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Index > Protein center > E2f5(Gene name) > Mouse
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  • E2f5 (Gene name),
  • Transcription factor E2F5 (Protein name ),  E2F5_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    E2f5;
    Protein name:
    Transcription factor E2F5(E2F-5);
    Alternative:

    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Component of the DRTF1/E2F transcription factor complex. Binds cooperatively with DP-1 to E2F sites. Interaction with retinoblastoma protein RB1 or proteins RBL1 and RBL2 inhibits the E2F transactivation domain. Component of the DREAM complex (also named LINC complex) at least composed of E2F4, E2F5, LIN9, LIN37, LIN52, LIN54, MYBL1, MYBL2, RBL1, RBL2, RBBP4, TFDP1 and TFDP2. The complex exists in quiescent cells where it represses cell cycle-dependent genes. It dissociates in S phase when LIN9, LIN37, LIN52 and LIN54 form a subcomplex that binds to MYBL2.
    Function:
    Transcriptional activator that binds to E2F sites, these sites are present in the promoter of many genes whose products are involved in cell proliferation. May mediate growth factor-initiated signal transduction.
    Subcellular Location:
    Nucleus
    Protein Attributes:
    Sequence length:
    335
    Sequence:
    50:
    MAAAEPTSSA | QPTPQAQAQP | PPHGAPSSQP | SAALAGGSSR | HEKSLGLLTT | 
    100:
    KFVSLLQEAQ | DGVLDLKAAA | DTLAVRQKRR | IYDITNVLEG | IDLIEKKSKN | 
    150:
    SIQWKGVGAG | CNTKEVIDRL | RCLKAEIEDL | ELKERELDQQ | KLWLQQSIKN | 
    200:
    VMEDSINNRF | SYVTHEDICN | CFHGDTLLAI | QAPSGTQLEV | PIPEMGQNGQ | 
    250:
    KKYQINLKSH | SGPIHVLLIN | KESSSSKPVV | FPVPPPDDLT | QPSSQSSTSV | 
    300:
    TPQKSTMAAQ | NLPEQHVSER | SQTFQQTPAA | EVSSGSISGD | IIDELMSSDV | 
    335:
    FPLLRLSPTP | ADDYNFNLDD | NEGVCDLFDV | QILNY
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    String:
    Pfam:
    KEGG:
    UniGene:
    SMR:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse E2F-5
    ELISA Kit for Mouse E2F-5
    ELISA Kit for Mouse E2F-5
    CLIA Kit for Mouse E2F-5
    CLIA Kit for Mouse E2F-5
    CLIA Kit for Mouse E2F-5
    Polyclonal Antibody for Mouse E2F-5
    Polyclonal Antibody for Mouse E2F-5
    Polyclonal Antibody for Mouse E2F-5
    Monoclonal Antibody for Mouse E2F-5
    Monoclonal Antibody for Mouse E2F-5
    Monoclonal Antibody for Mouse E2F-5
    Protein for Mouse E2F-5
    Protein for Mouse E2F-5
    Protein for Mouse E2F-5

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Molecular and functional characterisation of E2F-5, a new member of the E2F family."
      Buck V. , Allen K.E. , Soerensen T. , Bybee A. , Hijmans E.M. , Voorhoeve P.M. , Bernards R. , la Thangue N.B.
      Oncogene11:31-38(1995) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    2. 2.
      "The transcriptional landscape of the mammalian genome."
      Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
      Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: NOD.
      tissue: Spleen.
    3. 3.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: FVB/N.
      tissue: Mammary tumor.
    4. 4.
      "Expression patterns of the E2F family of transcription factors during mouse nervous system development."
      Dagnino L. , Fry C.J. , Bartley S.M. , Farnham P. , Gallie B.L. , Phillips R.A.
      Mech. Dev.66:13-25(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: DEVELOPMENTAL STAGE
    5. 5.
      "Expression patterns of the E2F family of transcription factors during murine epithelial development."
      Dagnino L. , Fry C.J. , Bartley S.M. , Farnham P. , Gallie B.L. , Phillips R.A.
      Cell Growth Differ.8:553-563(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: DEVELOPMENTAL STAGE
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