Akap1 ELISA Kit for Mouse(Mus musculus) | EIAab.comAkap1 ELISA Kit for Mouse(Mus musculus)

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Akap1 (Gene name),

A-kinase anchor protein 1, mitochondrial (Protein name ), AKAP1_MOUSE from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Akap1(Akap);

Protein name:

A-kinase anchor protein 1, mitochondrial;

Alternative:

Protein kinase A-anchoring protein 1(PRKA1);Dual specificity A-kinase-anchoring protein 1(D-AKAP-1);Spermatid A-kinase anchor protein(S-AKAP);

Organism:

Mouse (Mus musculus).

General Annotation

Sub Unit:

N/A

Function:

Differentially targeted protein that binds to type I and II regulatory subunits of protein kinase A. Anchors them to the cytoplasmic face of the mitochondrial outer membrane or allows them to reside in the endoplasmic reticulum. Does not contain the classic KDEL endoplasmic reticulum-targeting sequence. This explains how it is able to switch its localization, either being in the endoplasmic reticulum or in the mitochondria depending on which N-terminal part begins the isoform. The longest N-terminal part only present in isoform 2 and isoform 4 acts as a suppressor of mitochondrial targeting and as an activator of recessive endoplasmic reticulum targeting motif.

Subcellular Location:

Isoform 6 Mitochondrion outer membrane

Protein Attributes:

Sequence length:

857

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

500:

550:

600:

650:

700:

750:

800:

850:

857:

DSYYASL

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

UniGene:

Mm.2969

Pfam:

PF00013

String:

O08715

SMR:

O08715

KEGG:

mmu:11640

Uniprot:

O08715

FOR

ELISA Kit for Mouse A-kinase anchor protein 1, mitochondrial

Cat.:

E15276m

Price:

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MSDS:

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Packing:

96T

ELISA Kit for Mouse A-kinase anchor protein 1, mitochondrial

Cat.:

E15276h

Price:

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MSDS:

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Packing:

96T

ELISA Kit for Mouse A-kinase anchor protein 1, mitochondrial

Cat.:

E15276r

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MSDS:

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Packing:

96T

CLIA Kit for Mouse A-kinase anchor protein 1, mitochondrial

Cat.:

U15276r

Price:

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MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Mouse A-kinase anchor protein 1, mitochondrial

Cat.:

U15276m

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Mouse A-kinase anchor protein 1, mitochondrial

Cat.:

U15276h

Price:

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MSDS:

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Packing:

96T

Polyclonal Antibody for Mouse A-kinase anchor protein 1, mitochondrial

Cat.:

P15276Rb-h

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Packing:

40ug/0.2ml

Polyclonal Antibody for Mouse A-kinase anchor protein 1, mitochondrial

Cat.:

P15276Rb-r

Price:

Please sign in first.

Packing:

40ug/0.2ml

Polyclonal Antibody for Mouse A-kinase anchor protein 1, mitochondrial

Cat.:

P15276Rb-m

Price:

Please sign in first.

Packing:

40ug/0.2ml

Monoclonal Antibody for Mouse A-kinase anchor protein 1, mitochondrial

Protein for Mouse A-kinase anchor protein 1, mitochondrial

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Identification of a novel protein kinase A anchoring protein that binds both type I and type II regulatory subunits."
Huang L.J.-S. , Durick K. , Weiner J.A. , Chun J. , Taylor S.S.
J. Biol. Chem.272:8057-8064(1997) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1; 2; 3 AND 4)
tissue: Embryo.
2.

Huang L.J.-S. , Durick K. , Taylor S.S.
Submitted (1998-07) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SEQUENCE REVISION
3.

"Organelle-specific targeting of protein kinase AII (PKAII). Molecular and in situ characterization of murine A kinase anchor proteins that recruit regulatory subunits of PKAII to the cytoplasmic surface of mitochondria."
Chen Q. , Lin R.-Y. , Rubin C.S.
J. Biol. Chem.272:15247-15257(1997) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 3; 5 AND 6)
strain: BALB/c.
tissue: Testis.
4.

"Lineage-specific biology revealed by a finished genome assembly of the mouse."
Church D.M. , Goodstadt L. , Hillier L.W. , Zody M.C. , Goldstein S. , She X. , Bult C.J. , Agarwala R. , Cherry J.L. , DiCuccio M. , Hlavina W. , Kapustin Y. , Meric P. , Maglott D. , Birtle Z. , Marques A.C. , Graves T. , Zhou S. , more...
PLoS Biol.7:E1000112-E1000112(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
strain: C57BL/6J.
5.

"NH2-Terminal targeting motifs direct dual specificity A-kinase-anchoring protein 1 (D-AKAP1) to either mitochondria or endoplasmic reticulum."
Huang L.J.-S. , Wang L. , Ma Y. , Durick K. , Perkins G. , Deerinck T.J. , Ellisman M.H. , Taylor S.S.
J. Cell Biol.145:951-959(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION
6.

"Large-scale phosphorylation analysis of mouse liver."
Villen J. , Beausoleil S.A. , Gerber S.A. , Gygi S.P.
Proc. Natl. Acad. Sci. U.S.A.104:1488-1493(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-55; SER-101 AND SER-103;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue: Liver.
7.

"Specific phosphopeptide enrichment with immobilized titanium ion affinity chromatography adsorbent for phosphoproteome analysis."
Zhou H. , Ye M. , Dong J. , Han G. , Jiang X. , Wu R. , Zou H.
J. Proteome Res.7:3957-3967(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-55;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue: Liver.

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