Protein name:
Ephrin type-B receptor 6 ;
Alternative:
Tyrosine-protein kinase-defective receptor EPH-6 ;HEP ;
Organism:
Human (Homo sapiens).
General Annotation
Sub Unit:
Interacts with CBL and EPHB1. Interacts with FYN; this interaction takes place in a ligand-independent manner.
Function:
Kinase-defective receptor for members of the ephrin-B family. Binds to ephrin-B1 and ephrin-B2. Modulates cell adhesion and migration by exerting both positive and negative effects upon stimulation with ephrin-B2. Inhibits JNK activation, T cell receptor-induced IL-2 secretion and CD25 expression upon stimulation with ephrin-B2.
Subcellular Location:
Isoform 3
Secreted
Protein Attributes:
50:
MATEGAAQLG | NRVAGMVCSL | WVLLLVSSVL | ALEEVLLDTT | GETSEIGWLT |
100:
YPPGGWDEVS | VLDDQRRLTR | TFEACHVAGA | PPGTGQDNWL | QTHFVERRGA |
150:
QRAHIRLHFS | VRACSSLGVS | GGTCRETFTL | YYRQAEEPDS | PDSVSSWHLK |
200:
RWTKVDTIAA | DESFPSSSSS | SSSSSSAAWA | VGPHGAGQRA | GLQLNVKERS |
250:
FGPLTQRGFY | VAFQDTGACL | ALVAVRLFSY | TCPAVLRSFA | SFPETQASGA |
300:
GGASLVAAVG | TCVAHAEPEE | DGVGGQAGGS | PPRLHCNGEG | KWMVAVGGCR |
350:
CQPGYQPARG | DKACQACPRG | LYKSSAGNAP | CSPCPARSHA | PNPAAPVCPC |
400:
LEGFYRASSD | PPEAPCTGPP | SAPQELWFEV | QGSALMLHWR | LPRELGGRGD |
450:
LLFNVVCKEC | EGRQEPASGG | GGTCHRCRDE | VHFDPRQRGL | TESRVLVGGL |
500:
RAHVPYILEV | QAVNGVSELS | PDPPQAAAIN | VSTSHEVPSA | VPVVHQVSRA |
550:
SNSITVSWPQ | PDQTNGNILD | YQLRYYDQAE | DESHSFTLTS | ETNTATVTQL |
600:
SPGHIYGFQV | RARTAAGHGP | YGGKVYFQTL | PQGELSSQLP | ERLSLVIGSI |
650:
LGALAFLLLA | AITVLAVVFQ | RKRRGTGYTE | QLQQYSSPGL | GVKYYIDPST |
700:
YEDPCQAIRE | LAREVDPAYI | KIEEVIGTGS | FGEVRQGRLQ | PRGRREQTVA |
750:
IQALWAGGAE | SLQMTFLGRA | AVLGQFQHPN | ILRLEGVVTK | SRPLMVLTEF |
800:
MELGPLDSFL | RQREGQFSSL | QLVAMQRGVA | AAMQYLSSFA | FVHRSLSAHS |
850:
VLVNSHLVCK | VARLGHSPQG | PSCLLRWAAP | EVIAHGKHTT | SSDVWSFGIL |
900:
MWEVMSYGER | PYWDMSEQEV | LNAIEQEFRL | PPPPGCPPGL | HLLMLDTWQK |
950:
DRARRPHFDQ | LVAAFDKMIR | KPDTLQAGGD | PGERPSQALL | TPVALDFPCL |
1000:
DSPQAWLSAI | GLECYQDNFS | KFGLCTFSDV | AQLSLEDLPA | LGITLAGHQK |
1021:
KLLHHIQLLQ | QHLRQQGSVE | V
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Rat
Mouse
ELISA Kit for Human Ephrin type-B receptor 6
ELISA Kit for Human Ephrin type-B receptor 6
ELISA Kit for Human Ephrin type-B receptor 6
CLIA Kit for Human Ephrin type-B receptor 6
CLIA Kit for Human Ephrin type-B receptor 6
CLIA Kit for Human Ephrin type-B receptor 6
Polyclonal Antibody for Human Ephrin type-B receptor 6
Polyclonal Antibody for Human Ephrin type-B receptor 6
Polyclonal Antibody for Human Ephrin type-B receptor 6
Monoclonal Antibody for Human Ephrin type-B receptor 6
Monoclonal Antibody for Human Ephrin type-B receptor 6
Monoclonal Antibody for Human Ephrin type-B receptor 6
Protein for Human Ephrin type-B receptor 6
Protein for Human Ephrin type-B receptor 6
Protein for Human Ephrin type-B receptor 6
R&D Technical Data
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Precision
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Recovery
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Linearity
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Cited for : VARIANTS [LARGE SCALE ANALYSIS] SER-122; THR-170; VAL-221; HIS-282; GLN-309; ALA-324; LEU-332; VAL-662; SER-743; HIS-813; LYS-875 AND VAL-993