Gene name:
Lpar1 (Edg2;Gpcr26;Lpa1;Vzg1) ;
Protein name:
Lysophosphatidic acid receptor 1 (LPA receptor 1;LPA-1) ;
Alternative:
Rec1.3 ;Lysophosphatidic acid receptor Edg-2 ;VZG-1 ;
Organism:
Mouse (Mus musculus).
General Annotation
Sub Unit:
Interacts with RALA and ADRBK1.
Function:
Receptor for lysophosphatidic acid (LPA), a mediator of diverse cellular activities. Seems to be coupled to the G(i)/G(o), G(12)/G(13), and G(q) families of heteromeric G proteins. Stimulates phospholipase C (PLC) activity in a manner that is dependent on RALA activation.
Subcellular Location:
Cell surface
Cell membrane
Multi-pass membrane protein
Prior to LPA treatment found predominantly at the cell surface but in the presence of LPA co-localizes with RALA in the endocytic vesicles.
Protein Attributes:
50:
MAAASTSSPV | ISQPQFTAMN | EQQCFYNESI | AFFYNRSGKY | LATEWNTVSK |
100:
LVMGLGITVC | VFIMLANLLV | MVAIYVNRRF | HFPIYYLMAN | LAAADFFAGL |
150:
AYFYLMFNTG | PNTRRLTVST | WLLRQGLIDT | SLTASVANLL | AIAIERHITV |
200:
FRMQLHTRMS | NRRVVVVIVV | IWTMAIVMGA | IPSVGWNCIC | DIDHCSNMAP |
250:
LYSDSYLVFW | AIFNLVTFVV | MVVLYAHIFG | YVRQRTMRMS | RHSSGPRRNR |
300:
DTMMSLLKTV | VIVLGAFIVC | WTPGLVLLLL | DVCCPQCDVL | AYEKFFLLLA |
350:
EFNSAMNPII | YSYRDKEMSA | TFRQILCCQR | NENPNGPTEG | SDRSASSLNH |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Mouse
Rat
Bovine
ELISA Kit for Mouse LPA receptor 1
ELISA Kit for Mouse LPA receptor 1
ELISA Kit for Mouse LPA receptor 1
ELISA Kit for Mouse LPA receptor 1
CLIA Kit for Mouse LPA receptor 1
CLIA Kit for Mouse LPA receptor 1
CLIA Kit for Mouse LPA receptor 1
CLIA Kit for Mouse LPA receptor 1
Polyclonal Antibody for Mouse LPA receptor 1
Polyclonal Antibody for Mouse LPA receptor 1
Polyclonal Antibody for Mouse LPA receptor 1
Polyclonal Antibody for Mouse LPA receptor 1
Monoclonal Antibody for Mouse LPA receptor 1
Monoclonal Antibody for Mouse LPA receptor 1
Monoclonal Antibody for Mouse LPA receptor 1
Monoclonal Antibody for Mouse LPA receptor 1
Protein for Mouse LPA receptor 1
Protein for Mouse LPA receptor 1
Protein for Mouse LPA receptor 1
Protein for Mouse LPA receptor 1
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
strain :
BALB/c .
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2)
strain :
C57BL/6 .
tissue :
Brain .
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [GENOMIC DNA] (ISOFORMS 1 AND 2)
strain :
129/SvJ .
4.
"Lineage-specific biology revealed by a finished genome assembly of the mouse."
Church D.M.
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Goodstadt L.
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Hillier L.W.
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Zody M.C.
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Goldstein S.
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She X.
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Bult C.J.
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Cherry J.L.
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Kapustin Y.
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Meric P.
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Maglott D.
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Graves T.
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Zhou S.
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Place M.
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Herschleb J.
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Runnheim R.
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Forrest D.
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Ponting C.P.
more...
PLoS Biol.7:E1000112-E1000112(2009)
[
PubMed ]
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Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
strain :
C57BL/6J .
5.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
strain :
FVB/N-3 .
6.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : REVIEW