HGF ELISA Kit for Human(Homo sapiens) | EIAab.comHGF ELISA Kit for Human(Homo sapiens)

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Index > Protein center > HGF(Gene name) > Human

HGF (Gene name),

Hepatocyte growth factor (Protein name ), HGF_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

HGF(HPTA);

Protein name:

Hepatocyte growth factor;

Alternative:

Scatter factor(SF);Hepatopoietin-A;

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Dimer of an alpha chain and a beta chain linked by a disulfide bond.

Function:

HGF is a potent mitogen for mature parenchymal hepatocyte cells, seems to be an hepatotrophic factor, and acts as growth factor for a broad spectrum of tissues and cell types. It has no detectable protease activity.

Subcellular Location:

N/A

Protein Attributes:

Sequence length:

728

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

500:

550:

600:

650:

700:

728:

NRPGIFVRVA | YYAKWIHKII | LTYKVPQS

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

UniGene:

Hs.396530

String:

P14210

KEGG:

hsa:3082

SMR:

P14210

MIM:

142409

Pfam:

PF00051

Uniprot:

P14210

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ELISA Kit for Human Hepatocyte growth factor

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E0047h

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96T

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ELISA Kit for Human Hepatocyte growth factor

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E0047r

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96T

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ELISA Kit for Human Hepatocyte growth factor

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E0047m

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ELISA Kit for Human Hepatocyte growth factor

Cat.:

E0047b

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96T

ELISA Kit for Human Hepatocyte growth factor

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E0047d

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CLIA Kit for Human Hepatocyte growth factor

Cat.:

U0047d

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96T

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CLIA Kit for Human Hepatocyte growth factor

Cat.:

U0047r

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96T

CLIA Kit for Human Hepatocyte growth factor

Cat.:

U0047m

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96T

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CLIA Kit for Human Hepatocyte growth factor

Cat.:

U0047h

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96T

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CLIA Kit for Human Hepatocyte growth factor

Cat.:

U0047b

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96T

Polyclonal Antibody for Human Hepatocyte growth factor

Cat.:

P0047Rb-r

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Packing:

40ug/0.2ml

Polyclonal Antibody for Human Hepatocyte growth factor

Cat.:

P0047Rb-h

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40ug/0.2ml

Polyclonal Antibody for Human Hepatocyte growth factor

Cat.:

P0047Rb-m

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40ug/0.2ml

Polyclonal Antibody for Human Hepatocyte growth factor

Monoclonal Antibody for Human Hepatocyte growth factor

Protein for Human Hepatocyte growth factor

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

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Linearity

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References

1.

"Molecular cloning and sequence analysis of cDNA for human hepatocyte growth factor."
Miyazawa K. , Tsubouchi H. , Naka D. , Takahashi K. , Okigaki M. , Arakaki N. , Nakayama H. , Hirono S. , Sakiyama O. , Takahashi K. , Gohda E. , Daikuhara Y. , Kitamura N.
Biochem. Biophys. Res. Commun.163:967-973(1989) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
tissue: Placenta.
2.

"Molecular cloning and expression of human hepatocyte growth factor."
Nakamura T. , Nishizawa T. , Hagiya M. , Seki T. , Shimonishi M. , Sugimura A. , Tashiro K. , Shimizu S.
Nature342:440-443(1989) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);PROTEIN SEQUENCE OF 55-73 AND 495-520
tissue: Liver.
3.

"Isolation and expression of cDNA for different forms of hepatocyte growth factor from human leukocyte."
Seki T. , Ihara I. , Sugimura A. , Shimonishi M. , Nishizawa T. , Asami O. , Hagiya M. , Nakamura T. , Shimizu S.
Biochem. Biophys. Res. Commun.172:321-327(1990) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
tissue: Leukocyte.
4.

"Organization of the human hepatocyte growth factor-encoding gene."
Seki T. , Hagiya M. , Shimonishi M. , Nakamura T. , Shimizu S.
Gene102:213-219(1991) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] (ISOFORM 1)
5.

"An alternatively processed mRNA generated from human hepatocyte growth factor gene."
Miyazawa K. , Kitamura A. , Naka D. , Kitamura N.
Eur. J. Biochem.197:15-22(1991) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2)
tissue: Placenta.
6.

"A broad-spectrum human lung fibroblast-derived mitogen is a variant of hepatocyte growth factor."
Rubin J.S. , Chan A.M.-L. , Bottaro D.P. , Burgess W.H. , Taylor W.G. , Cech A.C. , Hirschfield D.W. , Wong J. , Miki T. , Finch P.W. , Aaronson S.A.
Proc. Natl. Acad. Sci. U.S.A.88:415-419(1991) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 3);PROTEIN SEQUENCE OF 583-592
tissue: Lung fibroblast.
7.

"Evidence for the identity of human scatter factor and human hepatocyte growth factor."
Weidner K.M. , Arakaki N. , Hartmann G. , Vandekerckhove J. , Weingart S. , Rieder H. , Fonatsch C. , Tsubouchi H. , Hishida T. , Daikuhara Y. , Birchmeier W.
Proc. Natl. Acad. Sci. U.S.A.88:7001-7005(1991) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
tissue: Embryonic fibroblast.
8.

"Identification of a competitive HGF antagonist encoded by an alternative transcript."
Chan A.M.-L. , Rubin J.S. , Bottaro D.P. , Hirschfield D.W. , Chedid M. , Aaronson S.A.
Science254:1382-1385(1991) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 4)
9.

"A functional domain in the heavy chain of scatter factor/hepatocyte growth factor binds the c-Met receptor and induces cell dissociation but not mitogenesis."
Hartmann G. , Naldini L. , Weidner K.M. , Sachs M. , Vigna E. , Comoglio P.M. , Birchmeier W.
Proc. Natl. Acad. Sci. U.S.A.89:11574-11578(1992) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2);MUTAGENESIS OF ARG-494
10.

"Hepatocyte growth factor (HGF)/NK1 is a naturally occurring HGF/scatter factor variant with partial agonist/antagonist activity."
Cioce V. , Csaky K.G. , Chan A.M.-L. , Bottaro D.P. , Taylor W.G. , Jensen R. , Aaronson S.A. , Rubin J.S.
J. Biol. Chem.271:13110-13115(1996) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 6)
11.

NIEHS SNPs program
Submitted (2003-02) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];VARIANTS LYS-304 AND TYR-330
12.

"The DNA sequence of human chromosome 7."
Hillier L.W. , Fulton R.S. , Fulton L.A. , Graves T.A. , Pepin K.H. , Wagner-McPherson C. , Layman D. , Maas J. , Jaeger S. , Walker R. , Wylie K. , Sekhon M. , Becker M.C. , O'Laughlin M.D. , Schaller M.E. , Fewell G.A. , Delehaunty K.D. , Miner T.L. , more...
Nature424:157-164(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
13.

"Human chromosome 7: DNA sequence and biology."
Scherer S.W. , Cheung J. , MacDonald J.R. , Osborne L.R. , Nakabayashi K. , Herbrick J.-A. , Carson A.R. , Parker-Katiraee L. , Skaug J. , Khaja R. , Zhang J. , Hudek A.K. , Li M. , Haddad M. , Duggan G.E. , Fernandez B.A. , Kanematsu E. , Gentles S. , more...
Science300:767-772(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
14.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1; 5 AND 6)
tissue: Brain.
15.

"Structural organization and the transcription initiation site of the human hepatocyte growth factor gene."
Miyazawa K. , Kitamura A. , Kitamura N.
Biochemistry30:9170-9176(1991) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE OF 1-208 AND 249-695 (ISOFORM 1)
16.

"Identification of the N-terminal residue of the heavy chain of both native and recombinant human hepatocyte growth factor."
Yoshiyama Y. , Arakaki N. , Naka D. , Takahashi K. , Hirono S. , Kondo J. , Nakayama H. , Gohda E. , Kitamura N. , Tsubouchi H. , Ishii T. , Hishida T. , Daikuhara Y.
Biochem. Biophys. Res. Commun.175:660-667(1991) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SIGNAL SEQUENCE CLEAVAGE SITE;PYROGLUTAMATE FORMATION AT GLN-32
17.

"Hepatocyte growth factor is linked by O-glycosylated oligosaccharide on the alpha chain."
Shimizu N. , Hara H. , Sogabe T. , Sakai H. , Ihara I. , Inoue H. , Nakamura T. , Shimizu S.
Biochem. Biophys. Res. Commun.189:1329-1335(1992) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION AT THR-476
18.

"Structure-function analysis of hepatocyte growth factor: identification of variants that lack mitogenic activity yet retain high affinity receptor binding."
Lokker N.A. , Mark M.R. , Luis E.A. , Bennett G.L. , Robbins K.A. , Baker J.B. , Godowski P.J.
EMBO J.11:2503-2510(1992) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: MUTAGENESIS
19.

"Noncoding mutations of HGF are associated with nonsyndromic hearing loss, DFNB39."
Schultz J.M. , Khan S.N. , Ahmed Z.M. , Riazuddin S. , Waryah A.M. , Chhatre D. , Starost M.F. , Ploplis B. , Buckley S. , Velasquez D. , Kabra M. , Lee K. , Hassan M.J. , Ali G. , Ansar M. , Ghosh M. , Wilcox E.R. , Ahmad W. , more...
Am. J. Hum. Genet.85:25-39(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INVOLVEMENT IN DFNB39
20.

"SRPX2 is a novel chondroitin sulfate proteoglycan that is overexpressed in gastrointestinal cancer."
Tanaka K. , Arao T. , Tamura D. , Aomatsu K. , Furuta K. , Matsumoto K. , Kaneda H. , Kudo K. , Fujita Y. , Kimura H. , Yanagihara K. , Yamada Y. , Okamoto I. , Nakagawa K. , Nishio K.
PLoS ONE7:E27922-E27922(2012) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH SRPX2
21.

"The solution structure of the N-terminal domain of hepatocyte growth factor reveals a potential heparin-binding site."
Zhou H. , Mazzulla M.J. , Kaufman J.D. , Stahl S.J. , Wingfield P.T. , Rubin J.S. , Bottaro D.P. , Byrd R.A.
Structure6:109-116(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR OF 31-127
22.

"Crystal structure of the NK1 fragment of human hepatocyte growth factor at 2.0-A resolution."
Ultsch M. , Lokker N.A. , Godowski P.J. , de Vos A.M.
Structure6:1383-1393(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.0 ANGSTROMS) OF 35-210
23.

"Crystal structure of the HGF beta-chain in complex with the Sema domain of the Met receptor."
Stamos J. , Lazarus R.A. , Yao X. , Kirchhofer D. , Wiesmann C.
EMBO J.23:2325-2335(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (3.22 ANGSTROMS) OF 495-728 IN COMPLEX WITH MET;FUNCTION;SUBUNIT;DISULFIDE BONDS
24.

"Structural basis for agonism and antagonism of hepatocyte growth factor."
Tolbert W.D. , Daugherty-Holtrop J. , Gherardi E. , Vande Woude G. , Xu H.E.
Proc. Natl. Acad. Sci. U.S.A.107:13264-13269(2010) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.6 ANGSTROMS) OF 28-289;DISULFIDE BONDS;FUNCTION

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