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Index > Protein center > DNAH7(Gene name) > Human
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  • DNAH7 (Gene name),
  • Dynein heavy chain 7, axonemal (Protein name ),  DYH7_HUMAN from NCBI database.
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  • Gene name:
    DNAH7(KIAA0944);
    Protein name:
    Dynein heavy chain 7, axonemal;
    Alternative:
    Ciliary dynein heavy chain 7;Axonemal beta dynein heavy chain 7;hDHC2;Dynein heavy chain-like protein 2;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    The dynein complex consists of at least two heavy chains and a number of intermediate and light chains.
    Function:
    Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP.
    Subcellular Location:
    Cytoplasm cytoskeleton cilium axoneme
    Protein Attributes:
    Sequence length:
    4024
    Sequence:
    50:
    MSSEQDKSAS | KEKSKKPVRF | LPQLSMEKLA | SKEKFKAPAR | ALPQLSMVST | 
    100:
    KPHWQQAAPS | FHLSVKQDDE | SPEPFSVKNE | QSHAEYMERF | GKKGKLPHQV | 
    150:
    DDSYVGPSTS | KSKGKSPHKE | RENFRSTLVN | VIMQQDADLD | SAVPDGSTIP | 
    200:
    KPTASAIEKD | ILRYYYYIHH | GIDTDHVAPM | EDSWLEHVLD | LVPQHLKVFT | 
    250:
    DSIVTLSDEM | REDYLLSVRK | SIVDFVLKDP | REKGDDKKTD | ELPAHRAEME | 
    300:
    ILPKPWRKSF | LAASSYIRDH | LNAMNPTMLA | VLDLWHTNFK | KLRLVDIKEF | 
    350:
    HNCQDALELS | SFQNIIMRHM | DSAKETLLKM | WFPEVQNIYY | QGNKKKQLPT | 
    400:
    GDSSAKLESF | FNCAAALMTL | QLQDLTLVSM | QDFTDLIAQP | PDSVRAFEHP | 
    450:
    GFIMRLILDN | DTIKFEPELS | DYIDIFLNVY | DVMIKAVSFV | PRVETKLYSK | 
    500:
    WESKSKPTTL | KPIILNEIVD | AHKEKIKEVI | MKESVAPTEH | LRLYDKYDFL | 
    550:
    ITRKAERDVD | NFLAENHSYE | KIIDEICKYQ | KLIEEIQYTS | IKTIRLGMFE | 
    600:
    MHCEELIRAL | VKRADIICGK | LLAKMFRDHQ | EVNTRLCDEF | ERIAEKALST | 
    650:
    PPNTAELMEM | KAYIQKVEVT | DMIELEQRLV | DSKNCLAFLI | EYVNFSPADM | 
    700:
    RLNNSVFQWY | GRMGEIFEEH | RKIIKEKIEQ | YQEGLKLRCE | RFVEELESYA | 
    750:
    KQSEEFYSFG | DLQDVQRYLK | KAQILNGKLD | LAADKIEQFN | AEEEAFGWLP | 
    800:
    SVYPQRKKIQ | DGLNPYLRLY | ETAVEFSSNY | RAWTEGPYHK | VNPDQVEADI | 
    850:
    GNYWRGLYKL | EKTFHDSPYA | LAMTKKVRSK | VEDFKQHIPL | IQVICNPGLR | 
    900:
    PRHWEAMSAI | VGYPLQPSDD | STVSSFLDMN | LEPYIDRFEG | ISEAASKEYS | 
    950:
    LEKAMEKMIT | EWDAVEFVIH | SYRETGTFIL | ASVDEIQMLL | DDHIIKTQTM | 
    1000:
    RGSPFIKPYE | KQMREWEGKL | LLLQEILDEW | LKVQATWLYL | EPIFSSPDIM | 
    1050:
    SQMPEEGRRF | TAVDKTWRDI | MRSVMQDKHV | LTVVTIDRML | ERLKKSNELL | 
    1100:
    ELILKGLNEY | LEKKRLFFPR | FFFLSNDELL | EILSETKDPT | RVQPHLKKCF | 
    1150:
    EGIAKVEFTE | TLDITHMKSS | EGEVVELIEI | ISTAKARGQV | EKWLVELERV | 
    1200:
    MINSIHKVTG | DATFAYTKYE | RINWVRDWPG | QTVLCVSQIF | WTKEVQTAIP | 
    1250:
    MGIKALEQYL | KTCNRQIDDI | VTLVRGKLSM | QNRVTLGALV | VLDVHARDVL | 
    1300:
    SSLVKKNISD | DSDFEWLSQL | RYYWQENHLE | TKMINAGLRY | GYEYLGNSPR | 
    1350:
    LVITPLTDRC | YRTLFGALHL | HLGGAPEGPA | GTGKTETTKD | LAKAVAKQCV | 
    1400:
    VFNCSDGLDY | LALGKFFKGL | LSCGAWACFD | EFNRIDLEVL | SVVAQQILTI | 
    1450:
    QRGINAGADI | LMFEGTELKL | DPTCAVFITM | NPGYAGRSEL | PDNLKALFRT | 
    1500:
    VAMMVPDYAM | IAEIVLYSCG | FVTARPLSVK | IVATYRLCSE | QLSSQHHYDY | 
    1550:
    GMRAVKSVLT | AAGNLKLKYP | NENEEILLLR | SIIDVNLPKF | LSHDLPLFEG | 
    1600:
    ITSDLFPGVK | LPKPDYNDLL | AAIKDNCASM | NLQMTAFFSE | KILQVYEMMI | 
    1650:
    VRHGFMIVGE | PFGGKTSAYR | VLAGALNDIC | EKGLMEENKV | QITVLNPKSV | 
    1700:
    TMGQLYGQFD | SVSHEWSDGV | LAVSFRAFAS | SVTPDRKWLI | FDGPVDAVWI | 
    1750:
    ENMNTVLDDN | KKLCLMSGEI | IQMSPQMNLI | FEPMDLEVAS | PATVSRCGMI | 
    1800:
    YMEPHMLGWR | PLMLSWVNLL | PASVSVIQKE | FIMGLFDRMV | PVSVEFIRKH | 
    1850:
    TKELSPTSDT | NLVRSLMNLI | DCFMDDFADE | VKLKERNDRE | TYSLLEGIFL | 
    1900:
    FSLIWSVGAS | CTDDDRLKFN | KILRELMESP | ISDRTRNTFK | LQSGTEQTSS | 
    1950:
    KALTVPFPEK | GTIYDYQFVT | EGIGKWEPWI | KKLKEAPPIP | KDVMFNEIIV | 
    2000:
    PTLDTIRYSA | LMELLTTHQK | PSIFVGPTGT | GKSVYITNFL | LNQLNKEIYK | 
    2050:
    PLLINFSAQT | TAAQTQNIVM | SKLDKRRKGV | FGPPLGKRMV | VFVDDVNMPA | 
    2100:
    REVYGAQPPI | ELLRQWLDHW | NWYDLKDCSM | IKLVDIQIMC | AMGPPGGGRN | 
    2150:
    PVTPRYMRHF | NIITINEFSD | KSMYTIFSRI | LTWHLEICYK | FPDEFLDLTT | 
    2200:
    QIVNGTMTLY | KEAMKNLLPT | PAKSHYLFNL | RDFSRVIQGV | CLSRPETTET | 
    2250:
    TEVIKRLWVH | EVLRVYYDRL | LDNTDRSWLI | NYIQEILRNY | MYEDFHELFQ | 
    2300:
    RLDFDNDGMV | EADDLRSLMF | CDFHDPKRED | TNYREIADVD | NLRMIVEIHL | 
    2350:
    EEYNNISKKP | MNLVLFRFAI | EHISRISRIL | KQPRSHALLV | GVGGSGRQSV | 
    2400:
    TRLAAHMADY | SVFQVEISKG | YDTTEWHEDL | KVILRKCAEG | EMQGVFLFTD | 
    2450:
    TQIKEESFLE | DVSNLLNAGE | IPNLFALDEK | QEICDKMRQL | DRQRDKTKQT | 
    2500:
    DGSPIALFNM | FIDHCRSQLH | VVLAMSPIGD | AFRNRLRKFP | ALVNCCTIDW | 
    2550:
    FQSWPEDALQ | AVASRFLEEI | EMSEEIRDGC | IDMCKSFHTS | TIDLSKSFFV | 
    2600:
    ELQRYNYVTP | TSYLELISTF | KLLLEKKRSE | VMKMKKRYEV | GLEKLDSASS | 
    2650:
    QVATMQMELE | ALHPQLKVAS | KEVDEMMIMI | EKESVEVAKT | EKIVKADETI | 
    2700:
    ANEQAMASKA | IKDECDADLA | GALPILESAL | AALDTLTAQD | ITVVKSMKSP | 
    2750:
    PAGVKLVMEA | ICILKGIKAD | KIPDPTGSGK | KIEDFWGPAK | RLLGDMRFLQ | 
    2800:
    SLHEYDKDNI | PPAYMNIIRK | NYIPNPDFVP | EKIRNASTAA | EGLCKWVIAM | 
    2850:
    DSYDKVAKIV | APKKIKLAAA | EGELKIAMDG | LRKKQAALKE | VQDKLARLQD | 
    2900:
    TLELNKQKKA | DLENQVDLCS | KKLERAEQLI | GGLGGEKTRW | SHTALELGQL | 
    2950:
    YINLTGDILI | SSGVVAYLGA | FTSTYRQNQT | KEWTTLCKGR | DIPCSDDCSL | 
    3000:
    MGTLGEAVTI | RTWNIAGLPS | DSFSIDNGII | IMNARRWPLM | IDPQSQANKW | 
    3050:
    IKNMEKANSL | YVIKLSEPDY | VRTLENCIQF | GTPVLLENVG | EELDPILEPL | 
    3100:
    LLKQTFKQGG | STCIRLGDST | IEYAPDFRFY | ITTKLRNPHY | LPETSVKVTL | 
    3150:
    LNFMITPEGM | QDQLLGIVVA | QERPDLEEEK | QALILQGAEN | KRQLKEIEDK | 
    3200:
    ILEVLSSSEG | NILEDETAIK | ILSSSKALAN | EISQKQEVAE | ETEKKIDTTR | 
    3250:
    MGYRPIAIHS | SILFFSLADL | ANIEPMYQYS | LTWFINLFIL | SIENSEKSEI | 
    3300:
    LAKRLQILKD | HFTYSLYVNV | CRSLFEKDKL | LFSFCLTINL | LLHERAINKA | 
    3350:
    EWRFLLTGGI | GLDNPYANLC | TWLPQKSWDE | ICRLDDLPAF | KTIRREFMRL | 
    3400:
    KDGWKKVYDS | LEPHHEVFPE | EWEDKANEFQ | RMLIIRCLRP | DKVIPMLQEF | 
    3450:
    IINRLGRAFI | EPPPFDLAKA | FGDSNCCAPL | IFVLSPGADP | MAALLKFADD | 
    3500:
    QGYGGSKLSS | LSLGQGQGPI | AMKMLEKAVK | EGTWVVLQNC | HLATSWMPTL | 
    3550:
    EKVCEELSPE | STHPDFRMWL | TSYPSPNFPV | SVLQNGVKMT | NEAPKGLRAN | 
    3600:
    IIRSYLMDPI | SDPEFFGSCK | KPEEFKKLLY | GLCFFHALVQ | ERRKFGPLGW | 
    3650:
    NIPYEFNETD | LRISVQQLHM | FLNQYEELPY | EALRYMTGEC | NYGGRVTDDW | 
    3700:
    DRRTLRSILN | KFFNPELVEN | SDYKFDSSGI | YFVPPSGDHK | SYIEYTKTLP | 
    3750:
    LTPAPEIFGM | NANADITKDQ | SETQLLFDNI | LLTQSRSAGA | GAKSSDEVVN | 
    3800:
    EVASDILGKL | PNNFDIEAAM | RRYPTTYTQS | MNTVLVQEMG | RFNKLLKTIR | 
    3850:
    DSCVNIQKAI | KGLAVMSTDL | EEVVSSILNV | KIPEMWMGKS | YPSLKPLGSY | 
    3900:
    VNDFLARLKF | LQQWYEVGPP | PVFWLSGFFF | TQAFLTGAQQ | NYARKYTIPI | 
    3950:
    DLLGFDYEVM | EDKEYKHPPE | DGVFIHGLFL | DGASWNRKIK | KLAESHPKIL | 
    4000:
    YDTVPVMWLK | PCKRADIPKR | PSYVAPLYKT | SERRGVLSTT | GHSTNFVIAM | 
    4024:
    TLPSDQPKEH | WIGRGVALLC | QLNS
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
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    Related Databases
    UniGene:
    KEGG:
    MIM:
    String:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Human Dynein heavy chain 7, axonemal
    ELISA Kit for Human Dynein heavy chain 7, axonemal
    CLIA Kit for Human Dynein heavy chain 7, axonemal
    CLIA Kit for Human Dynein heavy chain 7, axonemal
    Polyclonal Antibody for Human Dynein heavy chain 7, axonemal
    Polyclonal Antibody for Human Dynein heavy chain 7, axonemal
    Monoclonal Antibody for Human Dynein heavy chain 7, axonemal
    Monoclonal Antibody for Human Dynein heavy chain 7, axonemal
    Protein for Human Dynein heavy chain 7, axonemal
    Protein for Human Dynein heavy chain 7, axonemal

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    References
    1. 1.
      "Identification of dynein heavy chain 7 as an inner arm component of human cilia that is synthesized but not assembled in a case of primary ciliary dyskinesia."
      Zhang Y.J. , O'Neal W.K. , Randell S.H. , Blackburn K. , Moyer M.B. , Boucher R.C. , Ostrowski L.E.
      J. Biol. Chem.277:17906-17915(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);IDENTIFICATION BY MASS SPECTROMETRY;SUBCELLULAR LOCATION;INDUCTION;TISSUE SPECIFICITY;VARIANT PRO-3319
      tissue: Tracheobronchial epithelium.
    2. 2.
      "Prediction of the coding sequences of unidentified human genes. XIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro."
      Nagase T. , Ishikawa K. , Suyama M. , Kikuno R. , Hirosawa M. , Miyajima N. , Tanaka A. , Kotani H. , Nomura N. , Ohara O.
      DNA Res.6:63-70(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1);VARIANTS CYS-545 AND PRO-3319
      tissue: Brain.
    3. 3.
      Nagase T. , Kikuno R. , Yamakawa H. , Ohara O.
      Submitted (2003-01) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SEQUENCE REVISION
    4. 4.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 4)
      tissue: Brain cortex.
    5. 5.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 3)
      tissue: Fetal kidney.
    6. 6.
      "Generation and annotation of the DNA sequences of human chromosomes 2 and 4."
      Hillier L.W. , Graves T.A. , Fulton R.S. , Fulton L.A. , Pepin K.H. , Minx P. , Wagner-McPherson C. , Layman D. , Wylie K. , Sekhon M. , Becker M.C. , Fewell G.A. , Delehaunty K.D. , Miner T.L. , Nash W.E. , Kremitzki C. , Oddy L. , Du H. , more...
      Nature434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    7. 7.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)
      tissue: Testis.
    8. 8.
      "Identification, tissue specific expression, and chromosomal localisation of several human dynein heavy chain genes."
      Maiti A.K. , Mattei M.-G. , Jorissen M. , Volz A. , Zeigler A. , Bouvagnet P.
      Eur. J. Hum. Genet.8:923-932(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 1290-1432 (ISOFORM 1);NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1356-1422 (ISOFORM 1);TISSUE SPECIFICITY
      tissue: Nasal polyp.
    9. 9.
      "Identification of dynein heavy chain genes expressed in human and mouse testis: chromosomal localization of an axonemal dynein gene."
      Neesen J. , Koehler M.R. , Kirschner R. , Steinlein C. , Kreutzberger J. , Engel W. , Schmid M.
      Gene200:193-202(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 1333-1503 (ISOFORM 1)
      tissue: Testis.
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