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Index > Protein center > EFCAB6(Gene name) > Human
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  • EFCAB6 (Gene name),
  • EF-hand calcium-binding domain-containing protein 6 (Protein name ),  EFCB6_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Gene name:
    EFCAB6(DJBP;KIAA1672);
    Protein name:
    EF-hand calcium-binding domain-containing protein 6;
    Alternative:
    DJ-1-binding protein(DJBP);CAP-binding protein complex-interacting protein 1;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Binds PARK7. Part of a ternary complex containing PARK7, EFCAB6/DJBP and AR.
    Function:
    Negatively regulates the androgen receptor by recruiting histone deacetylase complex, and protein DJ-1 antagonizes this inhibition by abrogation of this complex.
    Subcellular Location:
    Nucleus
    Protein Attributes:
    Sequence length:
    1501
    Sequence:
    50:
    MCKMAIIPDW | LRSHPHTRKF | THSRPHSSPC | RVYSRNGSPN | KFRSSSTTAV | 
    100:
    ANPTLSSLDV | KRILFQKITD | RGDELQKAFQ | LLDTGQNLTV | SKSELRRIIT | 
    150:
    DFLMPLTREQ | FQDVLAQIPL | STSGTVPYLA | FLSRFGGIDL | YINGIKRGGG | 
    200:
    NEMNCCRTLR | ELEIQVGEKV | FKNIKTVMKA | FELIDVNKTG | LVRPQELRRV | 
    250:
    LETFCMKLRD | EEYEKFSKHY | NIHKDTAVDY | NVFLKNLSIN | NDLNLRYCMG | 
    300:
    NQEVSLENQQ | AKNSKKERLL | GSASSEDIWR | NYSLDEIERN | FCLQLSKSYE | 
    350:
    KVEKALSAGD | PCKGGYVSFN | YLKIVLDTFV | YQIPRRIFIQ | LMKRFGLKAT | 
    400:
    TKINWKQFLT | SFHEPQGLQV | SSKGPLTKRN | SINSRNESHK | ENIITKLFRH | 
    450:
    TEDHSASLKK | ALLIINTKPD | GPITREEFRY | ILNCMAVKLS | DSEFKELMQM | 
    500:
    LDPGDTGVVN | TSMFIDLIEE | NCRMRKTSPC | TDAKTPFLLA | WDSVEEIVHD | 
    550:
    TITRNLQAFY | NMLRSYDLGD | TGRIGRNNFK | KIMHVFCPFL | TNAHFIKLCS | 
    600:
    KIQDIGSGRI | LYKKLLACIG | IDGPPTVSPV | LVPKDQLLSE | HLQKDEQQQP | 
    650:
    DLSERTKLTE | DKTTLTKKMT | TEEVIEKFKK | CIQQQDPAFK | KRFLDFSKEP | 
    700:
    NGKINVHDFK | KVLEDTGMPM | DDDQYALLTT | KIGFEKEGMS | YLDFAAGFED | 
    750:
    PPMRGPETTP | PQPPTPSKSY | VNSHFITAEE | CLKLFPRRLK | ESFRDPYSAF | 
    800:
    FKTDADRDGI | INMHDLHRLL | LHLLLNLKDD | EFERFLGLLG | LRLSVTLNFR | 
    850:
    EFQNLCEKRP | WRTDEAPQRL | IRPKQKVADS | ELACEQAHQY | LVTKAKNRWS | 
    900:
    DLSKNFLETD | NEGNGILRRR | DIKNALYGFD | IPLTPREFEK | LWARYDTEGK | 
    950:
    GHITYQEFLQ | KLGINYSPAV | HRPCAEDYFN | FMGHFTKPQQ | LQEEMKELQQ | 
    1000:
    STEKAVAARD | KLMDRHQDIS | KAFTKTDQSK | TNYISICKMQ | EVLEECGCSL | 
    1050:
    TEGELTHLLN | SWGVSRHDNA | INYLDFLRAV | ENSKSTGAQP | KEKEESMPIN | 
    1100:
    FATLNPQEAV | RKIQEVVESS | QLALSTAFSA | LDKEDTGFVK | ATEFGQVLKD | 
    1150:
    FCYKLTDNQY | HYFLRKLRIH | LTPYINWKYF | LQNFSCFLEE | TADEWAEKMP | 
    1200:
    KGPPPTSPKA | TADRDILARL | HKAVTSHYHA | ITQEFENFDT | MKTNTISREE | 
    1250:
    FRAICNRRVQ | ILTDEQFDRL | WNEMPVNAKG | RLKYPDFLSR | FSSETAATPM | 
    1300:
    ATGDSAVAQR | GSSVPDVSEG | TRSALSLPTQ | ELRPGSKSQS | HPCTPASTTV | 
    1350:
    IPGTPPLQNC | DPIESRLRKR | IQGCWRQLLK | ECKEKDVARQ | GDINASDFLA | 
    1400:
    LVEKFNLDIS | KEECQQLIIK | YDLKSNGKFA | YCDFIQSCVL | LLKAKESSLM | 
    1450:
    HRMKIQNAHK | MKEAGAETPS | FYSALLRIQP | KIVHCWRPMR | RTFKSYDEAG | 
    1500:
    TGLLSVADFR | TVLRQYSINL | SEEEFFHILE | YYDKTLSSKI | SYNDFLRAFL | 
    1501:
    Q
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    String:
    KEGG:
    Pfam:
    UniGene:
    SMR:
    Uniprot:
     
    FOR
    ELISA Kit for Human EF-hand calcium-binding domain-containing protein 6
    ELISA Kit for Human EF-hand calcium-binding domain-containing protein 6
    CLIA Kit for Human EF-hand calcium-binding domain-containing protein 6
    CLIA Kit for Human EF-hand calcium-binding domain-containing protein 6
    Polyclonal Antibody for Human EF-hand calcium-binding domain-containing protein 6
    Polyclonal Antibody for Human EF-hand calcium-binding domain-containing protein 6
    Monoclonal Antibody for Human EF-hand calcium-binding domain-containing protein 6
    Monoclonal Antibody for Human EF-hand calcium-binding domain-containing protein 6
    Protein for Human EF-hand calcium-binding domain-containing protein 6
    Protein for Human EF-hand calcium-binding domain-containing protein 6

    R&D Technical Data
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    Precision
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Recovery
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Linearity
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    References
    1. 1.
      "DJBP: a novel DJ-1-binding protein, negatively regulates the androgen receptor by recruiting histone deacetylase complex, and DJ-1 antagonizes this inhibition by abrogation of this complex."
      Niki T. , Takahashi-Niki K. , Taira T. , Iguchi-Ariga S.M.M. , Ariga H.
      Mol. Cancer Res.1:247-261(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 3);FUNCTION;SUBCELLULAR LOCATION;TISSUE SPECIFICITY;INTERACTION WITH PARK7 AND AR;VARIANT VAL-1059
      tissue: Testis.
    2. 2.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 3);VARIANTS ALA-351; TYR-400; ALA-680 AND VAL-1059
      tissue: Lung.
      tissue: Testis.
    3. 3.
      "Reevaluating human gene annotation: a second-generation analysis of chromosome 22."
      Collins J.E. , Goward M.E. , Cole C.G. , Smink L.J. , Huckle E.J. , Knowles S. , Bye J.M. , Beare D.M. , Dunham I.
      Genome Res.13:27-36(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 4)
    4. 4.
      "The DNA sequence of human chromosome 22."
      Dunham I. , Hunt A.R. , Collins J.E. , Bruskiewich R. , Beare D.M. , Clamp M. , Smink L.J. , Ainscough R. , Almeida J.P. , Babbage A.K. , Bagguley C. , Bailey J. , Barlow K.F. , Bates K.N. , Beasley O.P. , Bird C.P. , Blakey S.E. , Bridgeman A.M. , more...
      Nature402:489-495(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    5. 5.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2);VARIANT VAL-1059
      tissue: Testis.
    6. 6.
      "Identification of novel transcribed sequences on human chromosome 22 by expressed sequence tag mapping."
      Hirosawa M. , Nagase T. , Murahashi Y. , Kikuno R. , Ohara O.
      DNA Res.8:1-9(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 855-1501 (ISOFORM 5)
      tissue: Brain.
    7. 7.
      "Crystal structure of DJBP fragment which was obtained by limited proteolysis."
      Honbou K. , Suzuki N.N. , Horiuchi M. , Taira T. , Niki T. , Ariga H. , Inagaki F.
      Submitted (2005-08) to the PDB data bank
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.6 ANGSTROMS) OF 1160-1260
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