Protein name:
Actin, cytoplasmic 1 ;
Alternative:
Beta-actin ;
Organism:
Mouse (Mus musculus).
General Annotation
Sub Unit:
Polymerization of globular actin (G-actin) leads to a structural filament (F-actin) in the form of a two-stranded helix. Each actin can bind to 4 others. Identified in a mRNP granule complex, at least composed of ACTB, ACTN4, DHX9, ERG, HNRNPA1, HNRNPA2B1, HNRNPAB, HNRNPD, HNRNPL, HNRNPR, HNRNPU, HSPA1, HSPA8, IGF2BP1, ILF2, ILF3, NCBP1, NCL, PABPC1, PABPC4, PABPN1, RPLP0, RPS3, RPS3A, RPS4X, RPS8, RPS9, SYNCRIP, TROVE2, YBX1 and untranslated mRNAs. Component of the BAF complex, which includes at least actin (ACTB), ARID1A, ARID1B/BAF250, SMARCA2, SMARCA4/BRG1, MARCB1/BAF47, ACTL6A/BAF53, ACTL6B/BAF53B, SMARCE1/BAF57, SMARCC1/BAF155, SMARCC2/BAF170, SMARCB1/SNF5/INI1, and one or more of SMARCD1/BAF60A, SMARCD2/BAF60B, or SMARCD3/BAF60C. In muscle cells, the BAF complex also contains DPF3. Found in a complex with XPO6, Ran, ACTB and PFN1. Component of a complex composed at least of ACTB, AP2M1, AP2A1, AP2A2, MEGF10 and VIM. Component of the MLL5-L complex, at least composed of MLL5, STK38, PPP1CA, PPP1CB, PPP1CC, HCFC1, ACTB and OGT. Interacts with XPO6 and EMD. Interacts with ERBB2.
Function:
Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.
Subcellular Location:
Cytoplasm
cytoskeleton
Localized in cytoplasmic mRNP granules containing untranslated mRNAs.
Protein Attributes:
50:
MDDDIAALVV | DNGSGMCKAG | FAGDDAPRAV | FPSIVGRPRH | QGVMVGMGQK |
100:
DSYVGDEAQS | KRGILTLKYP | IEHGIVTNWD | DMEKIWHHTF | YNELRVAPEE |
150:
HPVLLTEAPL | NPKANREKMT | QIMFETFNTP | AMYVAIQAVL | SLYASGRTTG |
200:
IVMDSGDGVT | HTVPIYEGYA | LPHAILRLDL | AGRDLTDYLM | KILTERGYSF |
250:
TTTAEREIVR | DIKEKLCYVA | LDFEQEMATA | ASSSSLEKSY | ELPDGQVITI |
300:
GNERFRCPEA | LFQPSFLGME | SCGIHETTFN | SIMKCDVDIR | KDLYANTVLS |
350:
GGTTMYPGIA | DRMQKEITAL | APSTMKIKII | APPERKYSVW | IGGSILASLS |
375:
TFQQMWISKQ | EYDESGPSIV | HRKCF
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Dog
Chicken
Mouse
Rat
Bovine
Rabbit
Pig
ELISA Kit for Mouse Actin, cytoplasmic 1
ELISA Kit for Mouse Actin, cytoplasmic 1
ELISA Kit for Mouse Actin, cytoplasmic 1
ELISA Kit for Mouse Actin, cytoplasmic 1
ELISA Kit for Mouse Actin, cytoplasmic 1
ELISA Kit for Mouse Actin, cytoplasmic 1
ELISA Kit for Mouse Actin, cytoplasmic 1
ELISA Kit for Mouse Actin, cytoplasmic 1
CLIA Kit for Mouse Actin, cytoplasmic 1
CLIA Kit for Mouse Actin, cytoplasmic 1
CLIA Kit for Mouse Actin, cytoplasmic 1
CLIA Kit for Mouse Actin, cytoplasmic 1
CLIA Kit for Mouse Actin, cytoplasmic 1
CLIA Kit for Mouse Actin, cytoplasmic 1
CLIA Kit for Mouse Actin, cytoplasmic 1
CLIA Kit for Mouse Actin, cytoplasmic 1
Polyclonal Antibody for Mouse Actin, cytoplasmic 1
Polyclonal Antibody for Mouse Actin, cytoplasmic 1
Polyclonal Antibody for Mouse Actin, cytoplasmic 1
Polyclonal Antibody for Mouse Actin, cytoplasmic 1
Polyclonal Antibody for Mouse Actin, cytoplasmic 1
Polyclonal Antibody for Mouse Actin, cytoplasmic 1
Polyclonal Antibody for Mouse Actin, cytoplasmic 1
Polyclonal Antibody for Mouse Actin, cytoplasmic 1
Monoclonal Antibody for Mouse Actin, cytoplasmic 1
Monoclonal Antibody for Mouse Actin, cytoplasmic 1
Monoclonal Antibody for Mouse Actin, cytoplasmic 1
Monoclonal Antibody for Mouse Actin, cytoplasmic 1
Monoclonal Antibody for Mouse Actin, cytoplasmic 1
Monoclonal Antibody for Mouse Actin, cytoplasmic 1
Monoclonal Antibody for Mouse Actin, cytoplasmic 1
Monoclonal Antibody for Mouse Actin, cytoplasmic 1
Protein for Mouse Actin, cytoplasmic 1
Protein for Mouse Actin, cytoplasmic 1
Protein for Mouse Actin, cytoplasmic 1
Protein for Mouse Actin, cytoplasmic 1
Protein for Mouse Actin, cytoplasmic 1
Protein for Mouse Actin, cytoplasmic 1
Protein for Mouse Actin, cytoplasmic 1
Protein for Mouse Actin, cytoplasmic 1
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
2.
"The transcriptional landscape of the mammalian genome."
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more...
Science309:1559-1563(2005)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
strain :
BALB/c .
strain :
C57BL/6J .
strain :
NOD .
tissue :
Bone marrow .
tissue :
Mammary gland .
tissue :
Thymus .
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PROTEIN SEQUENCE OF 2-375;CLEAVAGE OF INITIATOR METHIONINE;ACETYLATION AT ASP-2;METHYLATION AT HIS-73
tissue :
Thymus .
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PROTEIN SEQUENCE OF 19-39; 51-61; 85-113; 148-177; 184-191; 197-206; 216-254; 257-284; 291-326 AND 360-372;IDENTIFICATION BY MASS SPECTROMETRY
strain :
C57BL/6 .
strain :
OF1 .
tissue :
Brain .
tissue :
Hippocampus .
5.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] OF 27-375
6.
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Cited for : ACETYLATION
tissue :
Muscle .
7.
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Cited for : ISGYLATION
8.
"MsrB1 and MICALs regulate actin assembly and macrophage function via reversible stereoselective methionine oxidation."
Lee B.C.
,
Peterfi Z.
,
Hoffmann F.W.
,
Moore R.E.
,
Kaya A.
,
Avanesov A.
,
Tarrago L.
,
Zhou Y.
,
Weerapana E.
,
Fomenko D.E.
,
Hoffmann P.R.
,
Gladyshev V.N.
Mol. Cell51:397-404(2013)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
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Cited for : OXIDATION AT MET-44 AND MET-47;DEOXIDATION AT MET-44 AND MET-47