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Index > Protein center > Gzma(Gene name) > Mouse
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  • Gzma (Gene name),
  • Granzyme A (Protein name ),  GRAA_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Gzma(Ctla-3;Ctla3;Mtsp-1);
    Protein name:
    Granzyme A;
    Alternative:
    CTLA-3;Autocrine thymic lymphoma granzyme-like serine protease;T cell-specific serine protease 1(TSP-1);Fragmentin-1;
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Interacts with APEX1 (By similarity). Homodimer; disulfide-linked.
    Function:
    This enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Lys or Arg. Cleaves APEX1 after 'Lys-30' and destroys its oxidative repair activity. Involved in apoptosis.
    Subcellular Location:
    Secreted Cytoplasmic granule Cytoplasmic granules of cytolytic T-lymphocytes.
    Protein Attributes:
    Sequence length:
    260
    Sequence:
    50:
    MRNASGPRGP | SLATLLFLLL | IPEGGCERII | GGDTVVPHSR | PYMALLKLSS | 
    100:
    NTICAGALIE | KNWVLTAAHC | NVGKRSKFIL | GAHSINKEPE | QQILTVKKAF | 
    150:
    PYPCYDEYTR | EGDLQLVRLK | KKATVNRNVA | ILHLPKKGDD | VKPGTRCRVA | 
    200:
    GWGRFGNKSA | PSETLREVNI | TVIDRKICND | EKHYNFHPVI | GLNMICAGDL | 
    250:
    RGGKDSCNGD | SGSPLLCDGI | LRGITSFGGE | KCGDRRWPGV | YTFLSDKHLN | 
    260:
    WIKKIMKGSV | 
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    String:
    SMR:
    Pfam:
    KEGG:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse Granzyme A
    Cat.:
    E0599h
    Price:
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    MSDS:
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    Packing:
    96T
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    ELISA Kit for Mouse Granzyme A
    Cat.:
    E0599b
    Price:
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    MSDS:
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    Packing:
    96T
    Range:
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    ELISA Kit for Mouse Granzyme A
    Cat.:
    E0599m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Mouse Granzyme A
    Cat.:
    U0599h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Granzyme A
    Cat.:
    U0599b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Granzyme A
    Cat.:
    U0599m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Mouse Granzyme A
    Cat.:
    P0599Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse Granzyme A
    Polyclonal Antibody for Mouse Granzyme A
    Cat.:
    P0599Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Mouse Granzyme A
    Monoclonal Antibody for Mouse Granzyme A
    Monoclonal Antibody for Mouse Granzyme A
    Protein for Mouse Granzyme A
    Protein for Mouse Granzyme A
    Protein for Mouse Granzyme A

    R&D Technical Data
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    Precision
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Recovery
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Linearity
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    References
    1. 1.
      "cDNA clones from autocrine thymic lymphoma cells encode two mitogenic proteins, a serine protease and a truncated T-cell receptor beta-chain."
      Bogenberger J. , Haas M.
      Oncogene Res.3:301-312(1988) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      strain: C57BL/6.
    2. 2.
      "Organization of the gene encoding the mouse T-cell-specific serine proteinase 'granzyme A'."
      Ebnet K. , Kramer M.D. , Simon M.M.
      Genomics13:502-508(1992) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
      strain: C57BL/6.
    3. 3.
      "Genomic organization of the mouse granzyme A gene. Two mRNAs encode the same mature granzyme A with different leader peptides."
      Hershberger R.J. , Gershenfeld H.K. , Weissman I.L. , Su L.
      J. Biol. Chem.267:25488-25493(1992) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] (ISOFORMS HF1 AND HF2)
    4. 4.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM HF1)
    5. 5.
      "Granzymes, a family of serine proteases released from granules of cytolytic T lymphocytes upon T cell receptor stimulation."
      Jenne D.E. , Tschopp J.
      Immunol. Rev.103:53-71(1988) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 1-37
    6. 6.
      "Cloning of a cDNA for a T cell-specific serine protease from a cytotoxic T lymphocyte."
      Gershenfeld H.K. , Weissman I.L.
      Science232:854-858(1986) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 12-260
    7. 7.
      "A family of serine esterases in lytic granules of cytolytic T lymphocytes."
      Masson D. , Tschopp J.
      Cell49:679-685(1987) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 29-48
    8. 8.
      "Identification of granzyme A isolated from cytotoxic T-lymphocyte-granules as one of the proteases encoded by CTL-specific genes."
      Masson D. , Zamai M. , Tschopp J.
      FEBS Lett.208:84-88(1986) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 29-53
    9. 9.
      "Induction of T cell serine proteinase 1 (TSP-1)-specific mRNA in mouse T lymphocytes."
      Simon H.G. , Fruth U. , Eckerskorn C. , Lottspeich F. , Kramer M.D. , Nerz G. , Simon M.M.
      Eur. J. Immunol.18:855-861(1988) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 29-46
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