Dyrk1a ELISA Kit for Rat(Rattus norvegicus) | EIAab.comDyrk1a ELISA Kit for Rat(Rattus norvegicus)

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Index > Protein center > Dyrk1a(Gene name) > Rat

Dyrk1a (Gene name),

Dual specificity tyrosine-phosphorylation-regulated kinase 1A (Protein name ), DYR1A_RAT from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Dyrk1a(Dyrk);

Protein name:

Dual specificity tyrosine-phosphorylation-regulated kinase 1A;

Alternative:

Protein kinase minibrain homolog(MNBH);Dual specificity YAK1-related kinase;RP86;

Organism:

Rat (Rattus norvegicus).

General Annotation

Sub Unit:

Interacts with RANBP9. Interacts with RAD54L2/ARIP4 (By similarity). Interacts with WDR68.

Function:

May play a role in a signaling pathway regulating nuclear functions of cell proliferation. Phosphorylates serine, threonine and tyrosine residues in its sequence and in exogenous substrates.

Subcellular Location:

Nucleus speckle

Protein Attributes:

Sequence length:

763

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

500:

550:

600:

650:

700:

750:

763:

TGVCVQQSPV | ASS

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

UniGene:

Rn.9354

String:

Q63470

STRING:

10116.ENSRNOP00000042446

KEGG:

rno:25255

Pfam:

PF00069

Uniprot:

Q63470

FOR

ELISA Kit for Rat Dual specificity tyrosine-phosphorylation-regulated kinase 1A

CLIA Kit for Rat Dual specificity tyrosine-phosphorylation-regulated kinase 1A

Polyclonal Antibody for Rat Dual specificity tyrosine-phosphorylation-regulated kinase 1A

Monoclonal Antibody for Rat Dual specificity tyrosine-phosphorylation-regulated kinase 1A

Protein for Rat Dual specificity tyrosine-phosphorylation-regulated kinase 1A

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Dyrk, a dual specificity protein kinase with unique structural features whose activity is dependent on tyrosine residues between subdomains VII and VIII."
Kentrup H. , Becker W. , Heukelbach J. , Wilmes A. , Schuermann A. , Huppertz C. , Kainulainen H. , Joost H.-G.
J. Biol. Chem.271:3488-3495(1996) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM LONG);FUNCTION;TISSUE SPECIFICITY;PHOSPHORYLATION AT TYR-219; TYR-319 AND TYR-321;MUTAGENESIS OF LYS-188; TYR-219; TYR-319 AND TYR-321
strain: Sprague-Dawley.
tissue: Brain.
2.

Kentrup H.
Submitted (1997-10) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SEQUENCE REVISION
3.

"Sequence characteristics, subcellular localization, and substrate specificity of DYRK-related kinases, a novel family of dual specificity protein kinases."
Becker W. , Weber Y. , Wetzel K. , Eirmbter K. , Tejedor F.J. , Joost H.-G.
J. Biol. Chem.273:25893-25902(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;TISSUE SPECIFICITY;SUBCELLULAR LOCATION
4.

"Dual-specificity tyrosine phosphorylation-regulated kinase 1A (Dyrk1A) modulates serine/arginine-rich protein 55 (SRp55)-promoted Tau exon 10 inclusion."
Yin X. , Jin N. , Gu J. , Shi J. , Zhou J. , Gong C.X. , Iqbal K. , Grundke-Iqbal I. , Liu F.
J. Biol. Chem.287:30497-30506(2012) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION;INTERACTION WITH SRSF6;FUNCTION;MUTAGENESIS OF LYS-188;TISSUE SPECIFICITY
5.

"Selectivity, cocrystal structures, and neuroprotective properties of leucettines, a family of protein kinase inhibitors derived from the marine sponge alkaloid leucettamine B."
Tahtouh T. , Elkins J.M. , Filippakopoulos P. , Soundararajan M. , Burgy G. , Durieu E. , Cochet C. , Schmid R.S. , Lo D.C. , Delhommel F. , Oberholzer A.E. , Pearl L.H. , Carreaux F. , Bazureau J.P. , Knapp S. , Meijer L.
J. Med. Chem.55:9312-9330(2012) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: CATALYTIC ACTIVITY;ENZYME REGULATION;TISSUE SPECIFICITY

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