E2f5 ELISA Kit for Rat(Rattus norvegicus) | EIAab.comE2f5 ELISA Kit for Rat(Rattus norvegicus)

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E2f5 (Gene name),

Transcription factor E2F5 (Protein name ), E2F5_RAT from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

E2f5;

Protein name:

Transcription factor E2F5(E2F-5);

Alternative:

Organism:

Rat (Rattus norvegicus).

General Annotation

Sub Unit:

Component of the DRTF1/E2F transcription factor complex. Binds cooperatively with DP-1 to E2F sites. Interaction with retinoblastoma protein RB1 or proteins RBL1 and RBL2 inhibits the E2F transactivation domain. Component of the DREAM complex (also named LINC complex) at least composed of E2F4, E2F5, LIN9, LIN37, LIN52, LIN54, MYBL1, MYBL2, RBL1, RBL2, RBBP4, TFDP1 and TFDP2. The complex exists in quiescent cells where it represses cell cycle-dependent genes. It dissociates in S phase when LIN9, LIN37, LIN52 and LIN54 form a subcomplex that binds to MYBL2.

Function:

Transcriptional activator that binds to E2F sites, these sites are present in the promoter of many genes whose products are involved in cell proliferation. May mediate growth factor-initiated signal transduction. May participate in differentiation processes relating to exit from G0.

Subcellular Location:

Nucleus

Protein Attributes:

Sequence length:

300

Sequence:

50:

100:

150:

200:

250:

300:

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

UniGene:

Rn.52317

STRING:

10116.ENSRNOP00000014361

Pfam:

PF02319

String:

Q62814

SMR:

Q62814

Uniprot:

Q62814

FOR

ELISA Kit for Rat E2F-5

CLIA Kit for Rat E2F-5

Polyclonal Antibody for Rat E2F-5

Monoclonal Antibody for Rat E2F-5

Protein for Rat E2F-5

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Structural characterization and specificity of expression of E2F-5: a new member of the E2F family of transcription factors."
Itoh A. , Levinson S.F. , Morita T. , Kourembanas S. , Brody J.S. , Mitsialis S.A.
Cell. Mol. Biol. Res.41:147-154(1995) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
strain: Sprague-Dawley.
tissue: Lung.

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