Protein name:
Embryonal Fyn-associated substrate (hEFS) ;
Alternative:
Cas scaffolding protein family member 3 ;
Organism:
Human (Homo sapiens).
General Annotation
Function:
Docking protein which plays a central coordinating role for tyrosine-kinase-based signaling related to cell adhesion. May serve as an activator of SRC and a downstream effector. Interacts with the SH3 domain of FYN and with CRK, SRC, and YES.
Subcellular Location:
N/A
Protein Attributes:
50:
MAIATSTQLA | RALYDNTAES | PQELSFRRGD | VLRVLQREGA | GGLDGWCLCS |
100:
LHGQQGIVPA | NRVKLLPAGP | APKPSLSPAS | PAQPGSPYPA | PDHSNEDQEV |
150:
YVVPPPARPC | PTSGPPAGPC | PPSPDLIYKI | PRASGTQLAA | PRDALEVYDV |
200:
PPTALRVPSS | GPYDCPASFS | HPLTRVAPQP | PGEDDAPYDV | PLTPKPPAEL |
250:
EPDLEWEGGR | EPGPPIYAAP | SNLKRASALL | NLYEAPEELL | ADGEGGGTDE |
300:
GIYDVPLLGP | EAPPSPEPPG | ALASHDQDTL | AQLLARSPPP | PHRPRLPSAE |
350:
SLSRRPLPAL | PVPEAPSPSP | VPSPAPGRKG | SIQDRPLPPP | PPRLPGYGGP |
400:
KVEGDPEGRE | MEDDPAGHHN | EYEGIPMAEE | YDYVHLKGMD | KAQGSRPPDQ |
450:
ACTGDPELPE | RGMPAPQEAL | SPGEPLVVST | GDLQLLYFYA | GQCQSHYSAL |
500:
QAAVAALMSS | TQANQPPRLF | VPHSKRVVVA | AHRLVFVGDT | LGRLAASAPL |
550:
RAQVRAAGTA | LGQALRATVL | AVKGAALGYP | SSPAIQEMVQ | CVTELAGQAL |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Mouse
Polyclonal Antibody for Human hEFS
Polyclonal Antibody for Human hEFS
Monoclonal Antibody for Human hEFS
Monoclonal Antibody for Human hEFS
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
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Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS EFS1 AND EFS2)
tissue :
Hippocampus .
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Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS EFS1 AND 3)
tissue :
Amygdala .
tissue :
Substantia nigra .
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
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Submitted (2005-09) to the EMBL/GenBank/DDBJ databases
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
5.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM EFS2)
tissue :
Brain .
6.
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Science314:268-274(2006)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : VARIANT [LARGE SCALE ANALYSIS] ILE-361