Gene name:
Egr2 (Egr-2;Krox-20;Zfp-25) ;
Protein name:
Early growth response protein 2 (EGR-2) ;
Alternative:
Zinc finger protein Krox-20 ;Zinc finger protein Krox-20 (EGR-2) ;
Organism:
Mouse (Mus musculus).
General Annotation
Sub Unit:
Interacts with HCFC1 (By similarity). Interacts with WWP2. Interacts with CITED1. Interacts (via phosphorylated form) with SFN.
Function:
Sequence-specific DNA-binding transcription factor. Binds to two specific DNA sites located in the promoter region of HOXA4. Binds to the promoter region of ERBB2. May play a role in the regulation of hindbrain segmentation, might act in combination with the Hox network to specify odd and even rhombomeres, and might participate in the control of the expression of some of the homeobox containing genes.
Subcellular Location:
Nucleus
Protein Attributes:
50:
MMTAKAVDKI | PVTLSGFMHQ | LPDSLYPVED | LAASSVTIFP | NGELGGPFDQ |
100:
MNGVAGDGMI | NIDMTGEKRP | LDLPYPSSFA | PISAPRNQTF | TYMGKFSIDP |
150:
QYPGASCYPE | GIINIVSAGI | LQGVTPPAST | TASSSVTSAS | PNPLATGPLG |
200:
VCTMSQTQPE | LDHLYSPPPP | PPPYSGCTGD | LYQDPSAFLS | PPSTTSTSSL |
250:
AYQPPPSYPS | PKPAMDPGLI | PMIPDYPGFF | PSPCQRDPHG | AAGPDRKPFP |
300:
CPLDSLRVPP | PLTPLSTIRN | FTLGGPGAGV | TGPGASGGGE | GPRLPGSGSA |
350:
AVTATPYNPH | HLPLRPILRP | RKYPNRPSKT | PVHERPYPCP | AEGCDRRFSR |
400:
SDELTRHIRI | HTGHKPFQCR | ICMRNFSRSD | HLTTHIRTHT | GEKPFACDYC |
450:
GRKFARSDER | KRHTKIHLRQ | KERKSSAPSA | PPSAQSSASG | PGGSQAGGSL |
470:
CGNSAIGGPL | ASCTSRTRTP |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Rat
Pig
Mouse
Human
ELISA Kit for Mouse EGR-2
ELISA Kit for Mouse EGR-2
ELISA Kit for Mouse EGR-2
ELISA Kit for Mouse EGR-2
Polyclonal Antibody for Mouse EGR-2
Polyclonal Antibody for Mouse EGR-2
Polyclonal Antibody for Mouse EGR-2
Polyclonal Antibody for Mouse EGR-2
Monoclonal Antibody for Mouse EGR-2
Monoclonal Antibody for Mouse EGR-2
Monoclonal Antibody for Mouse EGR-2
Monoclonal Antibody for Mouse EGR-2
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [GENOMIC DNA] (ISOFORMS LONG AND SHORT)
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM SHORT)
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM LONG)
strain :
FVB/N .
tissue :
Mammary gland .
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 339-417
5.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION
6.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION
7.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : DOMAINS
8.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION;INTERACTION WITH CITED1 AND SFN;MUTAGENESIS OF SER-377;DNA-BINDING;SUBCELLULAR LOCATION;TISSUE SPECIFICITY
9.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : UBIQUITINATION;INTERACTION WITH WWP2;MUTAGENESIS OF TYR-174 AND TYR-208