Gene name:
Apela (Ela;Ende;Gm10664;Tdl) ;
Protein name:
Apelin receptor early endogenous ligand ;
Alternative:
Protein Toddler ;Protein Elabela ;
Organism:
Mouse (Mus musculus).
General Annotation
Sub Unit:
Interacts with APLNR.
Function:
Hormone required during early development for endoderm differentiation and heart morphogenesis by acting as a ligand for the apelin receptor (APLNR). Acts as a motogen by promoting endoderm and mesendoderm cell migration during gastrulation by binding and activating the apelin receptor, thereby driving internalization of the apelin receptor. Plays a key role during heart development by acting as a ligand for the apelin receptor.
Subcellular Location:
Secreted
Extracellular space
Secreted
Protein Attributes:
50:
MRFQPLFWVF | FIFAMSLLFI | SEQKPVNFPR | RRKLYRHNCF | RRRCIPLHSR |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Mouse
Human
ELISA Kit for Mouse Apelin receptor early endogenous ligand
ELISA Kit for Mouse Apelin receptor early endogenous ligand
CLIA Kit for Mouse Apelin receptor early endogenous ligand
CLIA Kit for Mouse Apelin receptor early endogenous ligand
Polyclonal Antibody for Mouse Apelin receptor early endogenous ligand
Polyclonal Antibody for Mouse Apelin receptor early endogenous ligand
Monoclonal Antibody for Mouse Apelin receptor early endogenous ligand
Monoclonal Antibody for Mouse Apelin receptor early endogenous ligand
Protein for Mouse Apelin receptor early endogenous ligand
Protein for Mouse Apelin receptor early endogenous ligand
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
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Science309:1559-1563(2005)
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Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
strain :
C57BL/6J .
tissue :
Embryo .
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Submitted (1999-03) to the EMBL/GenBank/DDBJ databases
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
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PLoS Biol.7:E1000112-E1000112(2009)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
strain :
C57BL/6J .
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : TISSUE SPECIFICITY;DEVELOPMENTAL STAGE