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Index > Protein center > ANGPTL4(Gene name) > Bovine
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  • ANGPTL4 (Gene name),
  • Angiopoietin-related protein 4 (Protein name ),  ANGL4_BOVIN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    ANGPTL4;
    Protein name:
    Angiopoietin-related protein 4;
    Alternative:
    Angiopoietin-like protein 4;
    Organism:
    Bovine (Bos taurus). 
    General Annotation
    Sub Unit:
    Homooligomer. The homooligomer undergoes proteolytic processing to release its carboxyl fibrinogen-like domain, which circulates as a monomer. The homooligomer unprocessed form is able to interact with the extracellular matrix.
    Function:
    Protein with hypoxia-induced expression in endothelial cells. May act as a regulator of angiogenesis and modulate tumorgenesis. Inhibits proliferation, migration, and tubule formation of endothelial cells and reduces vascular leakage. May exert a protective function on endothelial cells through an endocrine action. It is directly involved in regulating glucose homeostasis, lipid metabolism, and insulin sensitivity. In response to hypoxia, the unprocessed form of the protein accumulates in the subendothelial extracellular matrix (ECM). The matrix-associated and immobilized unprocessed form limits the formation of actin stress fibers and focal contacts in the adhering endothelial cells and inhibits their adhesion. It also decreases motility of endothelial cells and inhibits the sprouting and tube formation.
    Subcellular Location:
    Secreted Secreted extracellular space extracellular matrix The unprocessed form interacts with the extracellular matrix. This may constitute a dynamic reservoir, a regulatory mechanism of the bioavailability of ANGPTL4.
    Protein Attributes:
    Sequence length:
    410
    Sequence:
    50:
    MRCAPTAGAA | LMLCAATAGL | LSAQGRPEPP | ETPRFASWDE | VNVLAHGLLQ | 
    100:
    LGHGLREHVE | RTRGQLGELE | RRLGACGAAC | KDPEGSAAPP | RAQANLVNPG | 
    150:
    GGDASPETLR | SLKTQLEAQN | SRIQQLFQKV | AQQQRHLEKQ | QLRIQNLQSQ | 
    200:
    MDHLAPRHLG | HEMAKPARRK | RLPKMAQLAG | PAHNISRLHR | LPRDCQELFE | 
    250:
    EGERESGLFQ | IQPQGSPPFL | VNCKMTSDGG | WTVIQRRQDG | SVDFNQPWEA | 
    300:
    YKDGFGDPQG | EFWLGLEKVH | HILGDRGSRL | AVQLQDWEGN | AESLQFPIHL | 
    350:
    GGEDTAYSLQ | LTPPVASKLG | ATTFSPSGLS | LPFSTWDQDH | DLRGDKNCAR | 
    400:
    SLSGGWWFGT | CSHSNLNGQY | FHSIPRQRQQ | RKKGIFWKTW | RGRYYPLQAT | 
    410:
    TILVQPTAAS | 
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    UniGene:
    Pfam:
    String:
    Uniprot:
     
    FOR
    ELISA Kit for Bovine Angiopoietin-related protein 4
    Cat.:
    E2085h
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    MSDS:
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    Packing:
    96T
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    ELISA Kit for Bovine Angiopoietin-related protein 4
    Cat.:
    E2085m
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    MSDS:
    Please sign in first.
    Packing:
    96T
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    ELISA Kit for Bovine Angiopoietin-related protein 4
    Cat.:
    E2085b
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    MSDS:
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    Packing:
    96T
    ELISA Kit for Bovine Angiopoietin-related protein 4
    Cat.:
    E2085r
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    MSDS:
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    Packing:
    96T
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    ELISA Kit for Bovine Angiopoietin-related protein 4
    Cat.:
    E2085p
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Bovine Angiopoietin-related protein 4
    Cat.:
    U2085p
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Bovine Angiopoietin-related protein 4
    Cat.:
    U2085b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Bovine Angiopoietin-related protein 4
    Cat.:
    U2085m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Bovine Angiopoietin-related protein 4
    Cat.:
    U2085h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Bovine Angiopoietin-related protein 4
    Cat.:
    U2085r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Bovine Angiopoietin-related protein 4
    Cat.:
    P2085Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Bovine Angiopoietin-related protein 4
    Cat.:
    P2085Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Bovine Angiopoietin-related protein 4
    Polyclonal Antibody for Bovine Angiopoietin-related protein 4
    Cat.:
    P2085Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Bovine Angiopoietin-related protein 4
    Monoclonal Antibody for Bovine Angiopoietin-related protein 4
    Monoclonal Antibody for Bovine Angiopoietin-related protein 4
    Monoclonal Antibody for Bovine Angiopoietin-related protein 4
    Monoclonal Antibody for Bovine Angiopoietin-related protein 4
    Monoclonal Antibody for Bovine Angiopoietin-related protein 4
    Protein for Bovine Angiopoietin-related protein 4
    Protein for Bovine Angiopoietin-related protein 4
    Protein for Bovine Angiopoietin-related protein 4
    Cat.:
    R2085h
    Price:
    Please sign in first.
    Packing:
    1mg
    Purity:
    >90%
    Protein for Bovine Angiopoietin-related protein 4
    Protein for Bovine Angiopoietin-related protein 4

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    Precision
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    Linearity
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    References
    1. 1.
      Ma Y. , Xu S.-Z. , Zhang Y.-H. , Gao X. , Ren H.-Y. , Xin Y.-P. , Gao S.-X.
      Submitted (2005-12) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    2. 2.
      NIH - Mammalian Gene Collection (MGC) project
      Submitted (2005-09) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: Hereford.
      tissue: Uterus.
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