CD79A ELISA Kit for Bovine(Bos taurus) | EIAab.comCD79A ELISA Kit for Bovine(Bos taurus)

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CD79A (Gene name),

B-cell antigen receptor complex-associated protein alpha chain (Protein name ), CD79A_BOVIN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

CD79A(IGA;MB-1);

Protein name:

B-cell antigen receptor complex-associated protein alpha chain;

Alternative:

MB-1 membrane glycoprotein;Ig-alpha;Surface IgM-associated protein;Membrane-bound immunoglobulin-associated protein;

CD:

CD79a;

Organism:

Bovine (Bos taurus).

General Annotation

Sub Unit:

Heterodimer of alpha and beta chains; disulfide-linked. Part of the B-cell antigen receptor complex where the alpha/beta chain heterodimer is non-covalently associated with an antigen-specific membrane-bound surface immunoglobulin of two heavy chains and two light chains. Interacts through its phosphorylated ITAM domain with the SH2 domains of SYK which stimulates SYK autophosphorylation and activation. Also interacts, when phosphorylated on Tyr-207, with the SH2 domain of BLNK/SLP65, bringing BLNK into proximity with SYK and allowing SYK to phosphorylate BLNK which is necessary for trafficking of the BCR to late endosomes. Interacts with Src-family tyrosine kinases including FYN and LYN, increasing their activity.

Function:

Required in cooperation with CD79B for initiation of the signal transduction cascade activated by binding of antigen to the B-cell antigen receptor complex (BCR) which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. Also required for BCR surface expression and for efficient differentiation of pro- and pre-B-cells. Stimulates SYK autophosphorylation and activation. Binds to BLNK, bringing BLNK into proximity with SYK and allowing SYK to phosphorylate BLNK. Also interacts with and increases activity of some Src-family tyrosine kinases. Represses BCR signaling during development of immature B cells.

Subcellular Location:

Cell membrane Single-pass type I membrane protein Following antigen binding, the BCR has been shown to translocate from detergent-soluble regions of the cell membrane to lipid rafts although signal transduction through the complex can also occur outside lipid rafts.

Protein Attributes:

Sequence length:

223

Sequence:

50:

100:

150:

200:

223:

RGLQGTYQDV | GSLHIGDAQL | EKP

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

Pfam:

PF07679

String:

P40293

KEGG:

bta:281674

UniGene:

Bt.4436

Uniprot:

P40293

FOR

ELISA Kit for Bovine B-cell antigen receptor complex-associated protein alpha chain

Cat.:

E15278d

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MSDS:

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Packing:

96T

ELISA Kit for Bovine B-cell antigen receptor complex-associated protein alpha chain

Cat.:

E15278b

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Packing:

96T

ELISA Kit for Bovine B-cell antigen receptor complex-associated protein alpha chain

Cat.:

E15278m

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MSDS:

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Packing:

96T

ELISA Kit for Bovine B-cell antigen receptor complex-associated protein alpha chain

Cat.:

E15278h

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MSDS:

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Packing:

96T

CLIA Kit for Bovine B-cell antigen receptor complex-associated protein alpha chain

Cat.:

U15278b

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Bovine B-cell antigen receptor complex-associated protein alpha chain

Cat.:

U15278m

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Bovine B-cell antigen receptor complex-associated protein alpha chain

Cat.:

U15278h

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Bovine B-cell antigen receptor complex-associated protein alpha chain

Cat.:

U15278d

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

Polyclonal Antibody for Bovine B-cell antigen receptor complex-associated protein alpha chain

Cat.:

P15278Rb-m

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Packing:

40ug/0.2ml

Polyclonal Antibody for Bovine B-cell antigen receptor complex-associated protein alpha chain

Cat.:

P15278Rb-h

Price:

Please sign in first.

Packing:

40ug/0.2ml

Polyclonal Antibody for Bovine B-cell antigen receptor complex-associated protein alpha chain

Monoclonal Antibody for Bovine B-cell antigen receptor complex-associated protein alpha chain

Protein for Bovine B-cell antigen receptor complex-associated protein alpha chain

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

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Linearity

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References

1.

"Two forms of the mb-1 gene transcript in cattle."
Youn H.-Y. , Goitsuka R. , Okuda M. , Watari T. , Tsujimoto H. , Hasegawa A.
J. Immunol.153:5127-5132(1994) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1 AND 2)
tissue: Leukocyte.
tissue: Lymphoblast.
2.

"Molecular cloning of bovine mb-1 cDNA."
Youn H.-Y. , Goitsuka R. , Kato H. , Mason D.Y. , Watari T. , Tsujimoto H. , Hasegawa A.
Vet. Immunol. Immunopathol.52:191-200(1996) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
3.

NIH - Mammalian Gene Collection (MGC) project
Submitted (2006-08) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
strain: Hereford.
tissue: Thymus.

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