E2F6 ELISA Kit for Bovine(Bos taurus) | EIAab.comE2F6 ELISA Kit for Bovine(Bos taurus)

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E2F6 (Gene name),

Transcription factor E2F6 (Protein name ), E2F6_BOVIN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

E2F6;

Protein name:

Transcription factor E2F6(E2F-6);

Alternative:

Organism:

Bovine (Bos taurus).

General Annotation

Sub Unit:

Component of the DRTF1/E2F transcription factor complex. Forms heterodimers with DP family members. Part of the E2F6.com-1 complex in G0 phase composed of E2F6, MGA, MAX, TFDP1, CBX3, BAT8, EUHMTASE1, RING1, RNF2, MBLR, L3MBTL2 and YAF2. Component of some MLL1/MLL complex, at least composed of the core components MLL, ASH2L, HCFC1/HCF1, WDR5 and RBBP5, as well as the facultative components C17orf49, CHD8, E2F6, HSP70, IN80C, KIAA1267, LAS1L, MAX, MCRS1, MGA, MYST1/MOF, PELP1, PHF20, PRP31, RING2, RUVB1/TIP49A, RUVB2/TIP49B, SENP3, TAF1, TAF4, TAF6, TAF7, TAF9 and TEX10.

Function:

Inhibitor of E2F-dependent transcription. Binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3'. Has a preference for the 5'-TTTCCCGC-3' E2F recognition site. E2F-6 lacks the transcriptional activation and pocket protein binding domains. Appears to regulate a subset of E2F-dependent genes whose products are required for entry into the cell cycle but not for normal cell cycle progression. May silence expression via the recruitment of a chromatin remodeling complex containing histone H3-K9 methyltransferase activity. Overexpression delays the exit of cells from the S-phase.

Subcellular Location:

Nucleus

Protein Attributes:

Sequence length:

285

Sequence:

50:

100:

150:

200:

250:

285:

NVGTSSSKSK | PLEHPQPEKE | ENPPQQSEEV | LEVSN

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

Pfam:

PF02319

STRING:

9913.ENSBTAP00000007691

KEGG:

bta:514085

SMR:

Q08DY6

UniGene:

Bt.7678

String:

Q08DY6

Uniprot:

Q08DY6

FOR

ELISA Kit for Bovine E2F-6

CLIA Kit for Bovine E2F-6

Polyclonal Antibody for Bovine E2F-6

Monoclonal Antibody for Bovine E2F-6

Protein for Bovine E2F-6

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

NIH - Mammalian Gene Collection (MGC) project
Submitted (2006-09) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
strain: Hereford.
tissue: Fetal skin.

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