Ecsit ELISA Kit for Mouse(Mus musculus) | EIAab.comEcsit ELISA Kit for Mouse(Mus musculus)

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Index > Protein center > Ecsit(Gene name) > Mouse

Ecsit (Gene name),

Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial (Protein name ), ECSIT_MOUSE from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Ecsit(Sitpec);

Protein name:

Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial;

Alternative:

Protein SITPEC;

Organism:

Mouse (Mus musculus).

General Annotation

Sub Unit:

Interacts with NDUFAF1 (By similarity). Interacts with MAP3K1, SMAD4 and TRAF6. Interacts with SMAD1 only after BMP4-treatment.

Function:

Required for efficient assembly of mitochondrial NADH:ubiquinone oxidoreductase (By similarity). Adapter protein of the Toll-like and IL-1 receptor signaling pathway that is involved in the activation of NF-kappa-B via MAP3K1. Promotes proteolytic activation of MAP3K1. Involved in the BMP signaling pathway. Required for normal embryonic development.

Subcellular Location:

Cytoplasm Nucleus Mitochondrion

Protein Attributes:

Sequence length:

435

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

435:

LTTSRLEGQS | PPHSPPKGPE | EDDETIQAEQ | QQGQS

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

Pfam:

PF06239

String:

Q9QZH6

UniGene:

Mm.425568

KEGG:

mmu:26940

Uniprot:

Q9QZH6

FOR

ELISA Kit for Mouse Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial

CLIA Kit for Mouse Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial

Polyclonal Antibody for Mouse Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial

Monoclonal Antibody for Mouse Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial

Protein for Mouse Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"ECSIT is an evolutionarily conserved intermediate in the Toll/IL-1 signal transduction pathway."
Kopp E. , Medzhitov R. , Carothers J. , Xiao C. , Douglas I. , Janeway C.A. , Ghosh S.
Genes Dev.13:2059-2071(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];INTERACTION WITH TRAF6 AND MAP3K1;FUNCTION;ALTERNATIVE SPLICING;TISSUE SPECIFICITY
tissue: Liver.
2.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
strain: Czech II.
strain: FVB/N.
tissue: Mammary tumor.
3.

"Ecsit is required for Bmp signaling and mesoderm formation during mouse embryogenesis."
Xiao C. , Shim J.-H. , Klueppel M. , Zhang S.S.-M. , Dong C. , Flavell R.A. , Fu X.-Y. , Wrana J.L. , Hogan B.L.M. , Ghosh S.
Genes Dev.17:2933-2949(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;SUBCELLULAR LOCATION;INTERACTION WITH SMAD1 AND SMAD4;ALTERNATIVE SPLICING;TISSUE SPECIFICITY

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