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Index > Protein center > ARTN(Gene name) > Human
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  • ARTN (Gene name),
  • Artemin (Protein name ),  ARTN_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Related Databases
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  • Gene name:
    ARTN(EVN);
    Protein name:
    Artemin;
    Alternative:
    Neublastin;Enovin;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Homodimer; disulfide-linked.
    Function:
    Ligand for the GFR-alpha-3-RET receptor complex but can also activate the GFR-alpha-1-RET receptor complex. Supports the survival of sensory and sympathetic peripheral neurons in culture and also supports the survival of dopaminergic neurons of the ventral mid-brain.
    Subcellular Location:
    Secreted
    Protein Attributes:
    Sequence length:
    220
    Sequence:
    50:
    MELGLGGLST | LSHCPWPRQQ | PALWPTLAAL | ALLSSVAEAS | LGSAPRSPAP | 
    100:
    REGPPPVLAS | PAGHLPGGRT | ARWCSGRARR | PPPQPSRPAP | PPPAPPSALP | 
    150:
    RGGRAARAGG | PGSRARAAGA | RGCRLRSQLV | PVRALGLGHR | SDELVRFRFC | 
    200:
    SGSCRRARSP | HDLSLASLLG | AGALRPPPGS | RPVSQPCCRP | TRYEAVSFMD | 
    220:
    VNSTWRTVDR | LSATACGCLG | 
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    KEGG:
    Pfam:
    SMR:
    UniGene:
    String:
    MIM:
    Uniprot:
     
    FOR
    ELISA Kit for Human Artemin
    Cat.:
    E2069h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Human Artemin
    Cat.:
    E2069m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Human Artemin
    Cat.:
    E2069r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human Artemin
    Cat.:
    U2069m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Artemin
    Cat.:
    U2069r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Artemin
    Cat.:
    U2069h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Human Artemin
    Cat.:
    P2069Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Artemin
    Cat.:
    P2069Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Artemin
    Cat.:
    P2069Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human Artemin
    Monoclonal Antibody for Human Artemin
    Monoclonal Antibody for Human Artemin
    Protein for Human Artemin
    Protein for Human Artemin
    Protein for Human Artemin

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Artemin, a novel member of the GDNF ligand family, supports peripheral and central neurons and signals through the GFRalpha3-RET receptor complex."
      Baloh R.H. , Tansey M.G. , Lampe P.A. , Fahrner T.J. , Enomoto H. , Simburger K.S. , Leitner M.L. , Araki T. , Johnson E.M. Jr. , Milbrandt J.
      Neuron21:1291-1302(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA] (ISOFORMS 1 AND 2);FUNCTION;TISSUE SPECIFICITY;DEVELOPMENTAL STAGE;VARIANT ARG-19
    2. 2.
      "Enovin, a member of the glial cell-line-derived neurotrophic factor (GDNF) family with growth promoting activity on neuronal cells. Existence and tissue-specific expression of different splice variants."
      Masure S. , Geerts H. , Cik M. , Hoefnagel E. , Van Den Kieboom G. , Tuytelaars A. , Harris S. , Lesage A.S.J. , Leysen J.E. , van der Helm L. , Verhasselt P. , Yon J. , Gordon R.D.
      Eur. J. Biochem.266:892-902(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] (ISOFORMS 1 AND 3);FUNCTION;TISSUE SPECIFICITY;VARIANT ARG-19
    3. 3.
      "In vivo protection of nigral dopamine neurons by lentiviral gene transfer of the novel GDNF-family member neublastin/artemin."
      Rosenblad C. , Gronborg M. , Hansen C. , Blom N. , Meyer M. , Johansen J. , Dago L. , Kirik D. , Patel U.A. , Lundberg C. , Trono D. , Bjoerklund A. , Johansen T.E.
      Mol. Cell. Neurosci.15:199-214(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);VARIANT ARG-19
      tissue: Brain.
    4. 4.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ERRATUM
    5. 5.
      "The DNA sequence and biological annotation of human chromosome 1."
      Gregory S.G. , Barlow K.F. , McLay K.E. , Kaul R. , Swarbreck D. , Dunham A. , Scott C.E. , Howe K.L. , Woodfine K. , Spencer C.C.A. , Jones M.C. , Gillson C. , Searle S. , Zhou Y. , Kokocinski F. , McDonald L. , Evans R. , Phillips K. , more...
      Nature441:315-321(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    6. 6.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    7. 7.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 3)
      tissue: Brain.
    8. 8.
      "Structure of artemin complexed with its receptor GFRalpha3: convergent recognition of glial cell line-derived neurotrophic factors."
      Wang X. , Baloh R.H. , Milbrandt J. , Garcia K.C.
      Structure14:1083-1092(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.92 ANGSTROMS) OF 122-220 IN COMPLEX WITH GFRA3;DISULFIDE BONDS;SUBUNIT
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