Gene name:
STUB1 (RCJMB04_32b21) ;
Protein name:
STIP1 homology and U box-containing protein 1 ;
Alternative:
Organism:
Chicken (Gallus gallus).
General Annotation
Sub Unit:
Homodimer (By similarity). Interacts with BAG2, and with the E2 ubiquitin conjugating enzymes UBE2D1, UBE2D2 and UBE2D3. Interacts with the C-terminal domains of HSPA8 and HSPA1A. Detected in a ternary complex containing STUB1, HSPA1A and HSPBP1.
Function:
E3 ubiquitin-protein ligase which targets misfolded chaperone substrates towards proteasomal degradation. Ubiquitinates NOS1 in concert with Hsp70 and Hsp40. Mediates polyubiquitination of DNA polymerase beta (POLB), thereby playing a role in base-excision repair: catalyzes polyubiquitination by amplifying the HUWE1/ARF-BP1-dependent monoubiquitination and leading to POLB-degradation by the proteasome. Mediates polyubiquitination of CYP3A4. May ubiquitinate EPHA2 and regulate the receptor stability and activity through proteasomal degradation.
Subcellular Location:
Cytoplasm
Protein Attributes:
50:
MKGKEERERE | GGGGAVGPGA | AGPGAGGGSP | EKSHSAQEHK | EQGNRLFGGR |
100:
KYPEAAAAYG | RAINRNPLVA | VYYTNRALCY | LKMQQHDKAL | ADCKRALELD |
150:
GQSVKAHFFL | GQCQMEMENY | DEAIANLQRA | YNLAKEQRLN | FGDDIPSALR |
200:
IAKKKRWNSI | EEKRINQENE | LHSYLTRLIM | AEKERELAEC | RKAQQEENVD |
250:
ESRGRVQLAG | IEAKHDKYLA | DMDELFSQVD | EKRKKRDIPD | YLCGKISFEL |
300:
MREPCITPSG | ITYDRKDIEE | HLQRVGHFDP | VTRSPLTQDQ | LIPNLAMKEV |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Mouse
Chicken
ELISA Kit for Chicken STIP1 homology and U box-containing protein 1
ELISA Kit for Chicken STIP1 homology and U box-containing protein 1
ELISA Kit for Chicken STIP1 homology and U box-containing protein 1
CLIA Kit for Chicken STIP1 homology and U box-containing protein 1
CLIA Kit for Chicken STIP1 homology and U box-containing protein 1
CLIA Kit for Chicken STIP1 homology and U box-containing protein 1
Polyclonal Antibody for Chicken STIP1 homology and U box-containing protein 1
Polyclonal Antibody for Chicken STIP1 homology and U box-containing protein 1
Polyclonal Antibody for Chicken STIP1 homology and U box-containing protein 1
Monoclonal Antibody for Chicken STIP1 homology and U box-containing protein 1
Monoclonal Antibody for Chicken STIP1 homology and U box-containing protein 1
Monoclonal Antibody for Chicken STIP1 homology and U box-containing protein 1
Protein for Chicken STIP1 homology and U box-containing protein 1
Protein for Chicken STIP1 homology and U box-containing protein 1
Protein for Chicken STIP1 homology and U box-containing protein 1
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
"Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis."
Caldwell R.B.
,
Kierzek A.M.
,
Arakawa H.
,
Bezzubov Y.
,
Zaim J.
,
Fiedler P.
,
Kutter S.
,
Blagodatski A.
,
Kostovska D.
,
Koter M.
,
Plachy J.
,
Carninci P.
,
Hayashizaki Y.
,
Buerstedde J.-M.
Genome Biol.6:R6.1-R6.9(2005)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
strain :
CB .
tissue :
Bursa of Fabricius .