LAMB2 ELISA Kit for Human(Homo sapiens) | EIAab.comLAMB2 ELISA Kit for Human(Homo sapiens)

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LAMB2 (Gene name),

Laminin subunit beta-2 (Protein name ), LAMB2_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

LAMB2(LAMS);

Protein name:

Laminin subunit beta-2;

Alternative:

Laminin-11 subunit beta;Laminin B1s chain;Laminin-15 subunit beta;Laminin-14 subunit beta;Laminin-4 subunit beta;Laminin-3 subunit beta;Laminin-9 subunit beta;Laminin-7 subunit beta;S-laminin subunit beta(S-LAM beta);

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Laminin is a complex glycoprotein, consisting of three different polypeptide chains (alpha, beta, gamma), which are bound to each other by disulfide bonds into a cross-shaped molecule comprising one long and three short arms with globules at each end. Beta-2 is a subunit of laminin-3 (laminin-121 or S-laminin), laminin-4 (laminin-221 or S-merosin), laminin-7 (laminin-321 or KS-laminin), laminin-9 (laminin-421), laminin-11 (laminin-521), laminin-14 (laminin-423) and laminin-15 (laminin-523).

Function:

Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components.

Subcellular Location:

Secreted extracellular space extracellular matrix basement membrane S-laminin is concentrated in the synaptic cleft of the neuromuscular junction.

Protein Attributes:

Sequence length:

1798

Sequence:

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1798:

RLQELEGTYE | ENERALESKA | AQLDGLEARM | RSVLQAINLQ | VQIYNTCQ

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

KEGG:

hsa:3913

UniGene:

Hs.439726

SMR:

P55268

String:

P55268

MIM:

150325

STRING:

9606.ENSP00000307156

Pfam:

PF00053

Uniprot:

P55268

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ELISA Kit for Human Laminin subunit beta-2

Cat.:

E1472h

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Manual:

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MSDS:

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Packing:

96T

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ELISA Kit for Human Laminin subunit beta-2

Cat.:

E1472r

Price:

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MSDS:

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Packing:

96T

ELISA Kit for Human Laminin subunit beta-2

Cat.:

E1472m

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Packing:

96T

CLIA Kit for Human Laminin subunit beta-2

Cat.:

U1472h

Price:

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MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Human Laminin subunit beta-2

Cat.:

U1472m

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Human Laminin subunit beta-2

Cat.:

U1472r

Price:

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MSDS:

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Packing:

96T

Polyclonal Antibody for Human Laminin subunit beta-2

Cat.:

P1472Rb-m

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Packing:

40ug/0.2ml

Polyclonal Antibody for Human Laminin subunit beta-2

Cat.:

P1472Rb-h

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Packing:

40ug/0.2ml

Polyclonal Antibody for Human Laminin subunit beta-2

Cat.:

P1472Rb-r

Price:

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Packing:

40ug/0.2ml

Monoclonal Antibody for Human Laminin subunit beta-2

Protein for Human Laminin subunit beta-2

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Human beta 2 chain of laminin (formerly S chain): cDNA cloning, chromosomal localization, and expression in carcinomas."
Wewer U.M. , Gerecke D.R. , Durkin M.E. , Kurtz K.S. , Mattei M.-G. , Champliaud M.-F. , Burgeson R.E. , Albrechtsen R.
Genomics24:243-252(1994) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA]
2.

"The human laminin beta 2 chain (S-laminin): structure, expression in fetal tissues and chromosomal assignment of the LAMB2 gene."
Iivanainen A. , Vuolteenaho R. , Sainio K. , Eddy R. , Shows T.B. , Sariola H. , Tryggvason K.
Matrix Biol.14:489-497(1995) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
3.

"Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry."
Chen R. , Jiang X. , Sun D. , Han G. , Wang F. , Ye M. , Wang L. , Zou H.
J. Proteome Res.8:651-661(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-1308; ASN-1348 AND ASN-1499
tissue: Liver.
4.

"Initial characterization of the human central proteome."
Burkard T.R. , Planyavsky M. , Kaupe I. , Breitwieser F.P. , Buerckstuemmer T. , Bennett K.L. , Superti-Furga G. , Colinge J.
BMC Syst. Biol.5:17-17(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
5.

"Human laminin beta2 deficiency causes congenital nephrosis with mesangial sclerosis and distinct eye abnormalities."
Zenker M. , Aigner T. , Wendler O. , Tralau T. , Muentefering H. , Fenski R. , Pitz S. , Schumacher V. , Royer-Pokora B. , Wuehl E. , Cochat P. , Bouvier R. , Kraus C. , Mark K. , Madlon H. , Doetsch J. , Rascher W. , Maruniak-Chudek I. , more...
Hum. Mol. Genet.13:2625-2632(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT PIERSS TRP-246
6.

"Recessive missense mutations in LAMB2 expand the clinical spectrum of LAMB2-associated disorders."
Hasselbacher K. , Wiggins R.C. , Matejas V. , Hinkes B.G. , Mucha B. , Hoskins B.E. , Ozaltin F. , Nuernberg G. , Becker C. , Hangan D. , Pohl M. , Kuwertz-Broeking E. , Griebel M. , Schumacher V. , Royer-Pokora B. , Bakkaloglu A. , Nuernberg P. , Zenker M. , more...
Kidney Int.70:1008-1012(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS PIERSS GLN-246; ARG-321; LYS-1380 AND PHE-1393
7.

"A novel mutation of LAMB2 in a multigenerational mennonite family reveals a new phenotypic variant of Pierson syndrome."
Mohney B.G. , Pulido J.S. , Lindor N.M. , Hogan M.C. , Consugar M.B. , Peters J. , Pankratz V.S. , Nasr S.H. , Smith S.J. , Gloor J. , Kubly V. , Spencer D. , Nielson R. , Puffenberger E.G. , Strauss K.A. , Morton D.H. , Eldahdah L. , Harris P.C.
Ophthalmology118:1137-1144(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT NPHS5 ARG-147

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