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Index > Protein center > Hspa9(Gene name) > Mouse
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  • Hspa9 (Gene name),
  • Stress-70 protein, mitochondrial (Protein name ),  GRP75_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Hspa9(Grp75;Hsp74;Hspa9a);
    Protein name:
    Stress-70 protein, mitochondrial;
    Alternative:
    Heat shock 70 kDa protein 9;75 kDa glucose-regulated protein(GRP-75);Peptide-binding protein 74(PBP74);Mortalin;p66 MOT;
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Interacts with FXN. Interacts with HSCB.
    Function:
    Implicated in the control of cell proliferation and cellular aging. May also act as a chaperone.
    Subcellular Location:
    Mitochondrion
    Protein Attributes:
    Sequence length:
    679
    Sequence:
    50:
    MISASRAAAA | RLVGTAASRS | PAAARPQDGW | NGLSHEAFRF | VSRRDYASEA | 
    100:
    IKGAVVGIDL | GTTNSCVAVM | EGKQAKVLEN | AEGARTTPSV | VAFTADGERL | 
    150:
    VGMPAKRQAV | TNPNNTFYAT | KRLIGRRYDD | PEVQKDTKNV | PFKIVRASNG | 
    200:
    DAWVEAHGKL | YSPSQIGAFV | LMKMKETAEN | YLGHTAKNAV | ITVPAYFNDS | 
    250:
    QRQATKDAGQ | ISGLNVLRVI | NEPTAAALAY | GLDKSEDKVI | AVYDLGGGTF | 
    300:
    DISILEIQKG | VFEVKSTNGD | TFLGGEDFDQ | ALLRHIVKEF | KRETGVDLTK | 
    350:
    DNMALQRVRE | AAEKAKCELS | SSVQTDINLP | YLTMDASGPK | HLNMKLTRAQ | 
    400:
    FEGIVTDLIK | RTIAPCQKAM | QDAEVSKSDI | GEVILVGGMT | RMPKVQQTVQ | 
    450:
    DLFGRAPSKA | VNPDEAVAIG | AAIQGGVLAG | DVTDVLLLDV | TPLSLGIETL | 
    500:
    GGVFTKLINR | NTTIPTKKSQ | VFSTAADGQT | QVEIKVCQGE | REMAGDNKLL | 
    550:
    GQFTLIGIPP | APRGVPQIEV | TFDIDANGIV | HVSAKDKGTG | REQQIVIQSS | 
    600:
    GGLSKDDIEN | MVKNAEKYAE | EDRRKKERVE | AVNMAEGIIH | DTETKMEEFK | 
    650:
    DQLPADECNK | LKEEISKVRA | LLARKDSETG | ENIRQAASSL | QQASLKLFEM | 
    679:
    AYKKMASERE | GSGSSGTGEQ | KEDQKEEKQ
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    KEGG:
    Pfam:
    UniGene:
    SMR:
    String:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse Stress-70 protein, mitochondrial
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    E9060h
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    ELISA Kit for Mouse Stress-70 protein, mitochondrial
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    E9060m
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    ELISA Kit for Mouse Stress-70 protein, mitochondrial
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    E9060d
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    ELISA Kit for Mouse Stress-70 protein, mitochondrial
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    E9060b
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    ELISA Kit for Mouse Stress-70 protein, mitochondrial
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    E9060c
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    ELISA Kit for Mouse Stress-70 protein, mitochondrial
    Cat.:
    E9060r
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    Packing:
    96T
    CLIA Kit for Mouse Stress-70 protein, mitochondrial
    Cat.:
    U9060d
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    96T
    CLIA Kit for Mouse Stress-70 protein, mitochondrial
    Cat.:
    U9060b
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    96T
    CLIA Kit for Mouse Stress-70 protein, mitochondrial
    Cat.:
    U9060c
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    Packing:
    96T
    CLIA Kit for Mouse Stress-70 protein, mitochondrial
    Cat.:
    U9060r
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Mouse Stress-70 protein, mitochondrial
    Cat.:
    U9060h
    Price:
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Mouse Stress-70 protein, mitochondrial
    Cat.:
    U9060m
    Price:
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    MSDS:
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    Packing:
    96T
    Polyclonal Antibody for Mouse Stress-70 protein, mitochondrial
    Polyclonal Antibody for Mouse Stress-70 protein, mitochondrial
    Cat.:
    P9060Rb-h
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse Stress-70 protein, mitochondrial
    Cat.:
    P9060Rb-m
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse Stress-70 protein, mitochondrial
    Cat.:
    P9060Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse Stress-70 protein, mitochondrial
    Polyclonal Antibody for Mouse Stress-70 protein, mitochondrial
    Monoclonal Antibody for Mouse Stress-70 protein, mitochondrial
    Monoclonal Antibody for Mouse Stress-70 protein, mitochondrial
    Monoclonal Antibody for Mouse Stress-70 protein, mitochondrial
    Monoclonal Antibody for Mouse Stress-70 protein, mitochondrial
    Monoclonal Antibody for Mouse Stress-70 protein, mitochondrial
    Monoclonal Antibody for Mouse Stress-70 protein, mitochondrial
    Protein for Mouse Stress-70 protein, mitochondrial
    Protein for Mouse Stress-70 protein, mitochondrial
    Protein for Mouse Stress-70 protein, mitochondrial
    Protein for Mouse Stress-70 protein, mitochondrial
    Protein for Mouse Stress-70 protein, mitochondrial
    Protein for Mouse Stress-70 protein, mitochondrial

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    Linearity
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    References
    1. 1.
      "Identification of a novel member of mouse hsp70 family. Its association with cellular mortal phenotype."
      Wadhwa R. , Kaul S.C. , Ikawa Y. , Sugimoto Y.
      J. Biol. Chem.268:6615-6621(1993) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      strain: CD-1-ICR.
      tissue: Embryonic fibroblast.
    2. 2.
      Wadhwa R.
      Submitted (1999-08) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SEQUENCE REVISION TO 123
    3. 3.
      "Induction of cellular senescence by transfection of cytosolic mortalin cDNA in NIH 3T3 cells."
      Wadhwa R. , Kaul S.C. , Sugimoto Y. , Mitsui Y.
      J. Biol. Chem.268:22239-22242(1993) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE
      strain: CD-1-ICR.
      tissue: Embryonic fibroblast.
    4. 4.
      "Cloning of the gene encoding peptide-binding protein 74 shows that it is a new member of the heat shock protein 70 family."
      Domanico S.Z. , Denagel D.C. , Dahlseid J.N. , Green J.M. , Pierce S.K.
      Mol. Cell. Biol.13:3598-3610(1993) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];PARTIAL PROTEIN SEQUENCE
      tissue: B-cell.
    5. 5.
      "Structure and organization of the gene encoding a mouse mitochondrial stress-70 protein."
      Michikawa Y. , Baba T. , Arai Y. , Sakakura T. , Kusakabe M.
      FEBS Lett.336:27-33(1993) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
      strain: BALB/c.
      tissue: Liver.
    6. 6.
      "Antigenic protein specific for C3H strain mouse is a mitochondrial stress-70 protein."
      Michikawa Y. , Baba T. , Arai Y. , Sakakura T. , Tanaka M. , Kusakabe M.
      Biochem. Biophys. Res. Commun.196:223-232(1993) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      strain: C3H/HeN.
      tissue: Kidney.
    7. 7.
      "The transcriptional landscape of the mammalian genome."
      Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
      Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: C57BL/6J.
      strain: DBA/2.
      tissue: Embryo.
      tissue: Kidney.
      tissue: Liver.
    8. 8.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
      strain: C57BL/6J.
    9. 9.
      Mural R.J. , Adams M.D. , Myers E.W. , Smith H.O. , Venter J.C.
      Submitted (2005-07) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    10. 10.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: C57BL/6.
      tissue: Brain.
    11. 11.
      "Separation and sequencing of familiar and novel murine proteins using preparative two-dimensional gel electrophoresis."
      Merrick B.A. , Patterson R.M. , Wichter L.L. , He C. , Selkirk J.K.
      Electrophoresis15:735-745(1994) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 47-70
      tissue: Fibroblast.
    12. 12.
      Lubec G. , Klug S. , Yang J.W. , Zigmond M.
      Submitted (2007-07) to the UniProtKB
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 188-202; 266-284; 349-360; 395-405 AND 499-513;IDENTIFICATION BY MASS SPECTROMETRY
      tissue: Brain.
      tissue: Hippocampus.
    13. 13.
      "PBP74, a new member of the mammalian 70-kDa heat shock protein family, is a mitochondrial protein."
      Dahlseid J.N. , Lill R. , Green J.M. , Xu X. , Qiu Y. , Pierce S.K.
      Mol. Biol. Cell5:1265-1275(1994) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION
    14. 14.
      "SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways."
      Park J. , Chen Y. , Tishkoff D.X. , Peng C. , Tan M. , Dai L. , Xie Z. , Zhang Y. , Zwaans B.M. , Skinner M.E. , Lombard D.B. , Zhao Y.
      Mol. Cell50:919-930(2013) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-135; LYS-300; LYS-360 AND LYS-567;SUCCINYLATION [LARGE SCALE ANALYSIS] AT LYS-135; LYS-138; LYS-206; LYS-300; LYS-360; LYS-368; LYS-394; LYS-567; LYS-600; LYS-610 AND LYS-646;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Embryonic fibroblast.
      tissue: Liver.
    15. 15.
      "Label-free quantitative proteomics of the lysine acetylome in mitochondria identifies substrates of SIRT3 in metabolic pathways."
      Rardin M.J. , Newman J.C. , Held J.M. , Cusack M.P. , Sorensen D.J. , Li B. , Schilling B. , Mooney S.D. , Kahn C.R. , Verdin E. , Gibson B.W.
      Proc. Natl. Acad. Sci. U.S.A.110:6601-6606(2013) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-76; LYS-135; LYS-138; LYS-206; LYS-234; LYS-288; LYS-300; LYS-360; LYS-567; LYS-600; LYS-612 AND LYS-646;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Liver.
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