EAF2 ELISA Kit for Human(Homo sapiens) | EIAab.comEAF2 ELISA Kit for Human(Homo sapiens)

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Index > Protein center > EAF2(Gene name) > Human

EAF2 (Gene name),

ELL-associated factor 2 (Protein name ), EAF2_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

EAF2(BM-040;TRAITS);

Protein name:

ELL-associated factor 2;

Alternative:

Testosterone-regulated apoptosis inducer and tumor suppressor protein;

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Isoform 1 and isoform 2 interact with TCEA1 (By similarity). Interacts with ELL and ELL2.

Function:

Acts as a transcriptional transactivator of TCEA1 elongation activity (By similarity). Acts as a transcriptional transactivator of ELL and ELL2 elongation activities. Potent inducer of apoptosis in prostatic and non-prostatic cell lines. Inhibits prostate tumor growth in vivo.

Subcellular Location:

Nucleus speckle Colocalizes with ELL to nuclear speckles.

Protein Attributes:

Sequence length:

260

Sequence:

50:

100:

150:

200:

250:

260:

LSESGSDSDD |

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

Pfam:

PF09816

MIM:

607659

KEGG:

hsa:55840

UniGene:

Hs.477325

String:

Q96CJ1

STRING:

9606.ENSP00000273668

Uniprot:

Q96CJ1

FOR

ELISA Kit for Human ELL-associated factor 2

CLIA Kit for Human ELL-associated factor 2

Polyclonal Antibody for Human ELL-associated factor 2

Monoclonal Antibody for Human ELL-associated factor 2

Protein for Human ELL-associated factor 2

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"ELL-associated factor 2 (EAF2), a functional homolog of EAF1 with alternative ELL binding properties."
Simone F. , Luo R.T. , Polak P.E. , Kaberlein J.J. , Thirman M.J.
Blood101:2355-2362(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);FUNCTION;INTERACTION WITH ELL AND ELL2;SUBCELLULAR LOCATION;TISSUE SPECIFICITY
tissue: Bone marrow.
2.

"Suppression of prostate tumor growth by U19, a novel testosterone-regulated apoptosis inducer."
Xiao W. , Zhang Q. , Jiang F. , Pins M. , Kozlowski J.M. , Wang Z.
Cancer Res.63:4698-4704(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);FUNCTION IN APOPTOSIS;INDUCTION;SUBCELLULAR LOCATION;TISSUE SPECIFICITY
3.

"Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells."
Zhang Q.-H. , Ye M. , Wu X.-Y. , Ren S.-X. , Zhao M. , Zhao C.-J. , Fu G. , Shen Y. , Fan H.-Y. , Lu G. , Zhong M. , Xu X.-R. , Han Z.-G. , Zhang J.-W. , Tao J. , Huang Q.-H. , Zhou J. , Hu G.-X. , more...
Genome Res.10:1546-1560(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)
tissue: Bone marrow.
4.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
tissue: B-cell.
5.

"ELL-associated factors 1 and 2 are positive regulators of RNA polymerase II elongation factor ELL."
Kong S.E. , Banks C.A. , Shilatifard A. , Conaway J.W. , Conaway R.C.
Proc. Natl. Acad. Sci. U.S.A.102:10094-10098(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
6.

"A quantitative atlas of mitotic phosphorylation."
Dephoure N. , Zhou C. , Villen J. , Beausoleil S.A. , Bakalarski C.E. , Elledge S.J. , Gygi S.P.
Proc. Natl. Acad. Sci. U.S.A.105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-151 AND SER-154;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue: Cervix carcinoma.
7.

"Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."
Mayya V. , Lundgren D.H. , Hwang S.-I. , Rezaul K. , Wu L. , Eng J.K. , Rodionov V. , Han D.K.
Sci. Signal.2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-154;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue: Leukemic T-cell.
8.

"The little elongation complex regulates small nuclear RNA transcription."
Smith E.R. , Lin C. , Garrett A.S. , Thornton J. , Mohaghegh N. , Hu D. , Jackson J. , Saraf A. , Swanson S.K. , Seidel C. , Florens L. , Washburn M.P. , Eissenberg J.C. , Shilatifard A.
Mol. Cell44:954-965(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION IN THE SEC COMPLEX

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