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Index > Protein center > Lpar1(Gene name) > Mouse
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  • Lpar1 (Gene name),
  • Lysophosphatidic acid receptor 1 (Protein name ),  LPAR1_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    Lpar1(Edg2;Gpcr26;Lpa1;Vzg1);
    Protein name:
    Lysophosphatidic acid receptor 1(LPA receptor 1;LPA-1);
    Alternative:
    Rec1.3;Lysophosphatidic acid receptor Edg-2;VZG-1;
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Interacts with RALA and ADRBK1.
    Function:
    Receptor for lysophosphatidic acid (LPA), a mediator of diverse cellular activities. Seems to be coupled to the G(i)/G(o), G(12)/G(13), and G(q) families of heteromeric G proteins. Stimulates phospholipase C (PLC) activity in a manner that is dependent on RALA activation.
    Subcellular Location:
    Cell surface Cell membrane Multi-pass membrane protein Prior to LPA treatment found predominantly at the cell surface but in the presence of LPA co-localizes with RALA in the endocytic vesicles.
    Protein Attributes:
    Sequence length:
    364
    Sequence:
    50:
    MAAASTSSPV | ISQPQFTAMN | EQQCFYNESI | AFFYNRSGKY | LATEWNTVSK | 
    100:
    LVMGLGITVC | VFIMLANLLV | MVAIYVNRRF | HFPIYYLMAN | LAAADFFAGL | 
    150:
    AYFYLMFNTG | PNTRRLTVST | WLLRQGLIDT | SLTASVANLL | AIAIERHITV | 
    200:
    FRMQLHTRMS | NRRVVVVIVV | IWTMAIVMGA | IPSVGWNCIC | DIDHCSNMAP | 
    250:
    LYSDSYLVFW | AIFNLVTFVV | MVVLYAHIFG | YVRQRTMRMS | RHSSGPRRNR | 
    300:
    DTMMSLLKTV | VIVLGAFIVC | WTPGLVLLLL | DVCCPQCDVL | AYEKFFLLLA | 
    350:
    EFNSAMNPII | YSYRDKEMSA | TFRQILCCQR | NENPNGPTEG | SDRSASSLNH | 
    364:
    TILAGVHSND | HSVV
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
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    Related Databases
    KEGG:
    String:
    SMR:
    Pfam:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse LPA receptor 1
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    E9739h
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    ELISA Kit for Mouse LPA receptor 1
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    E9739m
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    ELISA Kit for Mouse LPA receptor 1
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    E9739r
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    ELISA Kit for Mouse LPA receptor 1
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    E9739b
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    Packing:
    96T
    CLIA Kit for Mouse LPA receptor 1
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    U9739m
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    Packing:
    96T
    CLIA Kit for Mouse LPA receptor 1
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    U9739b
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Mouse LPA receptor 1
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    U9739r
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    96T
    CLIA Kit for Mouse LPA receptor 1
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    U9739h
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    Packing:
    96T
    Polyclonal Antibody for Mouse LPA receptor 1
    Polyclonal Antibody for Mouse LPA receptor 1
    Polyclonal Antibody for Mouse LPA receptor 1
    Cat.:
    P9739Rb-h
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse LPA receptor 1
    Cat.:
    P9739Rb-m
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    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Mouse LPA receptor 1
    Monoclonal Antibody for Mouse LPA receptor 1
    Monoclonal Antibody for Mouse LPA receptor 1
    Monoclonal Antibody for Mouse LPA receptor 1
    Protein for Mouse LPA receptor 1
    Protein for Mouse LPA receptor 1
    Protein for Mouse LPA receptor 1
    Protein for Mouse LPA receptor 1

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    References
    1. 1.
      "Ventricular zone gene-1 (vzg-1) encodes a lysophosphatidic acid receptor expressed in neurogenic regions of the developing cerebral cortex."
      Hecht J.H. , Weiner J.A. , Post S.R. , Chun J.
      J. Cell Biol.135:1071-1083(1996) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
      strain: BALB/c.
    2. 2.
      "Cloning, characterization, and chromosomal localization of rec1.3, a member of the G-protein-coupled receptor family highly expressed in brain."
      Macrae A.D. , Premont R.T. , Jaber M. , Petersen A.S. , Lefkowitz R.J.
      Brain Res. Mol. Brain Res.42:245-254(1996) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2)
      strain: C57BL/6.
      tissue: Brain.
    3. 3.
      "Complete cDNA sequence, genomic structure, and chromosomal localization of the LPA receptor gene, lpA1/vzg-1/Gpcr26."
      Contos J.J.A. , Chun J.
      Genomics51:364-378(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] (ISOFORMS 1 AND 2)
      strain: 129/SvJ.
    4. 4.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
      strain: C57BL/6J.
    5. 5.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      strain: FVB/N-3.
    6. 6.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: REVIEW
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