Protein name:
Apoptotic protease-activating factor 1 (APAF-1) ;
Alternative:
Organism:
Dog (Canis familiarisCanis lupus familiaris).
General Annotation
Sub Unit:
Monomer. Oligomerizes upon binding of cytochrome c and dATP. Oligomeric Apaf-1 and pro-caspase-9 bind to each other via their respective NH2-terminal CARD domains and consecutively mature caspase-9 is released from the complex. Interacts with APIP.
Function:
Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase 9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.
Subcellular Location:
N/A
Protein Attributes:
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Mouse
Rat
Human
Dog
Polyclonal Antibody for Dog APAF-1
Polyclonal Antibody for Dog APAF-1
Polyclonal Antibody for Dog APAF-1
Polyclonal Antibody for Dog APAF-1
Monoclonal Antibody for Dog APAF-1
Monoclonal Antibody for Dog APAF-1
Monoclonal Antibody for Dog APAF-1
Monoclonal Antibody for Dog APAF-1
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
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Cited for : NUCLEOTIDE SEQUENCE [GENOMIC DNA]