Gene name:
ASGR2 (CLEC4H2) ;
Protein name:
Asialoglycoprotein receptor 2 (ASGP-R 2;ASGPR 2) ;
Alternative:
Hepatic lectin H2 (HL-2) ;C-type lectin domain family 4 member H2 ;
Organism:
Human (Homo sapiens).
General Annotation
Sub Unit:
The functioning ligand-binding unit of this receptor is thought to be at least a dimer. Interacts with LASS2.
Function:
Mediates the endocytosis of plasma glycoproteins to which the terminal sialic acid residue on their complex carbohydrate moieties has been removed. The receptor recognizes terminal galactose and N-acetylgalactosamine units. After ligand binding to the receptor, the resulting complex is internalized and transported to a sorting organelle, where receptor and ligand are disassociated. The receptor then returns to the cell membrane surface.
Subcellular Location:
Membrane
Single-pass type II membrane protein
Protein Attributes:
50:
MAKDFQDIQQ | LSSEENDHPF | HQGEGPGTRR | LNPRRGNPFL | KGPPPAQPLA |
100:
QRLCSMVCFS | LLALSFNILL | LVVICVTGSQ | SEGHGGAQLQ | AELRSLKEAF |
150:
SNFSSSTLTE | VQAISTHGGS | VGDKITSLGA | KLEKQQQDLK | ADHDALLFHL |
200:
KHFPVDLRFV | ACQMELLHSN | GSQRTCCPVN | WVEHQGSCYW | FSHSGKAWAE |
250:
AEKYCQLENA | HLVVINSWEE | QKFIVQHTNP | FNTWIGLTDS | DGSWKWVDGT |
300:
DYRHNYKNWA | VTQPDNWHGH | ELGGSEDCVE | VQPDGRWNDD | FCLQVYRWVC |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Rat
Mouse
ELISA Kit for Human ASGP-R 2
ELISA Kit for Human ASGP-R 2
ELISA Kit for Human ASGP-R 2
CLIA Kit for Human ASGP-R 2
CLIA Kit for Human ASGP-R 2
CLIA Kit for Human ASGP-R 2
Polyclonal Antibody for Human ASGP-R 2
Polyclonal Antibody for Human ASGP-R 2
Polyclonal Antibody for Human ASGP-R 2
Monoclonal Antibody for Human ASGP-R 2
Monoclonal Antibody for Human ASGP-R 2
Monoclonal Antibody for Human ASGP-R 2
Protein for Human ASGP-R 2
Protein for Human ASGP-R 2
Protein for Human ASGP-R 2
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);VARIANT ARG-85
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);VARIANT ARG-85
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA];VARIANT ARG-85
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-102
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Plasma .
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-102 AND ASN-170
tissue :
Liver .