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Index > Protein center > Bcl11a(Gene name) > Mouse
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  • Bcl11a (Gene name),
  • B-cell lymphoma/leukemia 11A (Protein name ),  BC11A_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    Bcl11a(Ctip1;Evi9;Kiaa1809);
    Protein name:
    B-cell lymphoma/leukemia 11A(BCL-11A);
    Alternative:
    COUP-TF-interacting protein 1;B-cell CLL/lymphoma 11A;Ecotropic viral integration site 9 protein(EVI-9);
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Interacts with TFCOUP1, PIAS3, ARP1 and EAR2.
    Function:
    Functions as a myeloid and B-cell proto-oncogene. May play important roles in leukemogenesis and hematopoiesis. An essential factor in lymphopoiesis, is required for B-cell formation in fetal liver. May function as a modulator of the transcriptional repression activity of ARP1.
    Subcellular Location:
    Cytoplasm Nucleus Associates with the nuclear body. Colocalizes with SUMO1 and SENP2 in nuclear speckles.
    Protein Attributes:
    Sequence length:
    773
    Sequence:
    50:
    MSRRKQGKPQ | HLSKREFSPE | PLEAILTDDE | PDHGPLGAPE | GDHDLLTCGQ | 
    100:
    CQMNFPLGDI | LIFIEHKRKQ | CNGSLCLEKG | VDKPPSPSPI | EMKKASNPVE | 
    150:
    VGIQVTPEDD | DCLSTSSRGI | CPKQEHIADK | LLHWRGLSSP | RSAHGALIPT | 
    200:
    PGMSAEYAPQ | GICKDEPSSY | TCTTCKQPFT | SAWFLLQHAQ | NTHGLRIYLE | 
    250:
    SEHGSPLTPR | VGIPSGLGAE | CPSQPPLHGI | HIADNNPFNL | LRIPGSVSRE | 
    300:
    ASGLAEGRFP | PTPPLFSPPP | RHHLDPHRIE | RLGAEEMALA | THHPSAFDRV | 
    350:
    LRLNPMAMEP | PAMDFSRRLR | ELAGNTSSPP | LSPGRPSPMQ | RLLQPFQPGS | 
    400:
    KPPFLATPPL | PPLQSAPPPS | QPPVKSKSCE | FCGKTFKFQS | NLVVHRRSHT | 
    450:
    GEKPYKCNLC | DHACTQASKL | KRHMKTHMHK | SSPMTVKSDD | GLSTASSPEP | 
    500:
    GTSDLVGSAS | SALKSVVAKF | KSENDPNLIP | ENGDEEEEED | DEEEEEEEEE | 
    550:
    EEEELTESER | VDYGFGLSLE | AARHHENSSR | GAVVGVGDEG | RALPDVMQGM | 
    600:
    VLSSMQHFSE | AFHQVLGEKH | KRSHLAEAEG | HRDTCDEDSV | AGESDRIDDG | 
    650:
    TVNGRGCSPG | ESASGGLSKK | LLLGSPSSLS | PFSKRIKLEK | EFDLPPAAMP | 
    700:
    NTENVYSQWL | AGYAASRQLK | DPFLTFGDSR | QSPFASSSEH | SSENGSLRFS | 
    750:
    TPPGELDGGI | SGRSGTGSGG | STPHISGPGP | GRPSSKEGRR | SDTCPSHTPV | 
    773:
    RRSTPRAQDV | WQFSDGSSRT | LKF
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    SMR:
    UniGene:
    KEGG:
    Pfam:
    UniGene:
    String:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse BCL-11A
    Cat.:
    E14965h
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    Packing:
    96T
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    ELISA Kit for Mouse BCL-11A
    Cat.:
    E14965m
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Mouse BCL-11A
    Cat.:
    U14965h
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse BCL-11A
    Cat.:
    U14965m
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    MSDS:
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    Packing:
    96T
    Polyclonal Antibody for Mouse BCL-11A
    Cat.:
    P14965Rb-m
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse BCL-11A
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    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Mouse BCL-11A
    Monoclonal Antibody for Mouse BCL-11A
    Protein for Mouse BCL-11A
    Protein for Mouse BCL-11A

    R&D Technical Data
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    Precision
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    Recovery
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Linearity
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    References
    1. 1.
      "Evi9 encodes a novel zinc finger protein that physically interacts with BCL6, a known human B-cell proto-oncogene product."
      Nakamura T. , Yamazaki Y. , Saiki Y. , Moriyama M. , Largaespada D.A. , Jenkins N.A. , Copeland N.G.
      Mol. Cell. Biol.20:3178-3186(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1; 2 AND 3)
      strain: BXH/2.
    2. 2.
      "Isolation of a novel family of C(2)H(2) zinc finger proteins implicated in transcriptional repression mediated by chicken ovalbumin upstream promoter transcription factor (COUP-TF) orphan nuclear receptors."
      Avram D. , Fields A. , Pretty On Top K. , Nevrivy D.J. , Ishmael J.E. , Leid M.
      J. Biol. Chem.275:10315-10322(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);INTERACTION WITH TFCOUP1; EAR2 AND ARP1
      strain: BALB/c.
      tissue: Brain.
    3. 3.
      "The transcriptional landscape of the mammalian genome."
      Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
      Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 4; 5 AND 6)
      strain: C57BL/6J.
      tissue: Brain.
      tissue: Brain cortex.
      tissue: Corpora quadrigemina.
      tissue: Embryo.
      tissue: Spinal cord.
    4. 4.
      "Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries."
      Okazaki N. , Kikuno R. , Ohara R. , Inamoto S. , Aizawa H. , Yuasa S. , Nakajima D. , Nagase T. , Ohara O. , Koga H.
      DNA Res.10:35-48(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 7)
      tissue: Brain.
    5. 5.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 5 AND 8)
      strain: FVB/N-3.
      tissue: Mammary tumor.
    6. 6.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
    7. 7.
      "BCL11A is a SUMOylated protein and recruits SUMO-conjugation enzymes in its nuclear body."
      Kuwata T. , Nakamura T.
      Genes Cells13:931-940(2008) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUMOYLATION AT LYS-634;INTERACTION WITH PIAS3;SUBCELLULAR LOCATION;MUTAGENESIS OF LYS-123 AND LYS-637
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