Gene name:
Efnb1 (Epl2;Eplg2;Lerk2;Stra1) ;
Protein name:
Ephrin-B1 ;
Alternative:
ELK ligand (ELK-L) ;CEK5 receptor ligand (CEK5-L) ;Stimulated by retinoic acid gene 1 protein ;EPH-related receptor tyrosine kinase ligand 2 (LERK-2) ;
Organism:
Mouse (Mus musculus).
General Annotation
Sub Unit:
Interacts with GRIP1 and GRIP2.
Function:
Cell surface transmembrane ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Binds to the receptor tyrosine kinases EPHB3 (preferred), EPHB1 and EPHA1. Binds to, and induce the collapse of, commissural axons/growth cones in vitro. May play a role in constraining the orientation of longitudinally projecting axons.
Subcellular Location:
Membrane
Single-pass type I membrane protein
Protein Attributes:
50:
MARPGQRWLS | KWLVAMVVLT | LCRLATPLAK | NLEPVSWSSL | NPKFLSGKGL |
100:
VIYPKIGDKL | DIICPRAEAG | RPYEYYKLYL | VRPEQAAACS | TVLDPNVLVT |
150:
CNKPHQEIRF | TIKFQEFSPN | YMGLEFKKYH | DYYITSTSNG | SLEGLENREG |
200:
GVCRTRTMKI | VMKVGQDPNA | VTPEQLTTSR | PSKESDNTVK | TATQAPGRGS |
250:
QGDSDGKHET | VNQEEKSGPG | AGGGGSGDSD | SFFNSKVALF | AAVGAGCVIF |
300:
LLIIIFLTVL | LLKLRKRHRK | HTQQRAAALS | LSTLASPKGG | SGTAGTEPSD |
345:
IIIPLRTTEN | NYCPHYEKVS | GDYGHPVYIV | QEMPPQSPAN | IYYKV
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Mouse
Rat
Human
Chicken
ELISA Kit for Mouse Ephrin-B1
ELISA Kit for Mouse Ephrin-B1
ELISA Kit for Mouse Ephrin-B1
ELISA Kit for Mouse Ephrin-B1
CLIA Kit for Mouse Ephrin-B1
CLIA Kit for Mouse Ephrin-B1
CLIA Kit for Mouse Ephrin-B1
CLIA Kit for Mouse Ephrin-B1
Polyclonal Antibody for Mouse Ephrin-B1
Polyclonal Antibody for Mouse Ephrin-B1
Polyclonal Antibody for Mouse Ephrin-B1
Polyclonal Antibody for Mouse Ephrin-B1
Monoclonal Antibody for Mouse Ephrin-B1
Monoclonal Antibody for Mouse Ephrin-B1
Monoclonal Antibody for Mouse Ephrin-B1
Monoclonal Antibody for Mouse Ephrin-B1
Protein for Mouse Ephrin-B1
Protein for Mouse Ephrin-B1
Protein for Mouse Ephrin-B1
Protein for Mouse Ephrin-B1
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [GENOMIC DNA]
strain :
129/Sv .
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
tissue :
Brain .
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
strain :
FVB/N .
tissue :
Mammary gland .
5.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION
6.
"Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations."
Munton R.P.
,
Tweedie-Cullen R.
,
Livingstone-Zatchej M.
,
Weinandy F.
,
Waidelich M.
,
Longo D.
,
Gehrig P.
,
Potthast F.
,
Rutishauser D.
,
Gerrits B.
,
Panse C.
,
Schlapbach R.
,
Mansuy I.M.
Mol. Cell. Proteomics6:283-293(2007)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue :
Brain cortex .