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Index > Protein center > GPI(Gene name) > Pig
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  • GPI (Gene name),
  • Glucose-6-phosphate isomerase (Protein name ),  G6PI_PIG from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    GPI;
    Protein name:
    Glucose-6-phosphate isomerase(GPI);
    Alternative:
    Neuroleukin(NLK);Autocrine motility factor(AMF);Phosphohexose isomerase(PHI);Phosphoglucose isomerase(PGI);
    Organism:
    Pig (Sus scrofa). 
    General Annotation
    Sub Unit:
    Homodimer in the catalytically active form, monomer in the secreted form.
    Function:
    Besides it's role as a glycolytic enzyme, mammalian GPI can function as a tumor-secreted cytokine and an angiogenic factor (AMF) that stimulates endothelial cell motility. GPI is also a neurotrophic factor (Neuroleukin) for spinal and sensory neurons.
    Subcellular Location:
    Cytoplasm Secreted
    Protein Attributes:
    Sequence length:
    558
    Sequence:
    50:
    MAALTQNPQF | KKLQTWYHEH | RSDLNLRRLF | EGDKDRFNHF | SLNLNTNHGR | 
    100:
    ILLDYSKNLV | TEAVMQMLVD | LAKSRGVEAA | RERMFNGEKI | NFTEDRAVLH | 
    150:
    VALRNRSNTP | ILVDGKDVMP | EVNRVLEKMK | SFCKRVRSGE | WKGYSGKSIT | 
    200:
    DVINIGIGGS | DLGPLMVTEA | LKPYSAEGPR | VWFVSNIDGT | HIAKTLATLN | 
    250:
    PESSLFIIAS | KTFTTQETIT | NAETAKEWFL | QSAKDPSAVA | KHFVALSTNT | 
    300:
    TKVKEFGIDP | QNMFEFWDWV | GGRYSLWSAI | GLSIALHVGF | DNFEQLLSGA | 
    350:
    HWMDQHFRTT | PLEKNAPVLL | ALLGIWYINF | FGCETHAMLP | YDQYLHRFAA | 
    400:
    YFQQGDMESN | GKYITKSGTR | VDHQTGPIVW | GEPGTNGQHA | FYQLIHQGTK | 
    450:
    MIPCDFLIPV | QTQHPIRKGL | HHKILLANFL | AQTEALMKGK | STEEARKELQ | 
    500:
    AAGKSPEDFE | KLLPHKVFEG | NRPTNSIVFT | KLTPFILGAL | IAMYEHKIFV | 
    550:
    QGVIWDINSF | DQWGVELGKQ | LAKKIEPELD | GSSPVTSHDS | STNGLINFIK | 
    558:
    QEREARSQ
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    UniGene:
    SMR:
    Pfam:
    String:
    Uniprot:
     
    FOR
    ELISA Kit for Pig GPI
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    E0725r
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    ELISA Kit for Pig GPI
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    E0725h
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    ELISA Kit for Pig GPI
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    ELISA Kit for Pig GPI
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    E0725p
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    Packing:
    96T
    ELISA Kit for Pig GPI
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    E0725m
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    ELISA Kit for Pig GPI
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    E0725b
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    96T
    CLIA Kit for Pig GPI
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    U0725p
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    96T
    CLIA Kit for Pig GPI
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    U0725r
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Pig GPI
    Cat.:
    U0725h
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Pig GPI
    MSDS:
    Please sign in first.
    CLIA Kit for Pig GPI
    Cat.:
    U0725m
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Pig GPI
    Cat.:
    U0725b
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    Packing:
    96T
    Polyclonal Antibody for Pig GPI
    Cat.:
    P0725Rb-m
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Pig GPI
    Polyclonal Antibody for Pig GPI
    Cat.:
    P0725Rb-h
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Pig GPI
    Polyclonal Antibody for Pig GPI
    Polyclonal Antibody for Pig GPI
    Cat.:
    P0725Rb-r
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    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Pig GPI
    Monoclonal Antibody for Pig GPI
    Monoclonal Antibody for Pig GPI
    Monoclonal Antibody for Pig GPI
    Monoclonal Antibody for Pig GPI
    Monoclonal Antibody for Pig GPI
    Protein for Pig GPI
    Protein for Pig GPI
    Protein for Pig GPI
    Protein for Pig GPI
    Protein for Pig GPI
    Protein for Pig GPI

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    Linearity
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    References
    1. 1.
      "The neurotrophic factor neuroleukin is 90% homologous with phosphohexose isomerase."
      Chaput M. , Claes V. , Portetelle D. , Clutdts I. , Cravador A. , Burny A. , Gras H. , Tartar A.
      Nature332:454-455(1988) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    2. 2.
      Burny A.
      Submitted (1988-08) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SEQUENCE REVISION
    3. 3.
      "Structure of the gene encoding pig phosphoglucose isomerase."
      Claes V. , Kettmann R. , Burny A.
      Gene150:235-241(1994) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
    4. 4.
      "Sequence analysis of the pig phosphoglucose isomerase gene promoter region."
      Claes V. , Taquet A.N. , Kettmann R. , Burny A.
      Biochim. Biophys. Acta1087:339-340(1990) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 1-17
      strain: Belgian Landrace.
    5. 5.
      "A partial cDNA clone for porcine glucosephosphate isomerase: isolation, characterization and use in detection of restriction fragment length polymorphisms."
      Davies W. , Harbitz I. , Hauge J.G.
      Anim. Genet.18:233-240(1987) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 238-357
    6. 6.
      "Three-dimensional structure of pig muscle phosphoglucose isomerase at 6-A resolution."
      Muirhead H. , Shaw P.J.
      J. Mol. Biol.89:195-203(1974) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (6.0 ANGSTROMS)
    7. 7.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.6 ANGSTROMS);PROTEIN SEQUENCE OF 554-558
    8. 8.
      "Crystal structure of phosphoglucose isomerase from pig muscle and its complex with 5-phosphoarabinonate."
      Davies C. , Muirhead H.
      Proteins49:577-579(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.5 ANGSTROMS) ALONE AND IN COMPLEX WITH 5-PHOSPHOARABINONATE
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