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Index > Protein center > Ei24(Gene name) > Mouse
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  • Ei24 (Gene name),
  • Etoposide-induced protein 2.4 (Protein name ),  EI24_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Related Databases
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  • Gene name:
    Ei24(Pig8);
    Protein name:
    Etoposide-induced protein 2.4;
    Alternative:
    p53-induced gene 8 protein;
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Interacts with BCL2.
    Function:
    Acts as a negative growth regulator via p53-mediated apoptosis pathway. Regulates formation of degradative autolysosomes during autophagy.
    Subcellular Location:
    Nucleus membrane Multi-pass membrane protein Cytoplasm Endoplasmic reticulum membrane Multi-pass membrane protein
    Protein Attributes:
    Sequence length:
    340
    Sequence:
    50:
    MADSVKTFLQ | DLGRGIKDSI | WGICTISKLD | ARIQQKREEQ | RRRRASSLLA | 
    100:
    QRRPQSVERK | QESEPRIVSR | IFQCCAWNGG | VFWFSLLLFY | RVFIPVLQSV | 
    150:
    TARIIGDPSL | HGDVWSWLEF | FLTSIFSALW | VLPLFVLSKV | VNAIWFQDIA | 
    200:
    DLAFEVSGRK | PHPFPSVSKI | IADMLFNLLL | QALFLIQGMF | VSLFPIHLVG | 
    250:
    QLVSLLHMSL | LYSLYCFEYR | WFNKGIEMHQ | RLSNIERNWP | YYFGFGLPLA | 
    300:
    FLTAMQSSYI | ISGCLFSILF | PLFIISANEA | KTPGKAYLFQ | LRLFSLVVFL | 
    340:
    SNRLFHKTVY | LQSALSSSSS | AEKFPSPHPS | PAKLKAAAGH | 
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    String:
    UniGene:
    KEGG:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse Etoposide-induced protein 2.4
    ELISA Kit for Mouse Etoposide-induced protein 2.4
    ELISA Kit for Mouse Etoposide-induced protein 2.4
    ELISA Kit for Mouse Etoposide-induced protein 2.4
    CLIA Kit for Mouse Etoposide-induced protein 2.4
    CLIA Kit for Mouse Etoposide-induced protein 2.4
    CLIA Kit for Mouse Etoposide-induced protein 2.4
    CLIA Kit for Mouse Etoposide-induced protein 2.4
    Polyclonal Antibody for Mouse Etoposide-induced protein 2.4
    Polyclonal Antibody for Mouse Etoposide-induced protein 2.4
    Polyclonal Antibody for Mouse Etoposide-induced protein 2.4
    Polyclonal Antibody for Mouse Etoposide-induced protein 2.4
    Monoclonal Antibody for Mouse Etoposide-induced protein 2.4
    Monoclonal Antibody for Mouse Etoposide-induced protein 2.4
    Monoclonal Antibody for Mouse Etoposide-induced protein 2.4
    Monoclonal Antibody for Mouse Etoposide-induced protein 2.4
    Protein for Mouse Etoposide-induced protein 2.4
    Protein for Mouse Etoposide-induced protein 2.4
    Protein for Mouse Etoposide-induced protein 2.4
    Protein for Mouse Etoposide-induced protein 2.4

    R&D Technical Data
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    Precision
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    Linearity
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    References
    1. 1.
      "Identification and cloning of EI24, a gene induced by p53 in etoposide-treated cells."
      Lehar S.M. , Nacht M. , Jacks T. , Vater C.A. , Chittenden T. , Guild B.C.
      Oncogene12:1181-1187(1996) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];INDUCTION
      tissue: Fibroblast.
    2. 2.
      "ei24, a p53 response gene involved in growth suppression and apoptosis."
      Gu Z. , Flemington C. , Chittenden T. , Zambetti G.P.
      Mol. Cell. Biol.20:233-241(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];FUNCTION;INDUCTION
    3. 3.
      "The transcriptional landscape of the mammalian genome."
      Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
      Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: C57BL/6J.
      strain: NOD.
      tissue: Spleen.
    4. 4.
      "Apoptosis factor EI24/PIG8 is a novel endoplasmic reticulum-localized Bcl-2-binding protein which is associated with suppression of breast cancer invasiveness."
      Zhao X. , Ayer R.E. , Davis S.L. , Ames S.J. , Florence B. , Torchinsky C. , Liou J.S. , Shen L. , Spanjaard R.A.
      Cancer Res.65:2125-2129(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INTERACTION WITH BCL2;SUBCELLULAR LOCATION
    5. 5.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-326;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Liver.
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