Protein name:
Transcription factor E2F5 (E2F-5) ;
Alternative:
Organism:
Mouse (Mus musculus).
General Annotation
Sub Unit:
Component of the DRTF1/E2F transcription factor complex. Binds cooperatively with DP-1 to E2F sites. Interaction with retinoblastoma protein RB1 or proteins RBL1 and RBL2 inhibits the E2F transactivation domain. Component of the DREAM complex (also named LINC complex) at least composed of E2F4, E2F5, LIN9, LIN37, LIN52, LIN54, MYBL1, MYBL2, RBL1, RBL2, RBBP4, TFDP1 and TFDP2. The complex exists in quiescent cells where it represses cell cycle-dependent genes. It dissociates in S phase when LIN9, LIN37, LIN52 and LIN54 form a subcomplex that binds to MYBL2.
Function:
Transcriptional activator that binds to E2F sites, these sites are present in the promoter of many genes whose products are involved in cell proliferation. May mediate growth factor-initiated signal transduction.
Subcellular Location:
Nucleus
Protein Attributes:
50:
MAAAEPTSSA | QPTPQAQAQP | PPHGAPSSQP | SAALAGGSSR | HEKSLGLLTT |
100:
KFVSLLQEAQ | DGVLDLKAAA | DTLAVRQKRR | IYDITNVLEG | IDLIEKKSKN |
150:
SIQWKGVGAG | CNTKEVIDRL | RCLKAEIEDL | ELKERELDQQ | KLWLQQSIKN |
200:
VMEDSINNRF | SYVTHEDICN | CFHGDTLLAI | QAPSGTQLEV | PIPEMGQNGQ |
250:
KKYQINLKSH | SGPIHVLLIN | KESSSSKPVV | FPVPPPDDLT | QPSSQSSTSV |
300:
TPQKSTMAAQ | NLPEQHVSER | SQTFQQTPAA | EVSSGSISGD | IIDELMSSDV |
335:
FPLLRLSPTP | ADDYNFNLDD | NEGVCDLFDV | QILNY
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Rat
Mouse
ELISA Kit for Mouse E2F-5
ELISA Kit for Mouse E2F-5
ELISA Kit for Mouse E2F-5
Polyclonal Antibody for Mouse E2F-5
Polyclonal Antibody for Mouse E2F-5
Polyclonal Antibody for Mouse E2F-5
Monoclonal Antibody for Mouse E2F-5
Monoclonal Antibody for Mouse E2F-5
Monoclonal Antibody for Mouse E2F-5
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
2.
"The transcriptional landscape of the mammalian genome."
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Science309:1559-1563(2005)
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[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
strain :
NOD .
tissue :
Spleen .
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
strain :
FVB/N .
tissue :
Mammary tumor .
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : DEVELOPMENTAL STAGE
5.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : DEVELOPMENTAL STAGE