Protein name:
Acidic mammalian chitinase (AMCase) ;
Alternative:
Organism:
Rat (Rattus norvegicus).
General Annotation
Sub Unit:
Interacts with EGFR.
Function:
Degrades chitin and chitotriose. May participate in the defense against nematodes, fungi and other pathogens. Plays a role in T helper cell type 2 (Th2) immune response. Contributes to the response to IL-13 and inflammation in response to IL-13. Stimulates chemokine production by pulmonary epithelial cells. Protects lung epithelial cells against apoptosis and promotes phosphorylation of AKT1. Its function in the inflammatory response and in protecting cells against apoptosis is inhibited by allosamidin, suggesting that the function of this protein depends on carbohydrate binding.
Subcellular Location:
Cytoplasm
Secreted
Protein Attributes:
50:
MAKLILVTGL | VLLLNVQLGS | AYNLVCYFTN | WAQYRPGLGS | FKPDDINPCL |
100:
CTHLIYAFAG | MQNNQITTIE | WNDVTLYKAF | NDLKNRNSKL | KTLLAIGGWN |
150:
FGTAPFTTMV | STSQNRQTFI | TSVIKFLRQY | GFDGLDLDWE | YPGSRGSPPQ |
200:
DKHLFTVLVK | ELREAFEQEA | IESNRPRLMV | TAAVAAGISN | IQAGYEIPEL |
250:
SQYLDFIHVM | TYDLHGSWDG | YTGENSPLYK | LPTETGSNAY | LNVDYVMNYW |
300:
KDNGAPAEKL | IVGFPEYGHT | YILSNPSDTG | IGAPTSGNGP | AGPYTRQAGF |
350:
WAYYEICTFL | RNGATQDWDA | PQEVPYAYKG | NEWVGYDNIK | SFSVKAQWLK |
400:
QNNFGGAMIW | AIDLDDFTGS | FCDQGKFPLT | STLNKALDIP | TAGCTAPDLP |
450:
SEPVTTPPGS | GSGGGSSGGG | SEGSGFCAGK | ADGLYPVADD | RNAFWHCING |
473:
ITYQQHCQAG | LVFDTSCNCC | NWP
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Mouse
Human
Rat
Bovine
Polyclonal Antibody for Rat AMCase
Polyclonal Antibody for Rat AMCase
Polyclonal Antibody for Rat AMCase
Polyclonal Antibody for Rat AMCase
Monoclonal Antibody for Rat AMCase
Monoclonal Antibody for Rat AMCase
Monoclonal Antibody for Rat AMCase
Monoclonal Antibody for Rat AMCase
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
"Rattus norvegicus similar to acidic mammalian chitinase precursor."
Chen X.-H.
,
Cai G.-P.
Submitted (2003-11) to the EMBL/GenBank/DDBJ databases
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
strain :
Sprague-Dawley .
tissue :
Stomach .