Efnb1 ELISA Kit for Rat(Rattus norvegicus) | EIAab.comEfnb1 ELISA Kit for Rat(Rattus norvegicus)

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Efnb1 (Gene name),

Ephrin-B1 (Protein name ), EFNB1_RAT from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Efnb1(Eplg2;Lerk2);

Protein name:

Ephrin-B1;

Alternative:

EPH-related receptor tyrosine kinase ligand 2(LERK-2);ELK ligand(ELK-L);

Organism:

Rat (Rattus norvegicus).

General Annotation

Sub Unit:

Binds to the receptor tyrosine kinases EPHB3 (preferred), EPHB1 and EPHB2. Interacts with GRIP1 and GRIP2.

Function:

Cell surface transmembrane ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Binds to the receptor tyrosine kinases EPHB3 (preferred), EPHB1 and EPHA1. Binds to, and induce the collapse of, commissural axons/growth cones in vitro. May play a role in constraining the orientation of longitudinally projecting axons.

Subcellular Location:

Membrane Single-pass type I membrane protein

Protein Attributes:

Sequence length:

345

Sequence:

50:

100:

150:

200:

250:

300:

345:

IIIPLRTTEN | NYCPHYEKVS | GDYGHPVYIV | QEMPPQSPAN | IYYKV

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

String:

P52796

Pfam:

PF00812

STRING:

10116.ENSRNOP00000009635

SMR:

P52796

UniGene:

Rn.44398

Uniprot:

P52796

FOR

ELISA Kit for Rat Ephrin-B1

CLIA Kit for Rat Ephrin-B1

Polyclonal Antibody for Rat Ephrin-B1

Monoclonal Antibody for Rat Ephrin-B1

Protein for Rat Ephrin-B1

R&D Technical Data

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Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

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Linearity

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References

1.

"LERK-2, a binding protein for the receptor-tyrosine kinase ELK, is evolutionarily conserved and expressed in a developmentally regulated pattern."
Fletcher F.A. , Carpenter M. , Shilling H. , Baum P. , Ziegler S. , Gimpel S. , Hollingsworth T. , Vanden Bos T. , Davison B.L. , Lyman S.D. , Beckmann M.P.
Oncogene9:3241-3248(1994) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
tissue: Brain.
2.

"EphrinB ligands recruit GRIP family PDZ adaptor proteins into raft membrane microdomains."
Brueckner K. , Pablo Labrador J. , Scheiffele P. , Herb A. , Seeburg P.H. , Klein R.
Neuron22:511-524(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH GRIP1 AND GRIP2
tissue: Fetal brain.

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