Protein name:
EP300-interacting inhibitor of differentiation 2 (EID-2) ;
Alternative:
EID-1-like inhibitor of differentiation 2 ;CREBBP/EP300 inhibitor 2 ;
Organism:
Bovine (Bos taurus).
General Annotation
Sub Unit:
Heterodimer with EID2B. Interacts with the C-terminus of EP300. Interacts with HDAC1 and HDAC2. Interacts with SMAD2, SMAD4 and with the MH2 domain of SMAD3.
Function:
Interacts with EP300 and acts as a repressor of MYOD-dependent transcription and muscle differentiation. Inhibits EP300 histone acetyltransferase activity. Acts as a repressor of TGFB/SMAD transcriptional responses. May act as a repressor of the TGFB/SMAD3-dependent signaling by selectively blocking formation of TGFB-induced SMAD3-SMAD4 complex.
Subcellular Location:
Nucleus
Protein Attributes:
50:
MSELPADQGV | PPAGAANDNG | DVRQAEVGGR | RREPAPAQPV | AARDRPMAAA |
100:
VEGSMASPVE | GPVPEAREGP | MAASREGLGA | AAREARMAEV | ARLLAEPAEE |
150:
EGPEGRPRSR | PGNGPGLAAL | PYLRLRHPLG | VLGINYQQFL | RHYLEHYPIA |
200:
PGRIQELEGR | RRRFVEACRA | REAAFDAEYQ | RNPQRMDFDI | LTFSITLTAS |
219:
EIINPLIEEL | GCDKFISRE
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Bovine
Mouse
ELISA Kit for Bovine EID-2
ELISA Kit for Bovine EID-2
ELISA Kit for Bovine EID-2
CLIA Kit for Bovine EID-2
CLIA Kit for Bovine EID-2
CLIA Kit for Bovine EID-2
Polyclonal Antibody for Bovine EID-2
Polyclonal Antibody for Bovine EID-2
Polyclonal Antibody for Bovine EID-2
Monoclonal Antibody for Bovine EID-2
Monoclonal Antibody for Bovine EID-2
Monoclonal Antibody for Bovine EID-2
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
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Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
strain :
Hereford .
tissue :
Ascending colon .