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Index > Protein center > Ccl12(Gene name) > Mouse
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  • Ccl12 (Gene name),
  • C-C motif chemokine 12 (Protein name ),  CCL12_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    Ccl12(Mcp5;Scya12);
    Protein name:
    C-C motif chemokine 12;
    Alternative:
    Monocyte chemoattractant protein 5;MCP-1-related chemokine;Small-inducible cytokine A12;Monocyte chemotactic protein 5(MCP-5);
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Homodimer.
    Function:
    Chemotactic factor that attracts eosinophils, monocytes, and lymphocytes but not neutrophils. Potent monocyte active chemokine that signals through CCR2. Involved in allergic inflammation and the host response to pathogens and may play a pivotal role during early stages of allergic lung inflammation.
    Subcellular Location:
    Secreted
    Protein Attributes:
    Sequence length:
    104
    Sequence:
    50:
    MKISTLLCLL | LIATTISPQV | LAGPDAVSTP | VTCCYNVVKQ | KIHVRKLKSY | 
    100:
    RRITSSQCPR | EAVIFRTILD | KEICADPKEK | WVKNSINHLD | KTSQTFILEP | 
    104:
    SCLG
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    Pfam:
    UniGene:
    SMR:
    String:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse C-C motif chemokine 12
    Cat.:
    E0442m
    Price:
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    MSDS:
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    Packing:
    96T
    Range:
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    CLIA Kit for Mouse C-C motif chemokine 12
    Cat.:
    U0442m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Mouse C-C motif chemokine 12
    Cat.:
    P0442Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Mouse C-C motif chemokine 12
    Protein for Mouse C-C motif chemokine 12

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    References
    1. 1.
      "Distinct expression and function of the novel mouse chemokine monocyte chemotactic protein-5 in lung allergic inflammation."
      Jia G.-Q. , Gonzalo J.A. , Lloyd C. , Kremer L. , Lu L. , Martinez A.C. , Wershil B.K. , Gutierrez-Ramos J.-C.
      J. Exp. Med.184:1939-1951(1996) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    2. 2.
      "Murine monocyte chemoattractant protein (MCP)-5: a novel CC chemokine that is a structural and functional homologue of human MCP-1."
      Sarafi M.N. , Garcia-Zepeda E.A. , MacLean J.A. , Charo I.F. , Luster A.D.
      J. Exp. Med.185:99-109(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    3. 3.
      "Sequence polymorphisms in the chemokines Scya1 (TCA-3), Scya2 (monocyte chemoattractant protein (MCP)-1), and Scya12 (MCP-5) are candidates for eae7, a locus controlling susceptibility to monophasic remitting/nonrelapsing experimental allergic encephalomyelitis."
      Teuscher C. , Butterfield R.J. , Ma R.Z. , Zachary J.F. , Doerge R.W. , Blankenhorn E.P.
      J. Immunol.163:2262-2266(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      strain: B10.S/J.
      strain: BALB/c.
      strain: DBA/2J.
      strain: NOD/LtJ.
      strain: SJL/J.
      tissue: Spleen.
    4. 4.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Mammary gland.
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