTVDRHW | KDIMKFCAKD | 
    1000:
    PKVLAATSLT | GLLEKLQNCN | DLLDKIMKGL | NAYLEKKRLF | FPRFFFLSND | 
    1050:
    EMLEILSETK | DPLRVQPHLK | KCFEGIAKLE | FLTNLDIKAM | YSSEGERVEL | 
    1100:
    ISVISTSAAR | GAVEKWLIQV | EDLMLRSIHD | VIAASRLAYP | ESARKDWVRE | 
    1150:
    WPGQVVLCVS | QMFWTSETQE | VISGGNEGLK | KYYKELQYQL | NDIVELVRGK | 
    1200:
    LSKQTRITLG | ALVTIDVHAR | DVVMDMIDMG | VSHDTDFQWL | AQLRYYWEYE | 
    1250:
    NARVRIVNCN | VKYAYEYLGN | SPRLVITPLT | DRCYRTLIGA | FYLNLGGAPE | 
    1300:
    GPAGTGKTET | TKDLAKALAV | QCVVFNCSDG | LDYLAMGKFF | KGLASSGAWA | 
    1350:
    CFDEFNRIEL | EVLSVVAQQI | LCIQRAIQQK | LEVFVFEGTE | LRLNPNCFVA | 
    1400:
    ITMNPGYAGR | SELPDNLKVL | FRTVAMMVPN | YALIAEISLY | SYGFLNAKPL | 
    1450:
    SVKIVMTYRL | CSEQLSSQFH | YDYGMRAVKA | VLVAAGNLKL | KYPNENEDIL | 
    1500:
    LLRSIKDVNE | PKFLSHDIPL | FNGITSDLFP | GIKLPEADYQ | EFLECAYEAC | 
    1550:
    ETQNLQPVKF | FLEKIIQTYE | MMIVRHGFML | VGEPFAAKTE | VLHILADTLT | 
    1600:
    LMNERNYGDE | EKVMYRTVNP | KSITMGQLFG | QFDPVSHEWT | DGIVANTFRE | 
    1650:
    FALAESPDRK | WVVFDGPIDT | LWIESMNTVL | DDNKKLCLMS | GEIIQMSPQM | 
    1700:
    SLIFETMDLS | QASPATVSRC | GMIYLEPSQL | GWEPIVASWL | NSLKEPLNEL | 
    1750:
    EHQNLLKELF | NWLVQPSLEF | RRKKCKVTAH | RVWLFPTVYS | SWVCLILFVL | 
    1800:
    EVSAVSPKCS | LKSNCYNLFH | QQATFVFSLI | WSVGASCDTD | GRLAFDNFLR | 
    1850:
    SLVTGKNDKA | PMPVFINKWE | CPFDEKGLVY | DYMYELRNRG | RWIHWNDLIK | 
    1900:
    SSDIEDRRTK | IQDIIVPTMD | TIRYTFLMDL | CISHAKPLLF | VGPTGTGKSV | 
    1950:
    YVKDKLMNHL | EKGKYFPFYV | NFSARTSANQ | VQNIIMARLD | KRRKGVFGPP | 
    2000:
    MGKKCVVFID | DMNMPSLEKY | GAQPPIELLR | QFFDCGHWYD | LKDTTKITLV | 
    2050:
    DIELIAAMGP | PGGGRNAVTP | RFIRHFNICT | INSFSDETMV | RIFSSIMMFY | 
    2100:
    LRTHDFSPEY | FVLGHQIVSA | TMEIYKQSMG | NLLPTPAKSH | YTFNLRDFSR | 
    2150:
    VIRGCLLIDK | EAIESKHTMI | RLFVHEVLRV | FYDRLINDED | RNWLFLLIKN | 
    2200:
    VIKDHFKESL | ENVFSHLRRG | NSSINEEDLR | NLMFGDYMNP | DLEGDDRVYI | 
    2250:
    EILNIHQFNE | VVDQCLDEYN | QTHKRRMNLV | VFRYVLEHLS | RICRILKQSG | 
    2300:
    GNALLIGLGG | SGRQSLTSLA | TSMAKMQIFQ | PEISKSYGMN | EWREDIKPNL | 
    2350:
    MSVFYATSIR | DNLSKILEKR | LRYLNDHFTY | NLYCNICRSL | FEKDKLLFSF | 
    2400:
    LLCANLLLAK | KEIEYQELMF | LLTGGVSLKS | AEKNPDPNWL | QDKSWEEICR | 
    2450:
    ASELPVFHGL | REHFCNHIRE | WEDIYNSKEP | HNMKLPESMD | KTLNELQKII | 
    2500:
    ILRCLRPDKI | TPAITNYVTD | KLGKKFVEPP | PFDLTKSYLD | SNCTIPLIFV | 
    2550:
    LSPGADPMAS | LLKFANDKSM | SGNKFQAISL | GQGQGPVATK | MITAAIEEGT | 
    2600:
    WVCLQNCHLA | VSWMPTLEKI | CEDFSPEICN | PTFRLWLTSY | PSPKFPVTIL | 
    2650:
    QNGVKMTNEP | PTGLRLNLLQ | SYLSDPISDP | EFFNGCPGKE | LAWEKLLFGV | 
    2700:
    CFFHALVQER | KKFGPLGWNI | PYGFNESDLR | ISIRQLQLFI | NEYDTIPFEA | 
    2750:
    ISYLTGECNY | GGRVTDDWDR | RLLLTMLADF | YNSLIIENPH | YKFSPSGNYF | 
    2800:
    APPKGTYDEY | IEFIKKLPFT | QEPEIFGLHE | NVDISKDLQQ | TKLLFESLLL | 
    2850:
    TQGGVKQTGS | SGSTDQILLE | ITEDILTQLP | NDFDIEAALR | SYPVRYEESM | 
    2900:
    NTVLVQEMER | FNNLIITIRN | TLRDLKKAIK | GVVVMDSALE | ALSGSLLIGK | 
    2950:
    VPEMWAQRSY | PSLKPLGSYI | TDFLTRLKFL | EDWFTMGKPN | VFWISGFFFT | 
    3000:
    QAFLTGAMQN | YARKYTIPID | LLGYEFEVIP | SDNATNPPED | GVYIHGLYLD | 
    3050:
    GARWNRTSGL | LAEQHPKLLF | DLMPIIWIKP | NVKTEIVKTD | AYVCPLYKTS | 
    3092:
    ERKGTLSTTG | HSTNFVIAML | LRTELPAQHW | IKRGVALLCQ | LD
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
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    Related Databases
    UniGene:
    Pfam:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Rat Dynein heavy chain 12, axonemal
    ELISA Kit for Rat Dynein heavy chain 12, axonemal
    ELISA Kit for Rat Dynein heavy chain 12, axonemal
    ELISA Kit for Rat Dynein heavy chain 12, axonemal
    CLIA Kit for Rat Dynein heavy chain 12, axonemal
    CLIA Kit for Rat Dynein heavy chain 12, axonemal
    CLIA Kit for Rat Dynein heavy chain 12, axonemal
    CLIA Kit for Rat Dynein heavy chain 12, axonemal
    Polyclonal Antibody for Rat Dynein heavy chain 12, axonemal
    Polyclonal Antibody for Rat Dynein heavy chain 12, axonemal
    Polyclonal Antibody for Rat Dynein heavy chain 12, axonemal
    Polyclonal Antibody for Rat Dynein heavy chain 12, axonemal
    Monoclonal Antibody for Rat Dynein heavy chain 12, axonemal
    Monoclonal Antibody for Rat Dynein heavy chain 12, axonemal
    Monoclonal Antibody for Rat Dynein heavy chain 12, axonemal
    Monoclonal Antibody for Rat Dynein heavy chain 12, axonemal
    Protein for Rat Dynein heavy chain 12, axonemal
    Protein for Rat Dynein heavy chain 12, axonemal
    Protein for Rat Dynein heavy chain 12, axonemal
    Protein for Rat Dynein heavy chain 12, axonemal

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    References
    1. 1.
      "Genome sequence of the Brown Norway rat yields insights into mammalian evolution."
      Gibbs R.A. , Weinstock G.M. , Metzker M.L. , Muzny D.M. , Sodergren E.J. , Scherer S. , Scott G. , Steffen D. , Worley K.C. , Burch P.E. , Okwuonu G. , Hines S. , Lewis L. , Deramo C. , Delgado O. , Dugan-Rocha S. , Miner G. , Morgan M. , more...
      Nature428:493-521(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
      strain: Brown Norway.
    2. 2.
      "Altered gene expression in cerebral capillaries of stroke-prone spontaneously hypertensive rats."
      Kirsch T. , Wellner M. , Luft F.C. , Haller H. , Lippoldt A.
      Brain Res.910:106-115(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 600-736
      strain: SHRSP.
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