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Index > Protein center > LILRA3(Gene name) > Human
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  • LILRA3 (Gene name),
  • Leukocyte immunoglobulin-like receptor subfamily A member 3 (Protein name ),  LIRA3_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    LILRA3(ILT6;LIR4);
    Protein name:
    Leukocyte immunoglobulin-like receptor subfamily A member 3;
    Alternative:
    Immunoglobulin-like transcript 6(ILT-6);CD85 antigen-like family member E;Monocyte inhibitory receptor HM43/HM31;Leukocyte immunoglobulin-like receptor 4(LIR-4);
    CD:
    CD85e;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    May act as soluble receptor for class I MHC antigens.
    Subcellular Location:
    Secreted
    Protein Attributes:
    Sequence length:
    439
    Sequence:
    50:
    MTPILTVLIC | LGLSLDPRTH | VQAGPLPKPT | LWAEPGSVIT | QGSPVTLRCQ | 
    100:
    GSLETQEYHL | YREKKTALWI | TRIPQELVKK | GQFPILSITW | EHAGRYCCIY | 
    150:
    GSHTAGLSES | SDPLELVVTG | AYSKPTLSAL | PSPVVTSGGN | VTIQCDSQVA | 
    200:
    FDGFILCKEG | EDEHPQCLNS | HSHARGSSRA | IFSVGPVSPS | RRWSYRCYGY | 
    250:
    DSRAPYVWSL | PSDLLGLLVP | GVSKKPSLSV | QPGPVVAPGE | KLTFQCGSDA | 
    300:
    GYDRFVLYKE | WGRDFLQRPG | RQPQAGLSQA | NFTLGPVSRS | YGGQYTCSGA | 
    350:
    YNLSSEWSAP | SDPLDILITG | QIRARPFLSV | RPGPTVASGE | NVTLLCQSQG | 
    400:
    GMHTFLLTKE | GAADSPLRLK | SKRQSHKYQA | EFPMSPVTSA | HAGTYRCYGS | 
    439:
    LSSNPYLLTH | PSDPLELVVS | GAAETLSPPQ | NKSDSKAGE
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    String:
    MIM:
    KEGG:
    UniGene:
    SMR:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Human Leukocyte immunoglobulin-like receptor subfamily A member 3
    Cat.:
    E15366h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Leukocyte immunoglobulin-like receptor subfamily A member 3
    Cat.:
    U15366h
    Price:
    Please sign in first.
    MSDS:
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    Packing:
    96T
    Polyclonal Antibody for Human Leukocyte immunoglobulin-like receptor subfamily A member 3
    Cat.:
    P15366Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human Leukocyte immunoglobulin-like receptor subfamily A member 3
    Protein for Human Leukocyte immunoglobulin-like receptor subfamily A member 3

    R&D Technical Data
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    Precision
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Recovery
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Linearity
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    References
    1. 1.
      "Molecular identification of a novel family of human Ig superfamily members that possess immunoreceptor tyrosine-based inhibition motifs and homology to the mouse gp49B1 inhibitory receptor."
      Arm J.P. , Nwankwo C. , Austen K.F.
      J. Immunol.159:2342-2349(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);VARIANT SER-3;TISSUE SPECIFICITY
      tissue: Lung.
      tissue: Monocyte.
    2. 2.
      "A family of human lymphoid and myeloid Ig-like receptors, some of which bind to MHC class I molecules."
      Borges L. , Hsu M.-L. , Fanger N. , Kubin M. , Cosman D.
      J. Immunol.159:5192-5196(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);VARIANT SER-3;TISSUE SPECIFICITY
    3. 3.
      "Cloning of novel immunoglobulin superfamily receptors expressed on human myeloid and lymphoid cells: structural evidence for new stimulatory and inhibitory pathways."
      Samaridis J. , Colonna M.
      Eur. J. Immunol.27:660-665(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2)
    4. 4.
      "The DNA sequence and biology of human chromosome 19."
      Grimwood J. , Gordon L.A. , Olsen A.S. , Terry A. , Schmutz J. , Lamerdin J.E. , Hellsten U. , Goodstein D. , Couronne O. , Tran-Gyamfi M. , Aerts A. , Altherr M. , Ashworth L. , Bajorek E. , Black S. , Branscomb E. , Caenepeel S. , Carrano A.V. , more...
      Nature428:529-535(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    5. 5.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA];VARIANT SER-3
      tissue: Peripheral blood leukocyte.
    6. 6.
      "DNA sequence variation and molecular genotyping of natural killer leukocyte immunoglobulin-like receptor, LILRA3."
      Norman P.J. , Carey B.S. , Stephens H.A. , Vaughan R.W.
      Immunogenetics55:165-171(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-420;VARIANTS ARG-107 AND HIS-301
    7. 7.
      "Signal peptide prediction based on analysis of experimentally verified cleavage sites."
      Zhang Z. , Henzel W.J.
      Protein Sci.13:2819-2824(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 24-38
    8. 8.
      "Glycosylation in a mammalian expression system is critical for the production of functionally active leukocyte immunoglobulin-like receptor A3 protein."
      Lee T.H. , Mitchell A. , Liu Lau S. , An H. , Rajeaskariah P. , Wasinger V. , Raftery M. , Bryant K. , Tedla N.
      J. Biol. Chem.288:32873-32885(2013) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION AT ASN-140; ASN-281; ASN-302; ASN-341 AND ASN-431;FUNCTION
    9. 9.
      "LILRA3 binds both classical and non-classical HLA class I molecules but with reduced affinities compared to LILRB1/LILRB2: structural evidence."
      Ryu M. , Chen Y. , Qi J. , Liu J. , Fan Z. , Nam G. , Shi Y. , Cheng H. , Gao G.F.
      PLoS ONE6:E19245-E19245(2011) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.5 ANGSTROMS) OF 24-120;DISULFIDE BOND;FUNCTION
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