CPB2 ELISA Kit for Human(Homo sapiens) | EIAab.comCPB2 ELISA Kit for Human(Homo sapiens)

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Index > Protein center > CPB2(Gene name) > Human

CPB2 (Gene name),

Carboxypeptidase B2 (Protein name ), CBPB2_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

CPB2;

Protein name:

Carboxypeptidase B2;

Alternative:

Plasma carboxypeptidase B(pCPB);Carboxypeptidase U(CPU);Thrombin-activable fibrinolysis inhibitor(TAFI);

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

N/A

Function:

Cleaves C-terminal arginine or lysine residues from biologically active peptides such as kinins or anaphylatoxins in the circulation thereby regulating their activities. Down-regulates fibrinolysis by removing C-terminal lysine residues from fibrin that has already been partially degraded by plasmin.

Subcellular Location:

Secreted

Protein Attributes:

Sequence length:

423

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

423:

IKPTCREAFA | AVSKIAWHVI | RNV

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

String:

Q96IY4

Pfam:

PF00246

KEGG:

hsa:1361

SMR:

Q96IY4

UniGene:

Hs.512937

STRING:

9606.ENSP00000181383

MIM:

603101

Uniprot:

Q96IY4

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ELISA Kit for Human Carboxypeptidase B2

Cat.:

E0615h

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96T

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ELISA Kit for Human Carboxypeptidase B2

Cat.:

E0615m

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96T

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ELISA Kit for Human Carboxypeptidase B2

Cat.:

E0615r

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Packing:

96T

ELISA Kit for Human Carboxypeptidase B2

Cat.:

E0615b

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Packing:

96T

CLIA Kit for Human Carboxypeptidase B2

Cat.:

U0615m

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Packing:

96T

CLIA Kit for Human Carboxypeptidase B2

Cat.:

U0615r

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96T

CLIA Kit for Human Carboxypeptidase B2

Cat.:

U0615b

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Packing:

96T

CLIA Kit for Human Carboxypeptidase B2

Cat.:

U0615h

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96T

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Polyclonal Antibody for Human Carboxypeptidase B2

Cat.:

P0615Rb-h

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Packing:

40ug/0.2ml

Polyclonal Antibody for Human Carboxypeptidase B2

Cat.:

P0615Rb-m

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40ug/0.2ml

Polyclonal Antibody for Human Carboxypeptidase B2

Cat.:

P0615Rb-r

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Packing:

40ug/0.2ml

Monoclonal Antibody for Human Carboxypeptidase B2

Protein for Human Carboxypeptidase B2

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

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References

1.

"Isolation, molecular cloning, and partial characterization of a novel carboxypeptidase B from human plasma."
Eaton D.L. , Malloy B.E. , Tsai S.P. , Henzel W. , Drayna D.
J. Biol. Chem.266:21833-21838(1991) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);PARTIAL PROTEIN SEQUENCE;INTERACTION WITH PLASMINOGEN;VARIANTS THR-169 AND THR-347
tissue: Liver.
2.

"Isolation, molecular cloning, and partial characterization of a novel carboxypeptidase B from human plasma."
Matsumoto A.
Submitted (1998-03) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2)
3.

"Cloning of human full-length CDSs in BD Creator(TM) system donor vector."
Kalnine N. , Chen X. , Rolfs A. , Halleck A. , Hines L. , Eisenstein S. , Koundinya M. , Raphael J. , Moreira D. , Kelley T. , LaBaer J. , Lin Y. , Phelan M. , Farmer A.
Submitted (2003-05) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1);VARIANT THR-347
4.

"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1);VARIANTS THR-169 AND THR-347
tissue: Liver.
5.

SeattleSNPs variation discovery resource
Submitted (2004-08) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];VARIANT THR-347
6.

"The DNA sequence and analysis of human chromosome 13."
Dunham A. , Matthews L.H. , Burton J. , Ashurst J.L. , Howe K.L. , Ashcroft K.J. , Beare D.M. , Burford D.C. , Hunt S.E. , Griffiths-Jones S. , Jones M.C. , Keenan S.J. , Oliver K. , Scott C.E. , Ainscough R. , Almeida J.P. , Ambrose K.D. , Andrews D.T. , more...
Nature428:522-528(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
7.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1);VARIANT THR-347
tissue: Skeletal muscle.
8.

"Characterization of plasmin-mediated activation of plasma procarboxypeptidase B. Modulation by glycosaminoglycans."
Mao S.S. , Cooper C.M. , Wood T. , Shafer J.A. , Gardell S.J.
J. Biol. Chem.274:35046-35052(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;CATALYTIC ACTIVITY
9.

"Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry."
Liu T. , Qian W.-J. , Gritsenko M.A. , Camp D.G. II , Monroe M.E. , Moore R.J. , Smith R.D.
J. Proteome Res.4:2070-2080(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-44; ASN-73 AND ASN-108
tissue: Plasma.
10.

"Post-translational modifications of human thrombin-activatable fibrinolysis inhibitor (TAFI): evidence for a large shift in the isoelectric point and reduced solubility upon activation."
Valnickova Z. , Christensen T. , Skottrup P. , Thogersen I.B. , Hojrup P. , Enghild J.J.
Biochemistry45:1525-1535(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION AT ASN-44; ASN-73; ASN-85; ASN-108 AND ASN-241;DISULFIDE BONDS
11.

"Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry."
Chen R. , Jiang X. , Sun D. , Han G. , Wang F. , Ye M. , Wang L. , Zou H.
J. Proteome Res.8:651-661(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-108
tissue: Liver.
12.

"Human urinary glycoproteomics; attachment site specific analysis of N-and O-linked glycosylations by CID and ECD."
Halim A. , Nilsson J. , Ruetschi U. , Hesse C. , Larson G.
Mol. Cell. Proteomics0:0-0(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION AT ASN-108;STRUCTURE OF CARBOHYDRATES;IDENTIFICATION BY MASS SPECTROMETRY
13.

"Crystal structures of TAFI elucidate the inactivation mechanism of activated TAFI: a novel mechanism for enzyme autoregulation."
Marx P.F. , Brondijk T.H. , Plug T. , Romijn R.A. , Hemrika W. , Meijers J.C. , Huizinga E.G.
Blood112:2803-2809(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.8 ANGSTROMS) OF 24-423 ALONE AND IN COMPLEX WITH INHIBITOR;GLYCOSYLATION AT ASN-44; ASN-73; ASN-85 AND ASN-108;ACTIVE SITE;ZINC-BINDING SITES;ENZYME REGULATION;DISULFIDE BONDS
14.

"Insights into the molecular inactivation mechanism of human activated thrombin-activatable fibrinolysis inhibitor."
Sanglas L. , Arolas J.L. , Valnickova Z. , Aviles F.X. , Enghild J.J. , Gomis-Ruth F.X.
J. Thromb. Haemost.8:1056-1065(2010) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.5 ANGSTROMS) OF 115-423 IN COMPLEX WITH INHIBITOR;DISULFIDE BONDS

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