Protein name:
Granzyme A ;
Alternative:
Organism:
Bovine (Bos taurus).
General Annotation
Sub Unit:
Interacts with APEX1 (By similarity). Homodimer; disulfide-linked.
Function:
This enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Lys or Arg. Cleaves after 'Lys-31' APEX1 and destroys its oxidative repair activity. Involved in apoptosis.
Subcellular Location:
Secreted
Cytoplasmic granule
Cytoplasmic granules of cytolytic T-lymphocytes.
Protein Attributes:
50:
MNIPFPFSFP | PAICLLLIPG | VFPVSCEGII | GGNEVAPHTR | RYMALIKGLK |
100:
LCAGALIKEN | WVLTAAHCDL | KGNPQVILGA | HSTSHKEKLD | QVFSIKKAIP |
150:
YPCFDPQTFE | GDLQLLQLEG | KATMTKAVGI | LQLPRTEDDV | KPHTKCHVAG |
200:
WGSTKKDACQ | MSNALREANV | TVIDRKICND | AQHYNFNPVI | DLSMICAGGR |
250:
KGEDDSCEGD | SGSPLICDNV | FRGVTSFGKC | GNPQKPGIYI | LLTKKHLNWI |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Bovine
Mouse
ELISA Kit for Bovine Granzyme A
ELISA Kit for Bovine Granzyme A
ELISA Kit for Bovine Granzyme A
CLIA Kit for Bovine Granzyme A
CLIA Kit for Bovine Granzyme A
CLIA Kit for Bovine Granzyme A
Polyclonal Antibody for Bovine Granzyme A
Polyclonal Antibody for Bovine Granzyme A
Polyclonal Antibody for Bovine Granzyme A
Monoclonal Antibody for Bovine Granzyme A
Monoclonal Antibody for Bovine Granzyme A
Monoclonal Antibody for Bovine Granzyme A
Protein for Bovine Granzyme A
Protein for Bovine Granzyme A
Protein for Bovine Granzyme A
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
Jenne D.E.
Submitted (2003-02) to the EMBL/GenBank/DDBJ databases
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Cited for : NUCLEOTIDE SEQUENCE [MRNA]