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Index > Protein center > Acvr2a(Gene name) > Mouse
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  • Acvr2a (Gene name),
  • Activin receptor type-2A (Protein name ),  AVR2A_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Acvr2a(Acvr2);
    Protein name:
    Activin receptor type-2A;
    Alternative:
    Activin receptor type IIA(ACTR-IIA);
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Interacts with AIP1. Part of a complex consisting of AIP1, ACVR2A, ACVR1B and SMAD3.
    Function:
    On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for activin A, activin B and inhibin A.
    Subcellular Location:
    Membrane Single-pass type I membrane protein
    Protein Attributes:
    Sequence length:
    513
    Sequence:
    50:
    MGAAAKLAFA | VFLISCSSGA | ILGRSETQEC | LFFNANWERD | RTNQTGVEPC | 
    100:
    YGDKDKRRHC | FATWKNISGS | IEIVKQGCWL | DDINCYDRTD | CIEKKDSPEV | 
    150:
    YFCCCEGNMC | NEKFSYFPEM | EVTQPTSNPV | TPKPPYYNIL | LYSLVPLMLI | 
    200:
    AGIVICAFWV | YRHHKMAYPP | VLVPTQDPGP | PPPSPLLGLK | PLQLLEVKAR | 
    250:
    GRFGCVWKAQ | LLNEYVAVKI | FPIQDKQSWQ | NEYEVYSLPG | MKHENILQFI | 
    300:
    GAEKRGTSVD | VDLWLITAFH | EKGSLSDFLK | ANVVSWNELC | HIAETMARGL | 
    350:
    AYLHEDIPGL | KDGHKPAISH | RDIKSKNVLL | KNNLTACIAD | FGLALKFEAG | 
    400:
    KSAGDTHGQV | GTRRYMAPEV | LEGAINFQRD | AFLRIDMYAM | GLVLWELASR | 
    450:
    CTAADGPVDE | YMLPFEEEIG | QHPSLEDMQE | VVVHKKKRPV | LRDYWQKHAG | 
    500:
    MAMLCETIEE | CWDHDAEARL | SAGCVGERIT | QMQRLTNIIT | TEDIVTVVTM | 
    513:
    VTNVDFPPKE | SSL
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
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    Related Databases
    String:
    KEGG:
    SMR:
    UniGene:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse Activin receptor type-2A
    Cat.:
    E9516m
    Price:
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    MSDS:
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    Packing:
    96T
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    ELISA Kit for Mouse Activin receptor type-2A
    Cat.:
    E9516h
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    MSDS:
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    Packing:
    96T
    ELISA Kit for Mouse Activin receptor type-2A
    Cat.:
    E9516r
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    MSDS:
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    Packing:
    96T
    ELISA Kit for Mouse Activin receptor type-2A
    Cat.:
    E9516b
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    MSDS:
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    Packing:
    96T
    ELISA Kit for Mouse Activin receptor type-2A
    Cat.:
    E9516c
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Mouse Activin receptor type-2A
    Cat.:
    U9516c
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Activin receptor type-2A
    Cat.:
    U9516b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Activin receptor type-2A
    Cat.:
    U9516m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Activin receptor type-2A
    Cat.:
    U9516r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Activin receptor type-2A
    Cat.:
    U9516h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Mouse Activin receptor type-2A
    Polyclonal Antibody for Mouse Activin receptor type-2A
    Polyclonal Antibody for Mouse Activin receptor type-2A
    Cat.:
    P9516Rb-r
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse Activin receptor type-2A
    Cat.:
    P9516Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse Activin receptor type-2A
    Cat.:
    P9516Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Mouse Activin receptor type-2A
    Monoclonal Antibody for Mouse Activin receptor type-2A
    Monoclonal Antibody for Mouse Activin receptor type-2A
    Monoclonal Antibody for Mouse Activin receptor type-2A
    Monoclonal Antibody for Mouse Activin receptor type-2A
    Protein for Mouse Activin receptor type-2A
    Protein for Mouse Activin receptor type-2A
    Protein for Mouse Activin receptor type-2A
    Protein for Mouse Activin receptor type-2A
    Protein for Mouse Activin receptor type-2A

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Expression cloning of an activin receptor, a predicted transmembrane serine kinase."
      Mathews L.S. , Vale W.W.
      Cell65:973-982(1991) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    2. 2.
      "Three-finger toxin fold for the extracellular ligand-binding domain of the type II activin receptor serine kinase."
      Greenwald J. , Fischer W.H. , Vale W.W. , Choe S.
      Nat. Struct. Biol.6:18-22(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.5 ANGSTROMS) OF 25-121
    3. 3.
      "The disulfide bond arrangement in the extracellular domain of the activin type II receptor."
      Fischer W.H. , Greenwald J. , Park M. , Craig A.G. , Choe S. , Vale W.
      J. Protein Chem.18:437-446(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: DISULFIDE BONDS IN EXTRACELLULAR DOMAIN
    4. 4.
      "Identification and characterization of a PDZ protein that interacts with activin types II receptors."
      Shoji H. , Tsuchida K. , Kishi H. , Yamakawa N. , Matsuzaki T. , Liu Z. , Nakamura T. , Sugino H.
      J. Biol. Chem.275:5485-5492(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH AIP1;IDENTIFICATION IN A COMPLEX WITH ACVR1B; AIP1 AND SMAD3
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